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ASCB's Pathways Podcast

ASCB's Pathways Podcast

By American Society for Cell Biology
Pathways Podcast is produced by the American Society for Cell Biology (ASCB) and features news and interviews for anyone interested in the life sciences.
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OpenCell Reveals the Dynamic Life of Proteins
Manuel Leonetti, group leader in Quantitative Cell Science at the Chan Zuckerberg Biohub in San Francisco, is taking the description of “proteins in the wild” a step further with his project called OpenCell.  Through advanced imaging techniques, machine learning, artificial intelligence, data science, and software engineering, OpenCell is able to measure the quantity and track the position of different proteins in human embryonic kidney cells through time and space. So far, Leonetti says, his group has mapped 1,310 different proteins, which might sound like a lot, but this represents just 7% of the human genome. Visit to learn more. 
May 24, 2022
How was MBoC's Preprints Highlights system developed?
Join Mike Lacy, the Curation Manager for Molecular Biology of the Cell journal's Preprint Highlights, and two of MBoC's Early Career Editors for a discussion on how the Preprint Highlights system of article evaluation was developed. Read more in this blog post from Mike: or visit the journal website curation page here:
May 02, 2022
Expansion Microscopy with Paul Tillberg
Paul Tillberg, now a Janelia Fellow at the Howard Hughes Medical Institute Janelia Research Campus, developed the protocol for expansion microscopy with colleagues Ed Boyden, currently a professor at MIT, and Fei Chen, currently a Core Institute Member at the Broad Institute. The method exploits the fact that biological tissue is mostly water, and it is this watery fraction, Tillberg explains, that is replaced by a “swellable hydrogel” that expands the sample to sizes that make it much easier to image with familiar fluorescent tags and standard light microscopy equipment.
March 24, 2022
Celebrating 20 years of CBE--Life Sciences Education
Join co-editors-in-chief Kimberly Tanner and Jeff Schinske for the launch of the 20th-anniversary celebration of ASCB CBE--Life Sciences Education journal, which published its first issue in March 2002. 
February 22, 2022
Cell Forces Tell an Important Story with Valerie Weaver
Valerie M. Weaver, Ph.D., is the Director of the Center for Bioengineering and Tissue Regeneration in the Department of Surgery. She is the editor for the special issues at Molecular Biology of the Cell on Forces on and Within Cells.
January 26, 2022
Meet ASCB's New CEO Rebecca Alvania
Rebecca Alvania joined the American Society for Cell Biology as the new CEO on January 3, 2022. 
January 26, 2022
How do Americans want to participate in science?
This month on the Pathways Podcast we interview Rose Hendricks, program director for the Society Civic Science initiative, which is based at ASCB. We will discuss her research project “Assessing How Americans Want to Participate in Science.”
November 03, 2021
Quantitative Biology: Embrace the Numbers
This month on the Pathways Podcast we talk to Alex Mogilner, one of the editors of the 8th Special Issue on Quantitative Biology, published by ASCB’s basic science research journal, Molecular Biology of the Cell.
October 01, 2021
Increasing diversity, equity, and inclusion at the annual meeting
For the September Pathways Podcast, we chat with ASCB Director of Meetings Alison Harris and Meeting Manager Danielle Raiford about CellBio Virtual 2021, including the new way speakers were chosen for the minisymposia and special interest subgroups.
September 07, 2021
How to help students use Metacognition for Learning
This month on the Pathways Podcast we speak with Julie Dangremond Stanton and Amanda Sebesta about their recent paper and teaching guide in CBE Life Sciences Education on using metacognition to help students learn. Their paper, Fostering Metacognition to Support Student Learning and Performance, can be found here.
August 02, 2021
What's new at Molecular Biology of the Cell with Matt Welch
The July Pathways Podcast features Matthew Welch, editor-in-chief for ASCB’s basic science research journal, Molecular Biology of the Cell.  We chat about new initiatives at MBoC and find out what sets our publication apart.
June 28, 2021
Creating Inclusive Spaces for LGBTQ+ Researchers with Lee Ligon and Katelyn Cooper
This month on the Pathways Podcast we interview Lee Ligon (Rensselaer Polytechnic Institute)  and Katelyn Cooper (Arizona State University) on how to create a more inclusive and welcoming environment in our laboratories and classroom for members of the LBGTQ+ community. For further reading, Fourteen Recommendations to Create a More Inclusive Environment for LGBTQ+ Individuals in Academic Biology.
June 01, 2021
How cells use ER associated autophagy for quality control with Doug Cyr
Doug Cyr of the University of North Carolina, Chapel Hill studies protein folding and misfolding and the molecules associated with it. His lab recently published a paper in ASCB's journal Molecular Biology of the Cell - DNAJB12 and Hsp70 Triage Arrested Intermediates of N1303K-CFTR for ER Associated-Autophagy. We discuss that paper and his lab's research overall.
May 03, 2021
What is 4D Cellular Physiology with Ron Vale and Jennifer Lippincott-Schwartz
The Howard Hughes Medical Institute is adding a new research focus -- 4D Cellular Physiology. On this episode of the Pathways Podcast from the American Society for Cell Biology we chat with Ron Vale, the Vice President and Executive Director of HHMI's Janelia Research Campus, and Jennifer Lippincott-Schwartz, a senior group leader also at Janelia, about this new direction and how it will impact the cell biology community. 
April 02, 2021