I am the founder of Scientific Nutrition and the author of The Optimized Guide to Intermittent Fasting and I want you to live a healthy life. In this workday show you will get a 5-10 minute update on something new or interesting in the world of health, fitness, or nutrition.
In this episode, inspired by Dr. William Lagakos' book "The poor, misunderstood calorie" I decide to take a deep dive into the science behind nutrient partitioning and simple things we can do to help maximize the effect.
Link to book:https://amzn.to/2HMQYAc
This episode is not normal, and you may want to skip. I give my thoughts on the first 50 episodes and some things I have learned. Unscripted and unedited, it is much less produced than many of my episodes.
This is a fun episode about a potential link between Trans fats and aggression. There was an interesting study done that suggested greater consumption of trans fats increased the aggression in people.
Lambda School Link: https://lambdaschool.com/scinutrient
This episode is heavy on the science. I got a question about whether or not arginine precursors may contribute to muscular recovery through interactions with macrophages and I had no idea so this whole episode you get to learn right along side me.
I love the sport of football. I played for 10 years and coached for 7. It is a sport that helped make me who I am today. However, there is increasing evidence, especially for linemen, linking it to higher rates of heart disease.
Creatine is a popular supplement among athletes, bodybuilders, powerlifters, and weightlifters. It has pretty significant evidence suggesting that it will improve muscular strength and sprint performance and limited evidence that it will improve your intelligence.
The reproducibility crisis is the biggest threat facing medicine right now in my opinion. A huge number of studies are failing to replicate and that is a terrifying thing, because decisions are being based on studies that may be inaccurate. There is one study that estimates as much as 50% of preclinical research may fail to replicate at a cost of $26 billion per year.
This episode is a bit longer than most, but the last several minutes are optional bonus content. I wanted to finally discuss my favorite polyphenol with you guys, resveratrol. It is commonly found in red wine, and for a long time many of the health benefits of red wine were attributed to it. However, many of those were based on mouse studies, and in this episode we see how many of those effects persist when we instead focus on human studies.
This is an episode about a study that I have seen circulating again that certain outlets claim suggests that tequila can help with weight loss. This is not supported by the study and moreover, represents a dangerous precedent in science reporting. The worse science reporting is the less people will trust science as a whole and more likely they will be convinced by pseudoscience.
The nocebo effect is the opposite of the placebo effect we covered in episode 36, it is when bad things happen when you take a sugar pill because you expect bad things to happen. This is actually surprisingly common and you can even see severe side effects like respiratory depression arising as a result of the nocebo effect.
Overall, in considering both the nocebo and the placebo effect the most important thing to keep in mind is that your psychology has power. It is important to remember that your mindset and your beliefs are going to have measurable impacts on your physiology and your health.
While most people do know what the placebo effect is they often fail to realize just how large the effect can be. The brain can respond in the same way to antidepressants and placebos. Placebos can actually induce respiratory depression in the same manner as opioids.
In this we look at the science of monosodium glutamate (MSG) a common food additive that many people claim to be sensitive to. It appears that it could be a useful tool for improving the nutrition of at risk populations.
Inspired by profiles in Tim Ferriss' book Tools of Titans I decided to try to determine the health effects of saunas on athletic performance. I feel for elite level athletes they are a potentially useful tool.
This episode is dedicated to confronting the stupidity of magnetized water, which is apparently a thing that people are marketing now. It's dumb. Do not buy it. They are trying to scam you. Or they got scammed and didn't realize it. Either way there are scam artists involved.
This is quick episode in which I rant about online communities that treat unsustainable weight loss as sustainable, or about communities that treat water weight loss as fat loss. Both of these are pet peeves of mine, because they are inaccurate, and make it less likely people will stick to the diets.
As we dive back into medicinal mushrooms we look at what is in my opinion one of the most fascinating, with kidney and liver protection, pain relief, anti-inflammatory effects, and it may even make you smarter.
This is my longest and probably my most in depth episode so far. In it we dive deep into trying to figure out whether there is a convincing link between calorie restriction and longevity, and what mechanisms may support this link.
Garcinia Cambogia, commonly marketed as a weight loss supplement does not work, and you should not purchase it. I get incredibly frustrated with charlatans and snake oil salesmen who try to market and sell things like this.
Lion's mane mushrooms are a potent nootropic, potential antibiotic and anti-cancer agent, powerful antioxidant, and an immunostimulant. One of the most powerful nootropics I have ever used and a compound I personally enjoy.
If you want to try an extract from these I recommend FourSigmatic and if you use the code "scinutrient" at checkout you will get 10% off. Full disclosure, I do receive a small commission if you do this.
Normally I am immensely skeptical of alternative medications, but there is some interesting science behind these reishi mushrooms. There is some compelling evidence that they may actually be a useful anti-cancer agent, and immuno-potentiating agent.
This episode is all about the incredible health benefits of walking, even for just small amounts of time. Seriously, I'm shocked at how huge these health effects are. Hat tip to Dr. William Lagakos Ph. D who started me down this research rabbit hole.
Stephen Hawking was a great and gentle man who gave us a better understanding of both the nature of the cosmos, and the beauty of humanity. He is one of the truly great men, and we all should mourn the passing of this incredible man, but always remember how Hawking would say "Life would be tragic, if it weren't so funny". I believe he would want us to fight life and light and joy despite this.
Warning: This episode contains significant vulgarity
Raw water is mostly just a few people on the west coast, but I still want to address this before it becomes a more serious issue. Do not drink raw water, you are risking your health for no benefit. Do not do it. Anyone trying to sell it to you is a charlatan, a quack, or a snake oil salesman. They do not deserve a penny of your money.
This episode is about the entire reason this podcast, my website, and everything else I do exists. Basically most nutritional science is awful. This episode explains my problems with one particularly problematic study and why nutritional science is such a struggle.
In this episode I discuss my experience with a longer 40 hour fast, and some advice on how to deal with it. Remember though that this kind of behavior can be dangerous, here is the number for an eating disorder hotline in case you are worried you may have or are developing an eating disorder: 1-800-931-2237