In The Flow: Conversations with Pioneers in Pediatric Heart Failure
By Neha Bansal
This podcast aims to capture the stories of trailblazers and pioneers in the field pediatric heart failure and transplantation. These leaders represent a unique tribe and I will attempt to document their contributions in maturing this field from nothingness to the incredible successes today. We should never forget where we came from and the backstory is in the struggles and even failures. A historical analysis of ideas and events uniformly brings modesty, widening of horizons and a sense of wonderment. That is the aim of this podcast.
Dr. Lori West is Professor in the Depts. of Pediatrics, Surgery, Medical Microbiology/Immunology and Laboratory Medicine/Pathology at the University of Alberta and a pioneer in the field of ABO incompatible heart transplantation in infants. In 2001 West reported the first ever series of 10 infants who received ABO-incompatible heart transplantation (ABOi HTx) in the Hospital for Sick Children in Toronto, Canada.
Dr. Simon Urschel is an Associate Professor in the Department of Pediatrics at University of Alberta and the Clinical Director of the Pediatric Cardiac Transplant Program at Stollery Children’s Hospital. He has led the recent clinical efforts to focus on exploring the limits and boundaries and long term outcomes in these patients from large patient registries.
Transplantation of hearts from ABO-incompatible donors is contraindicated because of the risk of hyperacute rejection mediated by preformed antibodies in the recipient to blood-group antigens of the donor. Let’s listen to our two experts as to why this contraindication may not apply to newborn infants and how this field of ABOi heart transplantation has evolved.
Please check the ISHLT History Project : https://ishlt.org/about-ishlt/history-archives
Join me as I discuss with Dr. Lipshultz the formation of the Pediatric Cardiomyopathy Registry (PCMR). We will walk through how he came up with the idea, the challenges he faced along the way and also how the PCMR has revolutionized the care for children with cardiomyopathies.
Please visit the websites for:
Children's Cardiomyopathy Foundation : https://www.childrenscardiomyopathy.org/pages/childrens-cardiomyopathy-foundation/
The Kyle John Rymiszewski FOundation : http://www.kylejohnrymiszewskifoundation.org/
Hope you enjoy the episode and join me for the next one. Until then- Namaste!