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Talking Precision Medicine

Talking Precision Medicine

By Genialis

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.
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Building the Team to Decode Biology with Tina Larson | Talking Precision Medicine #16

Talking Precision MedicineNov 05, 2019

00:00
37:39
The Science and Art of De-risking Cancer Drug Development | Talking Precision Medicine #35
Apr 12, 202431:27
Professional grade software — a key ingredient in cutting edge biomedical discovery | Talking Precision Medicine #34
Dec 14, 202331:38
New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33
Oct 27, 202342:45
To achieve personalized medicine, start by getting the dose right | Talking Precision Medicine #32
Aug 02, 202339:14
AI and Ethics in Healthtech: Who is Innovating Most? | Talking Precision Medicine #31
Jun 29, 202334:41
People first: building a company that inspires impactful work | Talking Precision Medicine #30
May 31, 202351:07
Communication, the key to building community | Talking Precision Medicine #29
Jan 26, 202344:54
A new way to finance drug development, for rare disease and beyond | Talking Precision Medicine #28
Nov 30, 202245:37
What’s in a Name?: Endpoint Health’s Patient-Centric Northstar | Talking Precision Medicine #27
Jun 27, 202243:16
Taking charge of your health future with wearables and AI | Talking Precision Medicine #26
Feb 28, 202233:34
Real-Time Multiplexed Biomarkers: The Next Generation of Continuous Monitoring | Talking Precision Medicine #25
Sep 05, 202131:48
Fostering Patient Journeys Around the World | Talking Precision Medicine #24
Jul 28, 202140:43
From Cancer to Covid, Drug Intelligent Science at Breakneck Pace | Talking Precision Medicine #23
Feb 26, 202147:19
Ethics and Policies of Precision Medicine on the Global Stage | Talking Precision Medicine #22
Nov 19, 202049:32
Rebooting generics to fight cancer | Talking Precision Medicine #21
Aug 31, 202051:12
Stopping sepsis in its tracks… oh, and COVID19 too! | Talking Precision Medicine #20
Jun 11, 202046:55
Meet the viruses that are saving lives with Rob McBride | Talking Precision Medicine #19
Mar 17, 202036:28
DNA solves the oldest cold case with David Mittelman | Talking Precision Medicine #18
Mar 04, 202033:20
Launching the Hubble Telescope to Cure Cancer with Charlie Silver and Nigel Beard | Talking Precision Medicine #17
Jan 09, 202038:29
Building the Team to Decode Biology with Tina Larson | Talking Precision Medicine #16

Building the Team to Decode Biology with Tina Larson | Talking Precision Medicine #16

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. 

This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today our guest is Tina Larson. Tina is COO of Recursion Pharmaceuticals, where she is tasked with building the team, the operations and the culture to tackle Recursion’s audacious goals. Tina has over 20 years of experience in the biopharmaceutical industry, and was recently awarded the 2019 Distinguished Alumni Award from her alma mater Colorado State University.

In this episode, we talk about the language of multidisciplinary teams, recruiting top talent while fostering inclusivity, and the promise of melding tech and biology to advance treatments at unprecedented scale.


Nov 05, 201937:39
The Genomics of Justice with David Mittelman | Talking Precision Medicine #15

The Genomics of Justice with David Mittelman | Talking Precision Medicine #15

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. 

This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today our guest is David Mittelman. David is CEO of Othram, the first genomics-based forensics company. David is also a serial genomics entrepreneur, and, like Genialis, based in Houston.

In this episode, David explains his vision for disrupting the state of the art in forensics identification using genomics, deep sequencing and machine learning. A bit of a departure from the usual themes around medical applications of data and data science.


Oct 10, 201939:27
Garbage in, garbage out? Solve data preprocessing with Gabe Musso | Talking Precision Medicine #14

Garbage in, garbage out? Solve data preprocessing with Gabe Musso | Talking Precision Medicine #14

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. 

This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today our guest is Gabe Musso. Gabe is Chief Scientific Officer of BioSymetrics, a Toronto-based biomedical AI company empowering healthcare and R&D innovation. 

In this episode, Gabe tells us how BioSymetrics is working to clean up data clean up, by applying a rigorous product framework to data preprocessing. 


Sep 17, 201936:16
Twenty-two suicides, every damn day with Yusuf Henriques | Talking Precision Medicine #13

Twenty-two suicides, every damn day with Yusuf Henriques | Talking Precision Medicine #13

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.

Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics.


Today our guest is Yusuf Henriques. Yusuf is co-founder and CEO of TruGenomix, a precision medicine company focused on the early detection and prevention of PTSD in military veterans and first responders.

In this episode, Yusuf reminds us that every day counts. Because every day there are 20 to 22 veteran suicides. This is what keeps Yusuf up at night, and keeps him pushing on all fronts to innovate a solution.

Jul 23, 201934:39
Organizing the world’s variant data for genomic medicine with Mark Kiel | Talking Precision Medicine #12

Organizing the world’s variant data for genomic medicine with Mark Kiel | Talking Precision Medicine #12

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. 

Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today we speak with Mark Kiel. Mark is the founder and Chief Scientific Officer at Genomenon where he shepherds the product vision and implementation of the Mastermind suite of software tools.

He completed an MD / PhD  fellowship in Molecular Genetic Pathology at the University of Michigan. 

In this episode, Mark describes the genesis of his vision to organize the world’s molecular data and his journey to realize the promise of genomic medicine.


Jun 14, 201939:48
The evolving business landscape of health-tech with Luba Greenwood | Talking Precision Medicine #11

The evolving business landscape of health-tech with Luba Greenwood | Talking Precision Medicine #11

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. 

Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today we speak with Luba Greenwood, who works in Strategic Business Development and Corporate Ventures at Verily, an Alphabet company. 

Luba brings to Google her experience in pharmaceutical, biotechnology, and digital health industries. Not to mention her expertise in building and investing in innovative technology companies. 

She is on the Board of MassBio and Brooklyn ImmunoTherapeutics, and serves as an Advisor to the Dana Farber Cancer Institute.

In this episode, we dive into Luba’s work across the intersections of healthcare and technology.


May 28, 201928:26
The hottest time in gene therapy, ever! with Nicole Paulk | Talking Precision Medicine #10

The hottest time in gene therapy, ever! with Nicole Paulk | Talking Precision Medicine #10

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. 

Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today we speak with Dr. Nicole Paulk. Nicole is an assistant professor at the University of California San Francisco, and the Advisory Lead for Genome Engineering at Chan Zuckerberg Biohub. 

Nicole’s lab builds technologies to advance the entire field of viral gene therapy. They are a force behind the rising tide lifting the gene therapy industry. She is also committed to training the next generation of scientist innovators. 

Apr 30, 201931:08
Building trust in rare disease with Julie Walters | Talking Precision Medicine #09

Building trust in rare disease with Julie Walters | Talking Precision Medicine #09

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. 

Genialis is focused on data integration and predictive modeling of disease biology to help accelerate the discovery and de-risk the development of novel therapeutics. 


Today we speak with Julie Walters. Julie is the founder of Raremark, an information hub about rare disease for patients and their families. She has a degree in molecular genetics and a background in popular journalism… and is an entrepreneur by nature. In fact, she was a Female Entrepreneur of the Year at the UK’s 2017 Enterprise Awards. 

Julie believes in harnessing the power of families affected by a rare disease, and our discussion covers many of the ways Raremark aims to do just that. 


Apr 02, 201928:57
Standing up the Alliance for AI in Healthcare with Annastasiah Mhaka | Talking Precision Medicine #08

Standing up the Alliance for AI in Healthcare with Annastasiah Mhaka | Talking Precision Medicine #08

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.

Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics.

Today’s podcast is a special episode of Talking Precision Medicine, dedicated to the Alliance for Artificial Intelligence in Healthcare. The A-A-I-H saw its official hard launch at JP Morgan this past January, with a standing-room-only panel discussion at the Biotech Showcase. Our guest today is Dr. Annastasiah Mhaka, a Senior Advisor at Adjuvant Partners and the muscle behind standing up the AAIH.

The Alliance is a global organization that aims to improve patient quality of life by creating more effective, sustainable, and accessible healthcare. Through its work on education, regulatory issues, technology standards, and more, the AAIH will foster the responsible development of emerging industry segments poised to have a tremendous impact across the healthcare spectrum.

At the end of our conversation with Annastasiah, we include some bonus material recorded at The Future of AI-Powered Healthcare panel discussion at JPM.

Full disclosure— Genialis is a founding member of the AAIH, and its CEO, Rafael Rosengarten, is a board director.

Mar 05, 201936:41
Modeling systems from organoids to EHRs with Olivier Elemento | Talking Precision Medicine #07

Modeling systems from organoids to EHRs with Olivier Elemento | Talking Precision Medicine #07

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.


Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics.


Today we speak with Olivier Elemento. Olivier is the Director of the Englander Institute for Precision Medicine, as well as Associate Director of the Institute for Computational Biomedicine, both at Weill Cornell Medicine. He is also co-founder of OneThree Biotech. Olivier is a practitioner par excellence, in applying advanced analytics to large genomic and patient datasets. 


Our conversation covered a lot of ground, including curated knowledge bases, patient consent, breakthroughs in preclinical models, and even AR/VR.

Feb 19, 201938:34
Where were you when the FDA approved CAR-T? with Patrick Hanley | Talking Precision Medicine #06

Where were you when the FDA approved CAR-T? with Patrick Hanley | Talking Precision Medicine #06

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.


Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics.


Today we speak with Patrick Hanley. Patrick works at the Children’s National Hospital in Washington DC, where he serves as the director of Good Manufacturing Practices for Immunotherapy. He is also a co-founder and vice president at Mana Therapeutics — a cell therapy company harnessing our immune cells to combat cancer. He is an expert in designing and manufacturing cell therapies... and was once a fierce competitor on the Houston indoor soccer circuit. 


We talk about the leaps and bounds of progress in cell therapy, and the challenges—including discovery, manufacturing, and distribution—that lay ahead.

Feb 05, 201931:09
Long on evidence, strong on science with Matthew Michelson | Talking Precision Medicine #05

Long on evidence, strong on science with Matthew Michelson | Talking Precision Medicine #05

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.


Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics.


Today we speak with Matthew Michelson. Matthew is CEO of Evid Science — a technology company using AI to make access to medical evidence as simple and seamless as possible. He is an expert in machine learning and natural language processing and an enthusiastic company builder. 


We talk about how Evid supports evidence-based medicine, the value of well curated information, and the importance of doing the work to validate your science.

Jan 22, 201939:56
The organic intelligence of families in need with Ethan Perlstein | Talking Precision Medicine #04

The organic intelligence of families in need with Ethan Perlstein | Talking Precision Medicine #04

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.


Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics.


Today we speak with Ethan Perlstein. Ethan is CEO at Perlara — a scientific discovery public benefit corporation that works with families, advocacy groups and BioPharma companies to develop cures for rare diseases. Perlara challenges the conventional approach to drug discovery through its scientific platform for evolutionary pharmacology.


We talk about Perlara’s approach to rare disease drug discovery; The power of working with families and foundations; as well as “Organic intelligence,” and what we can learn from biology. 

Jan 08, 201930:23
The data-driven storyteller with Elia Stupka | Talking Precision Medicine #03

The data-driven storyteller with Elia Stupka | Talking Precision Medicine #03

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling of disease biology… to help accelerate the discovery and de-risk the development of novel therapeutics. Today we speak with Elia Stupka. Elia is the Chief Analytics Officer and Senior Vice President of the Life Sciences Business at Health Catalyst — a next-generation data, analytics, and decision-support company. He has deep experience leading interdisciplinary teams in academia and industry encompassing fields such as genomics, computational biology, data science, AI and NLP and is a true visionary leader with a passion for innovation in health and life sciences. At Health Catalyst Elia is leveraging company's data to advance the life sciences—from drug discovery to understanding the patient impact of specific medications. The conversation covers a lot of ground, including Elia’s take on: using data at the point of care; key challenges in making therapeutic innovation accessible to the population at large; and the importance of storytelling in work and in life. 

Dec 19, 201832:47
AI could be made illegal tomorrow with Jonny Wray | Talking Precision Medicine #02

AI could be made illegal tomorrow with Jonny Wray | Talking Precision Medicine #02

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host. Genialis is focused on data integration and predictive modeling in precision medicine. We help accelerate the discovery and de-risk the development of novel therapeutics. From heterogeneous data and diverse information stores, we predict with confidence drug targets and biomarkers of tolerance, efficacy and outcome. Today we speak with Jonny Wray. Jonny is the Head of Discovery Informatics at e-therapeutics—a network-driven drug discovery company. He has extensive experience in applying mathematical and computational techniques to the modeling and analysis of biological systems, and is responsible for the conceptual formulation of the network-driven drug discovery approach pioneered at e-Therapeutics. We talk about everything from appreciating the complexity of biology to mechanistic modeling to discovering an entirely new chemical compound.

Dec 12, 201830:37
AI, it’s all about the drugs with Asim Siddiqui | Talking Precision Medicine #01

AI, it’s all about the drugs with Asim Siddiqui | Talking Precision Medicine #01

In Talking Precision Medicine podcast we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.

Genialis is focused on data integration and predictive modeling in precision medicine. We help accelerate the discovery and de-risk the development of novel therapeutics. From heterogeneous data and diverse information stores, we predict with confidence drug targets and biomarkers of tolerance, efficacy and outcome.

In this episode we speak with Asim Siddiqui. Asim is the CTO at NuMedii—a data driven drug discovery company. He has deep experience in computational biology, software engineering, next-generation sequencing, and cancer informatics, and is responsible for architecting and applying NuMedii’s AIDD (Artificial Intelligence for Drug Discovery) technology.

We talk about leveraging public data for discovery, communicating between data scientists, bench scientists and other stakeholders, and the potential and challenges of using AI to advance drug development.
Nov 28, 201832:46