Skip to main content
Hack your gut

Hack your gut

By Dave Mayo

Join me as I discuss the many ways that our lifestyle behaviors affect gut health. I'll cover topics including circadian rhythms, sleep, exercise, diet, and much more.
Available on
Apple Podcasts Logo
Google Podcasts Logo
Overcast Logo
Pocket Casts Logo
RadioPublic Logo
Spotify Logo
Currently playing episode

It’s about time functional medicine treats the root cause of chronic disease!

Hack your gutMar 04, 2019

00:00
55:06
How I developed my optimized lifestyle

How I developed my optimized lifestyle

I’m this episode of the podcast, I discuss how I developed my personalized, optimized lifestyle. It took a lot of trial and error, and being precise with how I tweak things. The result: happy, healthy and thriving!
Sep 16, 202037:52
The Truth about Chronotype

The Truth about Chronotype

In this podcast, we discuss what your chronotype is, factors that affect your chronotype, and the process we use for shifting chronotype.
Sep 03, 202028:21
Meal scheduling Q&A

Meal scheduling Q&A

In this episode we cover some reader/listener questions on meal timing.
Aug 25, 202042:35
Gut health, aging, and the epigenetic clock

Gut health, aging, and the epigenetic clock

In this episode of the podcast, we discuss the importance of gut health to healthy aging. Evidence indicates that “leaky gut” may speed up the aging process by altering the epigenome. Speeding up the epigenetic clock can have damaging effects on our health. Fortunately, there are a few things we can do on a day to day basis to improve gut health and potentially delay age-related functional decline.
Aug 12, 202043:35
Ep. 14: How VT is crushing COVID-19, CFS after COVID-19, and my self-care routine

Ep. 14: How VT is crushing COVID-19, CFS after COVID-19, and my self-care routine

Learn about how science is driving VT’s success in controlling COVID-19, the wide range of post-viral symptoms people experience, and the self-care I’ll be doing for the next month to maximize my resilience
Jul 24, 202038:48
Episode 13: Epigenetic aging, senescent cells, the skin-gut axis, and more

Episode 13: Epigenetic aging, senescent cells, the skin-gut axis, and more

Learn what epigenetic age is and how it affects the gut, how senescent cells accelerate age, how skin health affects the gut, and more...
Jul 21, 202043:29
Episode 12: my diet & exercise, red light improves vision, & inflammaging

Episode 12: my diet & exercise, red light improves vision, & inflammaging

In this episode I discuss my current nutrition and exercise plans, how red light improves vision, how inflammation speeds aging, and how the polyphenol apigenin can reduce age-related NAD+ decline.
Jul 07, 202034:09
Ep. 11-Current protocol, COVID-19, meal spacing/timing for gut health, delayed blue blocking

Ep. 11-Current protocol, COVID-19, meal spacing/timing for gut health, delayed blue blocking

In this episode I cover my current supplement and lifestyle protocol for optimal health, musing on COVID-19, meal spacing & timing for gut health, and why blocking blue light later at night may cause you to wake up earlier.
Jul 01, 202021:15
It’s about time functional medicine treats the root cause of chronic disease!

It’s about time functional medicine treats the root cause of chronic disease!

Synopsis We all hear about how important treating "root causes" is for solving chronic health problems. In fact, the reason conventional medicine is so bad at treating chronic disease is because it manages symptoms rather than treating "root causes". But how we define "root causes" is very important, because the narrative in the functional medicine … Continue reading It’s about time functional medicine treats the root cause of chronic disease!
The post It’s about time functional medicine treats the root cause of chronic disease! appeared first on Hack your gut.
Mar 04, 201955:06
Is your lifestyle causing your gastrointestinal disease?

Is your lifestyle causing your gastrointestinal disease?

If you have a functional gastrointestinal disease like IBS or SIBO, the quote below may not resonate with you if. Particularly if you don't work the night shift or skip over times zones while traveling. Obviously you don't have circadian disruption, you go to bed at night just like everyone else, right? "...all parts of … Continue reading Is your lifestyle causing your gastrointestinal disease?
The post Is your lifestyle causing your gastrointestinal disease? appeared first on Hack your gut.
Jan 28, 201923:09
5 simple science-based tips to improve digestion

5 simple science-based tips to improve digestion

Many people, particularly those with gut problems, want to improve digestion. This almost always involves a trove of supplements that don't always pan out. Though you can get a lot more benefit from changing behavior, many simply don't know this. Modern medicine has a way of approaching human health that involves isolating affected systems and … Continue reading 5 simple science-based tips to improve digestion
The post 5 simple science-based tips to improve digestion appeared first on Hack your gut.
Jan 14, 201924:20
Podcast 9: 4 powerful ways that leaky gut ages you faster

Podcast 9: 4 powerful ways that leaky gut ages you faster

It's been a while since I've covered the importance of gut health for healthy aging, but today's the day to jump right back in to the swing of things. A study published late last year found that disease-free centenarians seem to have much healthier guts than younger people when it comes to 2 key … Continue reading Podcast 9: 4 powerful ways that leaky gut ages you faster
The post Podcast 9: 4 powerful ways that leaky gut ages you faster appeared first on Hack your gut.
Jan 07, 201934:11
Podcast 8: Solving leaky gut

Podcast 8: Solving leaky gut

Note: I go much deeper in the weeds in the podcast version of this blog. I also include some pretty nifty hacks that increases blood flow to the gut. If you listen and like the podcast via itunes or any of the other podcast apps, leave me a review letting me know if you … Continue reading Podcast 8: Solving leaky gut
The post Podcast 8: Solving leaky gut appeared first on Hack your gut.
Dec 17, 201836:35
Podcast 7: What is the Stop Leaky Gut Challenge?

Podcast 7: What is the Stop Leaky Gut Challenge?

youtu.be/LmMuLbuvbjk Hey folks, did a little video and podcast rundown of what we'll be doing for the Stop Leaky Gut Challenge starting January 1st. We'll be working on shaping behavior for 12 weeks in order to bring our guts in to tip top shape. In this presentation, I give the underlying principles behind the … Continue reading Podcast 7: What is the Stop Leaky Gut Challenge?
The post Podcast 7: What is the Stop Leaky Gut Challenge? appeared first on Hack your gut.
Dec 10, 201825:33
Why you must optimize metabolic health to heal your gut

Why you must optimize metabolic health to heal your gut

To heal your gut, optimal metabolic health is a must. A recent study found that 12.2% of the US population has optimal metabolic health. When you consider that this includes all adults over the age of 18, you may be a bit shocked. Me, not so much. From my perspective, this number feels about right. … Continue reading Why you must optimize metabolic health to heal your gut
The post Why you must optimize metabolic health to heal your gut appeared first on Hack your gut.
Dec 03, 201834:16
Optimizing cardiometabolic health to reverse chronic disease

Optimizing cardiometabolic health to reverse chronic disease

Poor cardiometabolic health is both a consequence and driver of chronic disease. In this episode of the podcast, I cover what cardiometabolic health is and why you should address it to prevent or reverse chronic disease. In the next episode of the podcast I take a deeper dive in to how metabolic dysfunction drives chronic … Continue reading Optimizing cardiometabolic health to reverse chronic disease
The post Optimizing cardiometabolic health to reverse chronic disease appeared first on Hack your gut.
Nov 27, 201836:01
Podcast #4: What circadian rhythms do

Podcast #4: What circadian rhythms do

What are circadian rhythms? Biological functions that vary over a 24 hour period Sleep, activity, digestion, immunity, & motivation WRT to digestion, enzyme synthesis/secretion, gastric acidity, intestinal permeability, and motility are all circadian At the cellular level, circadian rhythms help separate use from repair Circadian rhythms help you solve the puzzle that is the … Continue reading Podcast #4: What circadian rhythms do The post Podcast #4: What circadian rhythms do appeared first on Hack your gut.
Nov 19, 201820:03
Podcast #3-Cellular energy metabolism and the mitochondria

Podcast #3-Cellular energy metabolism and the mitochondria

In this podcast I cover basic energy metabolism within the cell, with particular emphasis on how the mitochondria play a role. I also discuss the NAD+/NADH and things that lead to the age-related decline in the NAD+ pool and how circadian rhythms fit in to the picture. Below are the pictures and outline for … Continue reading Podcast #3-Cellular energy metabolism and the mitochondria
The post Podcast #3-Cellular energy metabolism and the mitochondria appeared first on Hack your gut.
Nov 14, 201824:57