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Facing the Cancer Revolution

Facing the Cancer Revolution

By The Cancer Revolution

The Cancer Revolution podcast series looks to explore all areas of integrative, traditional and alternative means of beating cancer and creating sustained good health, for the young folks and old.
Our topics will include areas such as immune system, metabolic theory, epigenetic, microbial connections, diet, mitigating side effects of cancer treatments, detoxification methods, anticancer nutrition, the latest news and stories in institutional cancer research

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Discovery of Biomarker-driven therapies for previously untreatable cases of lung cancer

Facing the Cancer RevolutionNov 06, 2020

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01:55:36
New Hope For a new modified CAR T Therapy For Multiple Myeloma and other fatal hematologic malignancies

New Hope For a new modified CAR T Therapy For Multiple Myeloma and other fatal hematologic malignancies

In this episode of Facing the Cancer Revolution Podcast we discuss Multiple myeloma cancer and new CAR-T Treatments for bone marrow cancers.

Multiple myeloma is a type of blood cancer that affects plasma cells, which are a type of white blood cells that produce antibodies to help fight infections. Treatment options for multiple myeloma have improved significantly in recent years with the introduction of new drugs and therapies.

  • Immunomodulatory Drugs (IMiDs): boost the immune system and target cancer cells. .
  • Proteasome inhibitors: Proteasomes are enzymes that break down proteins in cells, including those that cause cancer cells to grow.
  • Monoclonal antibodies: These are drugs that target specific proteins on the surface of cancer cells. .
  • CAR T-cell therapy: This is a type of immunotherapy where T cells (a type of immune cell) are modified in a laboratory to produce chimeric antigen receptors (CARs) that recognize and attack cancer cells.
  • High-dose chemotherapy and stem cell transplant: This treatment involves high-dose chemotherapy to kill cancer cells followed by a stem cell transplant to replace the damaged cells.
  • Targeted therapy: This is a type of treatment that targets specific molecules or genes that are involved in the growth and survival of cancer cells. .

Resources Discussed in Podcast

https://www.dana-farber.org/cellular-therapies-program/car-t-cell-therapy/car-t-cell-therapy-for-multiple-myeloma/

https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/symptoms-causes/syc-20353378

https://stemcellthailand.org/oncology/multiple-myeloma-treatment/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439649/

https://www.mdanderson.org/cancerwise/car-t-cell-therapy-puts-smoldering-and-multiple-myeloma-survivor-in-remission.h00-159543690.html

Links to Previous Shows

  1. Cancer immunotherapy: from T cell basics 
  2. Next generation of cancer treatments
  3. Advanced liver cancer
  4. Management of Liver Cancer
  5. Biomarker-driven therapies for lung cancer
  6. Understanding Carcinogenesis
  7. Prostate Cancer
  8. Pancreatic Cancer
Feb 24, 202356:30
Research links pancreatic cancer survival rates with arrangement of immune cells in tumors

Research links pancreatic cancer survival rates with arrangement of immune cells in tumors

In this episode of Facing the Cancer Revolution Podcast we discuss pancreatic cancer to stop prostate cancers and exocrine cancers. We discuss breakthough research, improvements in available treatments.

Pancreatic cancer is frequently diagnosed at an advanced stage, which makes it difficult to treat. It remains relatively rare (about 3% of cancers), but one of the most feared. When possible, pancreatic cancer is treated with surgical measures combined with stem cells and chemotherapy treatment. Non-operable cancers are treated with chemotherapy, possibly supplemented by immunotherapy.

Because they remain symptomless for a long time, pancreatic cancers are diagnosed at a late stage in 80 to 90% of cases. Their treatment is therefore often difficult. They remain rare, representing approximately 3% of cancers. In France, between 8 and 10,000 new cases of pancreatic cancer are diagnosed each year, causing about as many deaths. Pancreatic cancer is slightly more common in men. The average age at diagnosis is 75 years in men and 80 years in women.

In 90% of cases, pancreatic cancer develops from cells that line the ducts leading pancreatic juice to the intestine (see box): this is ductal adenocarcinoma of the pancreas. Most often (70 to 80% of cases), this cancer is born in the part of the pancreas which is close to the small intestine (the "head" of the pancreas).

Resources Discussed in Podcast

Links to Previous Shows

  1. Cancer immunotherapy: from T cell basics 
  2. Next generation of cancer treatments
  3. Advanced liver cancer
  4. Management of Liver Cancer
  5. Biomarker-driven therapies for lung cancer
  6. Understanding Carcinogenesis
  7. Prostate Cancer
Oct 26, 202237:38
New Immunotherapy Clinical Trials Gives Renewed Hope to Patients with Previously Incurable Prostate Cancer

New Immunotherapy Clinical Trials Gives Renewed Hope to Patients with Previously Incurable Prostate Cancer

In this episode of Facing the Cancer Revolution Podcast we discuss prostate cancer to stop prostate cancers reputation of being a killer. We discuss groundbreaking research, drive improvements in treatments, and fight injustice in pallative care.

Traditional treatments for prostate cancer has many side effects. The most common ones are diarrhea, leaking stool, blood in urine, and burning when you pee. It can also cause problems with erection. But, most of these symptoms will go away after the treatment is finished. This treatment can help treat prostate cancer. Read on to learn more about prostate cancer side effects. It can help you decide if the treatment is right for you. It can also save your life.

A doctor will grade prostate cancer according to the Gleason score. The Gleason score is based on the appearance of cells, and a lower score indicates a less aggressive cancer. The Gleason score is the first step in deciding if you have prostate cancer. The Gleason grade is given to each patient based on the grade of cancer cells present in the cancer. The lowest grade is grade one, while the highest grade is grade five. A Gleason score of six represents a low-grade cancer, while a Gleason score of seven or eight indicates a moderate or high-grade cancer.

The Gleason score can be very helpful in determining whether or not you have prostate cancer. If you have a high-grade tumor on a needle biopsy, it will be included in your Gleason score. 

Resources Discussed in Podcast

Links to Previous Shows

  1. Cancer immunotherapy: from T cell basics 
  2. Next generation of cancer treatments
  3. Advanced liver cancer
  4. Management of Liver Cancer
  5. Biomarker-driven therapies for lung cancer
  6. Understanding Carcinogenesis
Oct 18, 202247:43
A Podcast about cancer immunotherapy: from T cell basic science to clinical practice

A Podcast about cancer immunotherapy: from T cell basic science to clinical practice

Immunotherapy for cancer is the artificial activation of your body's immune system to battle cancer, enhancing the body's natural capacity to fight off the disease. It's a medical application of an emerging field of oncology and the basic research of cancer immunology. Immunotherapy may involve the administration of drugs directly to the site of cell activity or it may work by encouraging your own body's immune cells to attack the cancerous cells. This may be undertaken in conjunction with traditional therapy

Of the two methods, chemotherapy seems to be the more popular choice for patients suffering from solid cancers, particularly those with breast, cervical, or lung cancers. Although chemotherapy is successful in removing all traces of cancer cells, it also leaves many patients with some long-term side effects, such as hair loss, nausea, vomiting, and nausea. These can lead to the temptation to try alternative therapies, such as immunotherapy for cancer. But although this therapy is relatively new, and relatively new technology has brought it to us, it can be very risky and even deadly, for certain patients. So why would anyone want to consider this route?

The major benefit of immunotherapy for cancer involves boosting the immune checkpoints, which are protein complexes that serve as gateways between the body's defense systems and cancer cells. When these checkpoints are compromised, the immune defense systems can no longer protect the body from invading viruses and bacteria. As a result, the cancer cells can easily take over. By boosting their defenses, antibodies can then attack these invading agents, and the invasion of these alien cells can be stopped.

Unlike chemotherapy, immunotherapy has very few long-term side effects, although there may be some minor ones associated with the administration of immune checkpoint inhibitors. On the other hand, conventional therapies, such as chemotherapy and radiation, come with a huge price tag, and many people simply cannot afford them. Also, chemotherapy is not a cure, it is only a treatment. Once you stop the treatment, the cancer will continue to grow. And in the case of advanced cancers, it can also kill healthy cells, which leads to further infections, and ultimately, a fatal disease.

Links from the show

https://www.cancer.gov/about-cancer/treatment/types/immunotherapy

https://lungcancer.tistory.com/ 

https://pbase.com/dradams/stem_cells_for_cancer/ 

http://mikan.la.coocan.jp/cgi/m-k-n/calendar/schedule.cgi?year=2021&mon=04&day=27

https://www.webmd.com/cancer/immunotherapy-risks-benefits

Oct 26, 202122:20
New research helping to drive the next generation of cancer treatments
Oct 12, 202146:58
Surveillance & Treatment options for Advanced liver cancer
Jul 15, 202124:44
Diagnosis and Management of Liver Cancer

Diagnosis and Management of Liver Cancer

In this episode we discuss liver cancer, particularly (HCC) hepatocellular carcinoma and cholangiocarcinoma. The podcast also touches on focal nodular hyperplasia of the liver and haemangiomas of the liver.

This episode covers the pathophysiology, presentation of HCC, diagnosis, complications and management of liver cancer.

Liver cancer is a disease of the liver and can be a difficult one to detect in the early stages. It falls under the category of cancer that originates from the epithelial cells that form the liver. Cancer cells grow and divide rapidly while the rest of the cells are unable to divide and grow. The result is that the cancerous cells grow rapidly and form tumors. It is a common misconception that liver cancer is only the result of a virus. In fact, the most common cause of liver cancer is cirrhosis, which is the result of chronic liver disease.

There are three stages of liver cancer, each of which causes a different type of cancer. Stage I is not a cancer at all, but rather a normal tissue growth called a hemangioma. Stage II and III are both tumors. The differences between these cancers are that the first is a low-grade tumor that can usually be surgically removed, while the second has an aggressive, life-threatening nature. The third stage, however, is what causes liver cancer to be referred to as stage IV, or metastatic. The symptoms of liver cancer are the same as the symptoms of other types of cancer. But in this case, it is liver cell death rather than a clinical condition that affects the liver.  A person experiencing any of the symptoms of liver cancer should consult their doctor right away.

Links to show notes:

  1. Cancer Support Community
  2. Liver Cancer Symptoms and treatment options
  3. Stem Cell Treatment for Liver Cancer
  4. Liver Cancer Support Community
Mar 17, 202101:00:18
Discovery of Biomarker-driven therapies for previously untreatable cases of lung cancer
Nov 06, 202001:55:36
The Stem Cell Theory of Cancer - Understanding Carcinogenesis
Oct 21, 202001:12:03