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Petri Dish

Petri Dish

By Petri Dish
Profane, insane, and 100% primo science, Petri Dish is a no-BS podcast that explores the wildest subjects in modern science with clarity and evil joy.

Hosted by Sean Allen, a Nanoparticle/Immunology Researcher, and Nathan Allen, his "screenwriter" brother, Petri Dish fuses hard science with a freewheeling and madcap conversational style.

Cannabinoids, Plague, Cats, the dreaded Candiru, and the even more dreaded Covid-19: all these and more are dissected with intellect and irreverence, dropping every week.

So reject ignorance. Join the Scientific Revolution. Join Petri Dish.
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Ep. 67 Stress: The Seahorse in Your Brain
2020... The Year of Stress... We're past the halfway point in spooky October everyone, hope you've been having a nice time! This episode is part three of our series on stress -- we covered stress hormones and the parts of your body that make them in the past two episodes, so this episode is all about the BRAIN! The hippocampus! The amygdala! The medial prefrontal cortex! WTF are they doing and why does my brain want me to feel this way? This episode has a promo for Plants and Pipettes, a podcast about the molecular biology of plants, those goofy things! Check them out at @plantspipettes on twitter and at https://plantsandpipettes.com/. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939226/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637449/ https://www.frontiersin.org/articles/10.3389/fnins.2016.00224/full https://www.nature.com/articles/s41598-019-43733-2 https://www.neuroscientificallychallenged.com/blog/know-your-brain-amygdala https://www.intechopen.com/books/the-amygdala-where-emotions-shape-perception-learning-and-memories/the-key-role-of-the-amygdala-in-stress https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753223/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580281/ https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00006.2019 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562704/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946139/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535428/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656452/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028159/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564342/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972338/
51:46
October 19, 2020
[CORRECTED] Ep. 66 Stress: The HPA Axis of Evil
This is a corrected version of the episode! The audio from the last release was all messed up! Sorry about the mistake! Are y'all done feeling stressed yet? No? Well neither are we! We continue our discussion from last episode, moving on to the stuff that actually makes the stress hormone, the HPA axis! What does the hypothalamus-pituitary-adrenal axis do and how does it work? Also, we discuss what the science is behind stress vis-a-vis hair loss and hair greying! This episode has a promo for Online Warriors, a podcast where we discuss the latest in gaming, movies, entertainment, & sports. Check them out on twitter: @OnlineWarriors1 Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.hopkinsmedicine.org/health/conditions-and-diseases/adrenal-glands https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860392/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860380/ https://www.capillus.com/blogs/all/understanding-hair-growth-stages https://www.health.harvard.edu/a_to_z/telogen-effluvium-a-to-z https://www.medscape.com/viewarticle/759931_2 https://www.frontiersin.org/articles/10.3389/fncel.2019.00054/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514792/ https://www.health.harvard.edu/blog/hair-turn-gray-2017091812226 https://www.nature.com/articles/s41586-020-1935-3
35:15
October 12, 2020
Ep. 65 We're All So Freakin' Stressed!
WE'RE SO STRESSED 2020! But what is stress, in a biological level? And how does it related to "feeling stressed"? In this episode we dive into biological stress, both physiological and psychosocial, and talk about some of the stress hormones that course through your blood when you're feeling stressed out! Tune in next episode to learn about where these stress hormones are made and the start of our dive into the neuroscience of stress. This episode has a promo for Podcast Review Day, which is the 8th of every month! Join us in reviewing the podcasts you enjoy wherever you listen and at podchaser.com! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.hindawi.com/journals/ijcb/2010/214074/ https://www.nature.com/articles/s41580-018-0068-0 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204665 https://pubmed.ncbi.nlm.nih.gov/17578761/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475279/ https://academic.oup.com/edrv/article/38/1/3/2959892 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959222/ https://www.healthline.com/health/epinephrine-vs-norepinephrine https://www.sciencedirect.com/science/article/pii/S009130220700057X?via%3Dihub
39:16
October 5, 2020
Ep. 64 The BBB2: The Crack in the Wall
Last episode introduced the blood brain barrier; it is a lot like a bouncer for the exclusive dance club that is your brain, keeping all the randos out. But this week we get into some of the details on diseases and drugs and their impact on the blood brain barrier. Also, sometimes we WANT drugs to get into the brain, so how can we get around this BBB? This episode has a promo for Lit Gaming Area Podcast! This is a gaming news and discussion podcast! Check them out at  @litgamingarena on twitter! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.ahajournals.org/doi/10.1161/01.HYP.2.6.809 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733101/ https://www.ncbi.nlm.nih.gov/books/NBK554499/ https://science.sciencemag.org/content/366/6472/1448?rss=1 https://journals.sagepub.com/doi/full/10.1177/0271678X15616978 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320935/ https://onlinelibrary.wiley.com/doi/full/10.1002/ana.24271 https://www.sciencedirect.com/science/article/pii/S014976341730773X https://www.nature.com/articles/s41568-019-0205-x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169949/ https://www.nih.gov/news-events/nih-research-matters/how-cancer-vesicles-breach-blood-brain-barrier https://www.frontiersin.org/articles/10.3389/fneng.2013.00007/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751454/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694729/ https://www.nature.com/articles/d41573-020-00102-3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337067/ https://www.nature.com/articles/s41598-019-42272-0 https://pubmed.ncbi.nlm.nih.gov/17472409/ https://www.tandfonline.com/doi/full/10.1080/17425247.2018.1429401 https://www.pnas.org/content/114/1/E75 https://www.tandfonline.com/doi/full/10.1080/17425247.2020.1698544
1:03:54
September 28, 2020
Ep. 63 The Brain's Bouncer: The Blood Brain Barrier
We did a twitter poll and the people have spoken! You folks want to hear about the "Blood Brain Barrier"! But what is it, besides great alliteration?! The blood brain barrier is a lot like a bouncer for the exclusive dance club that is your brain -- but who is allowed in? How does one get in? And on a cellular and protein level, who are the actual bouncers that keep us out? Next week we will get into some of the details on diseases and drugs and their impact on the blood brain barrier, so tune in next week too! This episode has a promo for Everything I Learned From Movies Podcast! This is a movie and beer discussion podcast! Check them out at @eilfmovies on twitter! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.tandfonline.com/doi/pdf/10.3109/13813452109146211 https://onlinelibrary.wiley.com/doi/full/10.1002/glia.20642 https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.1986.tb27136.x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267212/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664562/ https://pubmed.ncbi.nlm.nih.gov/11282155/ https://www.nature.com/articles/s41598-018-37367-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697631/ https://pubmed.ncbi.nlm.nih.gov/15717053/ https://www.nature.com/articles/s41366-018-0221-z https://www.nature.com/articles/1301452 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796930/ https://www.ncbi.nlm.nih.gov/books/NBK27998/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494002/ https://www.frontiersin.org/articles/10.3389/fonc.2018.00239/full https://pubmed.ncbi.nlm.nih.gov/20093161/ https://www.ncbi.nlm.nih.gov/books/NBK53086/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292164/ https://www.sciencedirect.com/science/article/pii/S0301008215300691
57:32
September 21, 2020
Ep. 62 Bleedin' Gums and Vitamin C
We all know *about* vitamin C but... what actually IS vitamin C? And what does it even do in your body? How can being deficient in vitamin C make pirates bleed out of their gums and have their teeth fall out? Also, can vitamin C cure cancer? Find out some of this stuff, tune in! This episode is sponsored in part by Vaer Watches, which you can visit at  https://www.vaerwatches.com/. Currently you can get 15% off with the code PODGO15, check it out! This episode has a promo for Bald Scientist Podcast! This guy is a real legend of a scientist, and he's bringing all sorts of great science and life lessons to your ears! Check him out at https://baldscientist.com/ ! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://apps.who.int/iris/bitstream/handle/10665/42716/9241546123.pdf https://www.jstor.org/stable/pdf/20094480.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145266/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901412 https://www.ncbi.nlm.nih.gov/books/NBK493187/ https://www.ncbi.nlm.nih.gov/books/NBK493187/ https://hekint.org/documents/sailors_scurvy-final.pdf https://www.alcademics.com/2018/11/historical-info-about-scurvy-and-the-confusion-between-lemons-and-limes.html https://www.mdpi.com/2072-6643/9/4/339 https://www.mdpi.com/2072-6643/9/11/1211 https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000980.pub4/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039380/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725835/ https://jamanetwork.com/journals/jama/fullarticle/2752063 https://jamanetwork.com/journals/jama/fullarticle/2761631 https://jamanetwork.com/journals/jama/fullarticle/2769467 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725125/ https://www.mdpi.com/2072-6643/9/9/960 https://www.nature.com/articles/s41568-019-0135-7
1:08:03
September 14, 2020
Ep. 61 Measles, or, Why People are Dumb
Measles! Super contagious, very tricky, no real treatments, can cause IMMUNE AMNESIA! But hey, we have a vaccine, so this disease should be history, right? Well, definitely not yet! Learn more about this disease on this week's episode! This episode is sponsored in part by Vaer Watches, which you can visit at  https://www.vaerwatches.com/  to purchase beautiful curated photographs. Currently you can get 15% off with the code PODGO15, check it out! This episode has a promo for Podcast Review Day! If you like us, please take some time today to rate and review us (and other pods!) in the app you're using, on the iTunes store, and/or at podchaser.com! Rating and reviewing us helps us reach other people! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.cdc.gov/vaccines/pubs/pinkbook/meas.html https://www.ninds.nih.gov/Disorders/All-Disorders/Subacute-Sclerosing-Panencephalitis-Information-Page https://www.who.int/news-room/fact-sheets/detail/measles https://europepmc.org/article/med/28757186 https://academic.oup.com/jid/article/204/suppl_1/S47/2192303#90226645 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838858 https://www.sciencemag.org/news/2015/01/what-does-measles-actually-do https://science.sciencemag.org/content/366/6465/599 https://www.nature.com/articles/d41586-019-03324-7 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074295/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605051/pdf/yjbm00613-0088.pdf https://www.cdc.gov/measles/about/history.html https://www.historyofvaccines.org/content/blog/brief-history-measles https://www.who.int/vaccine_safety/initiative/tools/MMR_vaccine_rates_information_sheet.pdf?ua=1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007870/ https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Febrile-Seizures-Fact-Sheet https://www.cdc.gov/vaccinesafety/vaccines/mmr/mmr-studies.html https://www.mdpi.com/1999-4915/11/11/1017/htm
59:50
September 7, 2020
Ep. 60 Plastics Plastics PLASTICS!
Plastics! So useful! But also filling up our landfills and gunking up our oceans! What are microplastics? Are they bad for human health and/or the environment? What even ARE plastics? And are there any ways we can recycle or otherwise deal with plastic waste better than we are right now? Check out the episode! This episode is sponsored in part by Vaer Watches, which you can visit at  https://www.vaerwatches.com/  to purchase beautiful curated photographs. Currently you can get 15% off with the code PODGO15, check it out! This episode has a promo for For Your Reference, a podcast discusses music from all genres!  Check them out on Twitter @Infectious_Pod, at https://linktr.ee/Infectiousgroovepodcast, and wherever you get your podcasts. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://pubs.rsc.org/en/content/articlehtml/2017/cs/c7cs00149e https://www.sciencedirect.com/science/article/pii/S0165993618305144 https://www.annualreviews.org/doi/full/10.1146/annurev-marine-010419-010633 https://iopscience.iop.org/article/10.1088/1748-9326/ab59ca/meta https://pubs.acs.org/doi/full/10.1021/acs.est.9b01339 https://www.cambridge.org/core/journals/journal-of-developmental-origins-of-health-and-disease/article/transgenerational-effects-of-maternal-bisphenol-a-exposure-on-offspring-metabolic-health/A578D5273CC8124C922C081F4FFC80B9 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191934 https://www.sciencedirect.com/science/article/pii/S0015028216626249 https://www.cdc.gov/biomonitoring/Phthalates_FactSheet.html https://www.sciencedirect.com/science/article/abs/pii/S0924224417303898 https://www.sciencedirect.com/science/article/pii/S0147651319313971 https://pubs.acs.org/doi/10.1021/es504038a https://pubs.acs.org/doi/10.1021/acs.est.5b02661 https://pubs.acs.org/doi/10.1021/acs.est.5b02663 https://pubs.acs.org/doi/10.1021/acs.est.8b02301 https://pubs.acs.org/doi/10.1021/es801010e https://www.nature.com/articles/s41557-019-0249-2
1:03:16
August 31, 2020
Ep. 59 Fungus: The Good, The Bad, and The Zombie
This week we're doing our second episode about Fungi! Last week we talked about what fungi even are in a broad sense. This week we cover symbiotic and pathogenic fungi, like the famous Cordyceps fungi! This episode is sponsored in part by Vaer Watches, which you can visit at  https://www.vaerwatches.com/  to purchase beautiful curated photographs. Currently you can get 15% off with the code PODGO15, check it out! Btw near the end of the episode Sean mentions carpenter ants farming fungi -- they don't. That's more like leafcutter ants. Carpenter ants *do* farm aphids, but that shit is different. This episode has a promo for For Your Reference, a podcast that reviews tv shows and movies!  Check them out on Twitter  @ForYourRefPod, at https://fyrpodcast.com/, and wherever you get your podcasts. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.13371 https://www.sciencedirect.com/science/article/pii/0303264775900234 https://www.nature.com/articles/s41598-018-28920-x https://www.mdpi.com/2076-2607/8/2/230 https://link.springer.com/content/pdf/10.1007/s00572-020-00948-w.pdf https://www.nature.com/articles/s41598-017-12731-7 https://www.frontiersin.org/articles/10.3389/fpls.2019.01068/full http://www.bbc.com/earth/story/20141111-plants-have-a-hidden-internet https://www.sciencefocus.com/nature/mycorrhizal-networks-wood-wide-web/ https://www.sciencedirect.com/science/article/abs/pii/S1749461312000048 https://link.springer.com/chapter/10.1007/978-3-319-75596-0_10 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497361/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187645/ https://www.nature.com/articles/s41467-019-08809-7 https://www.sciencedirect.com/science/article/pii/S0953756209812239?via%3Dihub https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/ https://link.springer.com/chapter/10.1007/978-1-4615-9846-6_2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150023/ https://link.springer.com/article/10.1007/s13225-019-00430-9
58:18
August 24, 2020
Ep. 58 Fungus: What Even Is It?
This week we're talking about Fungi! They used to be grouped in with plants, then got their own Kingdom... But what do we think about them now? What even are fungi? How can a group contain both little yeasts used for baking and mushrooms that can get you high? And how have we used them to make huge leaps forward in biological sciences? Next week we'll cover symbiotic and pathogenic fungi, like the famous Cordyceps fungi! This episode is sponsored in part by The Galry, which you can visit at thegalry.com to purchase beautiful curated photographs. Currently you can get 15% off with the code 15OFF, check it out! This episode has a promo for Culture Quest, a podcast about all kinds of pop culture, from tv shows to movies to albums!  Check them out on Twitter @CQ_Podcast, at  https://sites.google.com/view/the-culture-quest/home, and wherever you get your podcasts. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://science.sciencemag.org/content/163/3863/150 https://www.pnas.org/content/pnas/87/12/4576.full.pdf https://www.sciencedirect.com/science/article/abs/pii/S0966842X11001740 https://www.nature.com/articles/nrmicro.2017.133.pdf?origin=ppub https://www.sciencedirect.com/science/article/pii/S0169534719302575 https://onlinelibrary.wiley.com/doi/full/10.1111/brv.12550 https://academic.oup.com/femsec/article/80/3/735/445744 https://academic.oup.com/femsre/article/41/6/941/4569254#111103971 https://www.sciencemag.org/news/2016/03/iron-eating-fungus-disintegrates-rocks-acid-and-cellular-knives https://www.nature.com/articles/39493 https://www.frontiersin.org/articles/10.3389/fmicb.2018.01392/full https://www.cnet.com/news/fungi-found-in-chernobyl-feeds-on-radiation-report-says/ https://link.springer.com/chapter/10.1007/978-3-030-19030-9_10 https://hub.jhu.edu/2019/11/01/melanin-space-study/ https://aem.asm.org/content/77/17/6076
52:48
August 17, 2020
Ep. 57 Autoimmune: Why and What Can We Do?
Howdy y'all! Today we're releasing our final episode on autoimmune disorders! If you haven't already, we highly recommend you check out our episodes on the immune system (Episodes 36 and 38) for useful background information that will help you understand this episode, and also check out our previous couple of episodes on examples of chronic inflammatory disorders and autoimmune diseases! This episode is sponsored in part by The Galry, which you can visit at thegalry.com to purchase beautiful curated photographs. Currently you can get 15% off with the code 15OFF, check it out! This episode has a promo for Book Retorts, a podcast where one host tries to explain some weird media -- book tv movie -- to their cohost! Check them out on twitter @bookretorts,  https://www.bookretorts.com/ , and wherever you get your podcasts. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC508890/ https://www.ncbi.nlm.nih.gov/pubmed/25198367 https://www.ncbi.nlm.nih.gov/books/NBK507863/ https://www.sciencedirect.com/science/article/pii/S0029646518300409?via%3Dihub https://www.ncbi.nlm.nih.gov/pubmed/24120737 https://www.frontiersin.org/articles/10.3389/fimmu.2019.00148/full
52:46
August 10, 2020
Ep. 56 Autoimmune: When Your Body Auto-Attacks You
Ahoy-hoy! Today we're releasing an episode on autoimmune disorders like lupus and MS! What is going on in these diseases where your adaptive immune system starts attacking you? If you haven't already, we highly recommend you check out our episodes on the immune system (Episodes 36 and 38) for useful background information that will help you understand this episode and some of our upcoming episodes! Next episode will be about the molecular reasons behind autoimmune disorders and how we treat them. This episode is sponsored in part by The Galry, which you can visit at thegalry.com to purchase beautiful curated photographs. Currently you can get 15% off with the code 15OFF, check it out! This episode has a promo for Curiosity Killed the Rat, another groovy science podcast! Check them out on twitter @CuriosityRat and wherever you get your podcasts. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.nejm.org/doi/10.1056/NEJMra1100030 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753361/ https://www.nature.com/articles/nri3871 https://www.pnas.org/content/114/40/10719.short https://www.sciencedirect.com/science/article/pii/S0165572817305660 https://www.sciencedirect.com/science/article/pii/S1568997215000282?via%3Dihub https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130012/ https://www.hopkinsarthritis.org/arthritis-info/rheumatoid-arthritis/ra-pathophysiology-2/#disease https://www.nature.com/articles/nrrheum.2018.10 https://ghr.nlm.nih.gov/condition/systemic-lupus-erythematosus#statistics https://link.springer.com/article/10.1007/s11926-016-0571-2 https://onlinelibrary.wiley.com/doi/full/10.1111/joim.12529 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144759/ https://stm.sciencemag.org/content/11/522/eaax1159 https://www.nature.com/articles/s41467-019-13756-4 https://www.tandfonline.com/doi/full/10.1586/1744666X.2013.811052
53:31
August 3, 2020
Ep. 55 Chronic Inflammatory Disorders
Hey folks! Today we're releasing an episode on chronic inflammatory disorders like osteoarthritis! If you haven't already, we highly recommend you check out our episodes on the immune system (Episodes 36 and 38) for useful background information that will help you understand this episode and some of our upcoming episodes! This episode is sponsored in part by The Galry, which you can visit at www.thegalry.com to purchase beautiful curated photographs. Currently you can get 15% off with the code 15OFF, check it out! This episode has a promo for Sips, Suds & Smokes, a podcast that rates, reviews, and discusses all kinds of tasty drinks and smoked meats and more! Check them out on twitter  @sipssudssmokes and wherever you get your podcasts. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.nature.com/articles/s41577-019-0215-7 https://www.nature.com/articles/nri3261 https://link.springer.com/article/10.1007%2Fs00281-018-0670-4 https://science.sciencemag.org/content/336/6086/1314.full https://www.frontiersin.org/articles/10.3389/fmed.2018.00032/full https://www.nature.com/articles/nrrheum.2016.136 https://link.springer.com/article/10.1007/s11926-017-0672-6 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465583/ https://www.sciencedirect.com/science/article/pii/S1359610118301199
35:58
July 30, 2020
Ep. 54 Bacteria's Weapons of War Part 2
Hey folks! Last week we divided our episode in two, and here is the second part of bacteria's weapons of war! This episode continues our coverage about the little biological weapons bacteria have evolved to wage war on other bacteria and on eukaryotic cells as well! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.sciencedirect.com/science/article/pii/S0092867418301119 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140923/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176049/ https://www.cell.com/trends/microbiology/comments/S0966-842X(18)30022-2 https://www.frontiersin.org/articles/10.3389/fpls.2014.00155/full https://www.frontiersin.org/articles/10.3389/fmicb.2019.01078/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC127815/ https://www.frontiersin.org/articles/10.3389/fmicb.2019.01965/full https://www.nature.com/articles/s41564-018-0277-5 https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000720 https://www.sciencedirect.com/science/article/pii/S096289241730082X https://www.sciencedirect.com/science/article/pii/S2090123219300815 https://www.pnas.org/content/116/46/23292.short https://www.pnas.org/content/106/11/4154.full https://www.nature.com/articles/s41598-018-33800-5 https://www.pnas.org/content/111/33/12127.short https://academic.oup.com/gbe/article/11/10/2941/5575074 https://www.nature.com/articles/s41579-018-0070-8 https://www.sciencedirect.com/science/article/abs/pii/S0966842X2030007X https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616380/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034461/ https://www.sciencedirect.com/science/article/pii/S2090123219300815
26:29
July 27, 2020
Ep. 53 Bacteria's Weapons of War Part 1
Hey folks! Somewhat short episode this week! We originally intended to release the complete episode, but we've divided it in two because we're dealing with a little bit of pandemic stuff but want to keep delivering content! Anyway, this episode is about the little biological weapons bacteria have evolved to wage war on other bacteria and on eukaryotic cells as well! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.sciencedirect.com/science/article/pii/S0092867418301119 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140923/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176049/ https://www.cell.com/trends/microbiology/comments/S0966-842X(18)30022-2 https://www.frontiersin.org/articles/10.3389/fpls.2014.00155/full https://www.frontiersin.org/articles/10.3389/fmicb.2019.01078/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC127815/ https://www.frontiersin.org/articles/10.3389/fmicb.2019.01965/full https://www.nature.com/articles/s41564-018-0277-5 https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000720 https://www.sciencedirect.com/science/article/pii/S096289241730082X https://www.sciencedirect.com/science/article/pii/S2090123219300815 https://www.pnas.org/content/116/46/23292.short https://www.pnas.org/content/106/11/4154.full https://www.nature.com/articles/s41598-018-33800-5 https://www.pnas.org/content/111/33/12127.short https://academic.oup.com/gbe/article/11/10/2941/5575074 https://www.nature.com/articles/s41579-018-0070-8 https://www.sciencedirect.com/science/article/abs/pii/S0966842X2030007X https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616380/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034461/ https://www.sciencedirect.com/science/article/pii/S2090123219300815
23:46
July 20, 2020
Ep. 52 What Even Are Clinical Trials?
Hi Everyone, it is still pandemic and you should still stay safe out there. This week Sean and Nathan discuss clinical trials! You might be hearing a lot about clinical trials in the news (especially because of the pandemic), but not all clinical trials are well designed. Check out this episode to help you develop a critical eye for those clinical trial results. This episode features a promo for  Grand Rapidians Play Video Games , a podcast that reviews and discusses beer, games, and other podcasts! Check them out on twitter  @grand_video Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.fda.gov/patients/clinical-trials-what-patients-need-know/what-are-different-types-clinical-research https://www.ashp.org/-/media/store%20files/p2418-sample-chapter-1.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083073/ https://www.fda.gov/patients/drug-development-process/step-3-clinical-research#phases https://www.ncbi.nlm.nih.gov/pubmed/24451821 https://www.cancer.gov/publications/dictionaries/cancer-terms/def/phase-iv-clinical-trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434767/
1:07:21
July 13, 2020
Ep. 51.5 Racism and IQ
Hi Everyone, hope you are all staying safe during this pandemic. This is the second half of our final episode of this racism series -- we talked so much about racist experiments in episode 51 that we ran out of time to talk about the history and issues with IQ. This episode features a promo for Play Comics, a podcast that looks at the intersection between comic book-inspired video games and the source material they are drawn from. Check them out on twitter @playcomicscast and at  http://playcomics.com/ . Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.businessinsider.com/iq-tests-dark-history-finally-being-used-for-good-2017-10 https://www.pnas.org/content/113/47/13354.full https://www.sciencedaily.com/releases/2007/04/070424204519.htm https://www.sciencedirect.com/science/article/pii/S0191886920301045
37:04
July 10, 2020
Ep. 51 Racist Experiments
Hi Everyone, hope you are all staying safe during this pandemic. We are continuing our series on the long intertwining history of race, racism, and science. In this episode, the third of four*, we discuss some specific examples of racist scientific misconduct: things like the Tuskegee Experiment and the treatment of Henrietta Lacks and her family. *We went so long on this episode that we split it in two, with the second part on Racism and IQ coming out on Friday, so look forward to hearing Sean and Nathan rant about that shit for like 40 minutes. This episode features a promo for Podcast Review Day, a day to review your favorite podcasts on  https://www.podchaser.com/ or Apple Podcasts or wherever! It happens on the 8th of every month. Learn more on twitter @PodRevDay or at  https://www.stephfuccio.com/podrevday.html Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Reach out if you'd like to talk things through. Stay safe out there everyone! References: https://www.wired.com/story/the-speculum-finally-gets-a-modern-redesign/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563360/ https://www.theatlantic.com/health/archive/2018/04/j-marion-sims/558248 https://www.cdc.gov/tuskegee/timeline.htm https://en.wikipedia.org/wiki/Terre_Haute_prison_experiments
53:38
July 6, 2020
Ep. 50 Eugenics and Human Genetics
Hi Everyone, hope you are all staying safe during this pandemic. For our 50th full episode, we are continuing our series on the long intertwining history of race, racism, and science. In this episode, the second of three, we discuss racist science in the 20th and 21st century by focusing on eugenics and human genetics. Next time we will talk about specific examples of racist scientific misconduct and racism in IQ. This episode features a promo for Planthropology, a science podcast centered around plants! Find them on twitter at @Planthropology_ and  https://www.planthropologypod.com/ Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Reach out if you'd like to talk things through. Stay safe out there everyone! References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973272/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757926/ https://en.wikipedia.org/wiki/James_Watson#Comments_on_race https://www.nytimes.com/2018/03/23/opinion/sunday/genetics-race.html https://www.annualreviews.org/doi/full/10.1146/annurev-soc-060116-053403#_i23 https://www.vox.com/2018/4/10/17182692/bell-curve-charles-murray-policy-wrong https://www.brookings.edu/articles/does-the-bell-curve-ring-true-a-closer-look-at-a-grim-portrait-of-american-society/#:~:text=While%20critics%20of%20The%20Bell,difference%20and%20the%20argument%20that
1:09:08
June 29, 2020
Ep. 49 Racism in Science
Hi Everyone, hope you are all staying safe during this pandemic. The murder of Black people like Breonna Taylor and George Floyd has led to a lot of discussion here at Petri Dish about what we could do with our platform. We decided one of the things we could do was inform our listeners about the long intertwining history of race, racism, and science. In this episode, the first of three, we discuss the early history of modern conceptions of race, going back to the 17th century. Next time we will be discussing eugenics and human genetics. This episode features a promo for SipNSci, a comedic science podcast centered around Black scientists, some drinks, and a whole lot of science. Find them at @SipNScipod. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Reach out if you'd like to talk things through. Stay safe out there everyone! References: https://onlinelibrary.wiley.com/doi/pdf/10.1002/9780470753514.fmatter https://www.tandfonline.com/doi/full/10.1080/00033790.2013.785022 https://www.jstor.org/stable/pdf/30053821.pdf?refreqid=excelsior%3Ae5d7d92922ed4be635c43acbfa3a2332 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151154/ https://www.encyclopedia.com/science/encyclopedias-almanacs-transcripts-and-maps/johann-blumenbach-and-classification-human-races https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001071 https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2007008
52:05
June 22, 2020
Ep. 48 Sun and Skin
On this, the final skin episode of our four-part (!) series, Sean and Nathan speak again with skin scientist Matilde Miranda about skin aging and the affect sunlight has on your skin! Learn about what SPF and UV Index means, the different kinds of UV light, and how to pick a nice sunscreen to reduce your chances of getting skin cancer. Featuring a promo for an upcoming podcast Talking Bugs, an entomology podcast! check it out on twitter @SixLeggedAggie and  https://sixleggedaggie.com/ Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Reach out if you'd like to talk things through. Stay safe out there everyone! References: https://www.tandfonline.com/doi/full/10.1586/17469872.2.6.753 https://seer.cancer.gov/statfacts/html/melan.html http://gco.iarc.fr/today/data/factsheets/cancers/16-Melanoma-of-skin-fact-sheet.pdf http://gco.iarc.fr/today/data/factsheets/cancers/17-Non-melanoma-skin-cancer-fact-sheet.pdf https://onlinelibrary.wiley.com/doi/full/10.1111/phpp.12214 https://pubs.acs.org/doi/full/10.1021/acs.jpclett.5b00417 https://www.consumerreports.org/cro/magazine/2015/05/what-does-spf-stand-for/index.htm https://agupubs.onlinelibrary.wiley.com/doi/full/10.1029/2004RG000155 https://www.epa.gov/sites/production/files/documents/uviguide.pdf https://www.ncbi.nlm.nih.gov/pubmed/28718005 https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective https://www.ewg.org/sunscreen/report/the-trouble-with-sunscreen-chemicals/
53:12
June 15, 2020
Ep. 47 Science of Trippin' Balls
This week Nathan and Sean talk about psychedelic drugs, specifically classical psychedelics like psilocybin and LSD. How do they work? What do they actually do to your brain? Can they be repurposed for more than making you see crazy stuff? Listen in! Stay safe out there, everyone. Featuring a promo for The Unexceptionals, an interview podcast! Check it out on twitter @_unexceptionals Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Support us for as little as $1 a month at patreon.com/petridish. Thanks! References: https://www.cell.com/current-biology/pdf/S0960-9822(11)01198-5.pdf https://www.ncbi.nlm.nih.gov/pubmed/22750845 https://journals.physiology.org/doi/full/10.1152/jn.1999.82.6.2989 https://www.sciencedirect.com/science/article/pii/S0168010211020074 https://www.sciencedirect.com/science/article/pii/S0301051111003164 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1409828/ https://www.sciencedirect.com/science/article/abs/pii/S0028390812002651 https://www.sciencedirect.com/science/article/pii/S0896627307000281 https://www.frontiersin.org/articles/10.3389/fphar.2015.00225/full https://journals.sagepub.com/doi/full/10.1177/0269881116675513 https://jamanetwork.com/journals/jamapsychiatry/article-abstract/210962 https://journals.sagepub.com/doi/full/10.1177/0269881116675512 https://www.sciencedirect.com/science/article/pii/S2215036616300657 https://journals.sagepub.com/doi/abs/10.1177/0269881114565144 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086777/ https://journals.lww.com/psychopharmacology/FullText/2016/02000/Antidepressant_Effects_of_a_Single_Dose_of.13.aspx https://www.nature.com/articles/npp201784 https://www.sciencedirect.com/science/article/abs/pii/S0924977X15000097
49:41
June 8, 2020
Ep. 46.5 Bonus Minisode: COVID and Kawasaki
Take care of yourselves out there, everyone. Racism is real and Black people have suffered the brutality of racist systems for their entire lives. This week's bonus episode is about Kawasaki Disease and the atypical Kawasaki that appears to be manifesting in children during this COVID-19 pandemic. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Reach out if you'd like to talk things through. References: https://pediatrics.aappublications.org/content/early/2020/03/16/peds.2020-0702.1 https://onlinelibrary.wiley.com/doi/full/10.1111/apa.15270 https://www.medrxiv.org/content/10.1101/2020.03.03.20028423v3 https://www.medrxiv.org/content/10.1101/2020.05.11.20098459v1 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31103-X/fulltext https://www.onlinejacc.org/content/67/14/1738.abstract https://link.springer.com/article/10.1007/s11926-020-0882-1 https://www.sciencedirect.com/science/article/pii/B9780124202191000045 https://heart.bmj.com/content/106/6/411.abstract https://www.onlinejacc.org/content/28/1/253.abstract https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1809480/ https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011188.pub2/full https://link.springer.com/article/10.1007/s00431-017-2937-5 https://journals.lww.com/jclinrheum/Citation/2020/03000/Severe_Late_Onset_Kawasaki_Disease_Successfully.19.aspx https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720480/ https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31103-X/fulltext https://www.medrxiv.org/content/10.1101/2020.05.10.20097394v1.full.pdf https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(20)30137-5/fulltext https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31094-1/fulltext References got truncated, check on patreon for the full list.
34:06
June 5, 2020
Ep. 46 Science of Sick
What actually happens when you get infected with something? What are the steps your body goes through to protect you? Why do so many illnesses have "flu-like" symptoms? Find out this week as Sean and Nathan dive into the SCIENCE OF SICK(ness)! We recorded this episode a while ago, so it does not make reference to current (US) events. We here at Petri Dish support protesters and the cause they represent -- an end to racial discrimination against Black people, an end to police brutality, and a restructuring of the USA to a more equitable and equal society. Black lives matter! Thank you everyone, for listening. Featuring a promo for Jolly Green Scientists, an upcoming science podcast! Check out the hosts on twitter @SixLeggedAggie and @Planthropology_ Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Support us for as little as $1 a month at patreon.com/petridish. Thanks! References: https://pubs.rsc.org/en/content/articlehtml/2018/mt/c7mt00341b https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172236 https://www.pnas.org/content/114/26/6806.short https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981609/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047205/ https://science.sciencemag.org/content/353/6306/1393 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786079/ https://link.springer.com/chapter/10.1007/978-3-319-92336-9_9 https://www.sciencedirect.com/science/article/abs/pii/S1074761318304953?via%3Dihub https://www.sciencedirect.com/science/article/pii/S147330990570270X https://link.springer.com/chapter/10.1007/978-3-7643-9912-2_2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378761/ https://www.ncbi.nlm.nih.gov/pubmed/23356301/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553670/ https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-019-1120-0 https://www.atsjournals.org/doi/full/10.1164/rccm.200805-670OC https://link.springer.com/article/10.1007/s00408-015-9808-5
46:45
June 1, 2020
Ep. 45 Some Super Special Cephalopods
This week we talk about some specific cephalopods and how weird/cool they are! Giant squids! Blue-ringed octopuses! Bigfin squids, argonauts, nautiloids, and more! Get your fill of these funky folks under the sea! Featuring a promo for Thorndale, an actual play podcast! Check them out at  https://www.thornvalepodcast.com/ and on twitter  @ThornvaleCast Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Support us for as little as $1 a month at patreon.com/petridish. Thanks! References: https://blogs.scientificamerican.com/octopus-chronicles/unusual-offshore-octopods-the-weapon-wielding-blanket-octopus-video/ https://jeb.biologists.org/content/jexbio/211/12/1992.full.pdf https://www.scientificamerican.com/article/can-squid-fly/ https://www.nytimes.com/1997/10/21/science/when-giant-squids-mate-it-s-a-stab-in-the-dark.html https://royalsocietypublishing.org/doi/full/10.1098/rsbl.2011.0680 https://www.youtube.com/watch?v=G4U0vG2bxy0 https://link.springer.com/article/10.1007/s00227-003-1285-3
42:40
May 25, 2020
Ep. 44 Octopuseses: Ink, Camo, and Smarts
This episode is about cephalopods! Octopuses, squids, cuttlefish! All the jabronis! This is actually a two-parter. In this episode we're talking about cephalopod blood, eyes, ink, camo, and intelligence! Next time we are going to be talking about specific cephalopods that we think are particularly weird and cool! Featuring a promo for Planthropology, a podcast about plants! Check them out on twitter @planthropology_ and online at planthropologypod.com Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Support us for as little as $1 a month at patreon.com/petridish. Thanks! References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730353/ https://www.nature.com/articles/srep04256 https://jeb.biologists.org/content/212/14/2133 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052311/ https://jeb.biologists.org/content/207/11/1759 https://www.nature.com/scitable/topicpage/cephalopod-camouflage-cells-and-organs-of-the-144048968/ https://www.pnas.org/content/111/36/12998.full https://science.sciencemag.org/content/358/6360/210 https://www.frontiersin.org/articles/10.3389/fpsyg.2019.01686/full https://en.wikipedia.org/wiki/Squid_giant_axon https://www.oxfordhandbooks.com/view/10.1093/oxfordhb/9780190456757.001.0001/oxfordhb-9780190456757-e-29 https://oxfordre.com/neuroscience/view/10.1093/acrefore/9780190264086.001.0001/acrefore-9780190264086-e-181 https://www.pnas.org/content/117/15/8524.full https://www.sciencedirect.com/science/article/pii/S0169534718302672
51:52
May 18, 2020
Ep. 43 Prions: Mad Cows and Mad Proteins
This episode is about the causative agent for mad cow disease, scrapie, and Creutzfeldt-Jakob -- prions! It's not a bacteria, it's not a fungus, it isn't even a virus! No, it is a little protein encoded in our own genome! Find out how there can be an infectious disease caused by a misfolded protein. Featuring a promo for Lit Gaming Arena Podcast! Check them out on twitter @litgamingarena and online at  https://litgamingarena.com/ Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. Support us for as little as $1 a month at patreon.com/petridish. Thanks! References: https://cshperspectives.cshlp.org/content/3/1/a006833.full https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0375-5 https://link.springer.com/article/10.1007/s12035-019-1510-9 https://cshperspectives.cshlp.org/content/9/1/a023671.full https://onlinelibrary.wiley.com/doi/full/10.1111/sji.12854 https://rupress.org/jem/article/79/2/137/4753/STUDIES-ON-THE-CHEMICAL-NATURE-OF-THE-SUBSTANCE https://science.sciencemag.org/content/216/4542/136.abstract https://www.nature.com/articles/s41576-018-0011-4 https://www.tandfonline.com/doi/full/10.1080/19336896.2019.1704612 https://www.nature.com/articles/s41598-018-36700-w https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaa078/5821469 https://www.nature.com/articles/nature20415 https://neurolrespract.biomedcentral.com/articles/10.1186/s42466-019-0039-8 https://www.cell.com/trends/neurosciences/pdf/S0166-2236(10)00055-X.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959295/ https://www.jbc.org/content/294/18/7128.full https://www.sciencedirect.com/science/article/abs/pii/S0962892413000111 https://www.nature.com/articles/mp201784 https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1007283
50:27
May 11, 2020
Ep. 42 A Conspiracy of Ravens
Ravens, crows, and other corvids have held a special place in the human imagination for centuries, and deservedly so! In this episode, we discuss ANIMAL INTELLIGENCE in the context of ravens and crows. We talk about tool-making, inductive reasoning, and convergent evolution of counting! Funky stuff! Learn about these cool birds! Special shoutout to Dr. Swift (twitter: @corvidresearch), her twitter and blog inspired us to do this episode! Featuring a promo for the podcast Ignorance Was Bliss, check it out on twitter @IWBpodcast and  https://iwbpodcast.com/ Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://link.springer.com/article/10.1007/s10071-003-0200-0 https://www.nature.com/articles/414707a https://science.sciencemag.org/content/297/5583/981 https://link.springer.com/article/10.1007/s10071-016-1016-z https://www.nature.com/articles/s41598-018-33458-z https://royalsocietypublishing.org/doi/full/10.1098/rspb.2010.0285 https://royalsocietypublishing.org/doi/10.1098/rspb.2018.2332 https://www.nature.com/articles/ncomms10506 https://www.jneurosci.org/content/27/36/9535 https://www.jneurosci.org/content/27/22/5986 https://www.pnas.org/content/112/25/7827 https://www.sciencedirect.com/science/article/pii/S0896627302011443
59:00
May 4, 2020
Ep. 41 Bats Part 2: They're Good!
In part 1 we talked about bat diseases and bat immune system stuff, but this episode is is all about how bats are cool! Bat pollination! Bat pooping! Bat bros! So much bat! Learn about these weirdos! Featuring a promo for the audio drama Oz-9! Check them out on twitter @Oz9podcast Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.journals.uchicago.edu/doi/abs/10.1086/physzool.62.3.30157928 https://www.jstor.org/stable/pdf/2426339.pdf?refreqid=excelsior%3A10044196dd70551dfbf8eadb6331a6c5 https://www.hindawi.com/journals/isrn/2013/187415/ https://onlinelibrary.wiley.com/doi/full/10.1111/j.1469-7580.2007.00817.x https://link.springer.com/article/10.1007/s003600050049 https://www.sciencedirect.com/science/article/pii/000689938490132X https://www.frontiersin.org/articles/10.3389/fphys.2013.00117/full https://www.sciencedirect.com/science/article/abs/pii/S0960982219302672 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001676 https://link.springer.com/article/10.1007/s00359-019-01353-1 https://royalsocietypublishing.org/doi/full/10.1098/rsos.172024 https://www.wildlifeonline.me.uk/animals/article/bats-behaviour-social-structure https://www.scientificamerican.com/article/blood-sisters-what-vampire-bats-can-teach-us-about-friendship/ https://www.nature.com/articles/s41559-018-0476-8
46:26
May 1, 2020
Ep. 40 Cellulite and Skincare
Hey! New episode! Part 3 of our series on skin, we welcome back Scientist Matilde Miranda to discuss cellulite and skincare -- a topic she is very passionate about! Learn about all her fancy skincare tips, and don't forget you can tweet us (@dishpodcast) or her (@mirandamspock) to ask questions! Featuring a promo for podcast Grief Burrito -- check them out https://linktr.ee/Griefburrito and on twitter @GriefBurrito! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://onlinelibrary.wiley.com/doi/full/10.1046/j.1468-3083.2000.00016.x https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-2494.2006.00318.x https://link.springer.com/article/10.1007/s40257-015-0129-5 https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.12154 https://immunology.sciencemag.org/content/5/43/eaax5430 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926335/
1:00:31
April 27, 2020
Ep. 39 Bats Part 1: Awesome AND Diseased
Bats are awesome and do so many useful things for the environment -- BUT that is all for part 2! Part 1 is about bats as disease reservoirs -- something they seem to do very well. We talk about what diseases bats are typically reservoirs for and what particular bat immune system characteristics might enable them to be so good at harboring viruses. This episode has some COVID-19 talk, so if you're burned out on that either skip the first 12 min or skip the whole episode! Also! Bats are truly awesome. Please don't listen to this episode and come away from it with the thought of "we should get rid of bats". They aren't just important, they're wonderful! Also, a (very) recent study suggests bats don't have any more viruses (that infect humans) per species than other orders of mammals or birds. Lots of nuance in that study, but the main point is, be kind to bats!! Featuring a promo for CastJunkie! (@castjunkie on twitter, castjunkie.com) References: https://www.scientificamerican.com/article/how-chinas-bat-woman-hunted-down-viruses-from-sars-to-the-new-coronavirus1/ https://science.sciencemag.org/content/310/5748/676 https://academic.oup.com/ve/article/3/1/vex012/3866407#88156901 https://www.nature.com/articles/s41579-018-0118-9 https://jvi.asm.org/content/93/24/e01448-19.long https://www.nature.com/articles/s41586-018-0010-9 https://link.springer.com/article/10.1007/s12250-016-3713-9 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2546865/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197594/ https://www.nature.com/articles/s41564-018-0328-y https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945033/ https://www.mdpi.com/1999-4915/6/4/1759/htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822707/ https://www.mdpi.com/1999-4915/11/2/192/htm https://www.frontiersin.org/articles/10.3389/fimmu.2020.00026/full https://www.ingentaconnect.com/content/miiz/actac/2017/00000019/00000002/art00001 https://www.nature.com/articles/s41598-017-07824-2 https://www.nature.com/articles/ncomms14446 https://www.frontiersin.org/articles/10.3389/fimmu.2020.00026/full
35:38
April 23, 2020
Ep. 38 Immune System Part 2: Adaptive
Hey! New episode (and coronavirus free!) on the adaptive immune system! These are the cells that pump out antibodies, coordinate immune responses, and have memory so you can fight off diseases faster the second time around. Also featured is a note on immune system complexity, complex networks, and emergent properties! Trigger warning -- we mention the word 'suicide' in the context of cells telling other cells to undergo programmed cell death! If that doesn't sound like your cup of tea, please check out some of our other episodes! Stay safe out there everyone! Featuring a promo for @ContrivancePod (Previously known as Snark Tank Pod). Check them out on twitter or at contrivancepod.com. Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. References: https://www.frontiersin.org/articles/10.3389/fimmu.2018.01784/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954419/ http://jem.rupress.org/content/201/4/497.full https://www.ncbi.nlm.nih.gov/books/NBK27162/ https://www.nature.com/articles/nri3802 https://www.sciencedirect.com/science/article/pii/S1931312817300653 https://www.nature.com/articles/s41467-019-13636-x https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692051/ https://www.nature.com/articles/s41592-018-0305-7
47:56
April 20, 2020
Ep. 37.5 Bonus Minisode: COVID-19 Part 5
Hi everyone, this is a SARS-CoV-2/COVID-19 update episode on a treatment's (remdesivir) early experimental results, why antibody tests might not be the magic bullet everyone wants them to be, and one final discussion on the conspiracy that SARS-CoV-2 might be a bio-engineered virus. If you don't want any COVID-19 stuff going into your ear holes, avoid this episode! Listen to some of our other stuff, like our episodes on dogs, or skin, or acupuncture! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. If you're a creator of cool art stuff, check out the Boston Collective Film Festival at https://filmfreeway.com/boston and use promo code petridish References: https://coronavirus.jhu.edu/map.html https://outbreak.info/ https://covidtracking.com/data https://www.medrxiv.org/content/10.1101/2020.04.08.20057794v1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118619/ https://www.nejm.org/doi/full/10.1056/NEJMoa2007016 https://www.biorxiv.org/content/10.1101/2020.02.01.930537v2.full.pdf https://www.biorxiv.org/content/10.1101/2020.03.24.005561v1.full.pdf https://www.nature.com/articles/s41591-020-0820-9
44:32
April 16, 2020
Ep. 37 Acne and Wrinkles
Hey! It is part 2 of our 4 part series on skin, this time on acne and wrinkles! In our first episode we had Matilde Miranda, skin researcher extraordinaire (@mirandamspock on twitter) tell us about Skin Biology. Well she is back! And she is telling us the secrets of what acne is (not always bacterial!) and where wrinkles come from! Skincare enthusiasts should check this one out! Email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. If you're a creator of cool art stuff, check out the Boston Collective Film Festival at https://filmfreeway.com/boston and use promo code petridish References: https://labmuffin.com/fact-check-how-to-use-comedogenicity-ratings/ https://www.sciencedirect.com/science/article/pii/B9781845692711500017 https://www.hindawi.com/journals/mi/2017/2740963/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930074/ https://www.ncbi.nlm.nih.gov/pubmed/18489289 https://onlinelibrary.wiley.com/doi/full/10.1111/j.1468-2494.2011.00657.x https://www.ncbi.nlm.nih.gov/pubmed/26362110 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707681/ http://www.jmnn.org/article.asp?issn=2278-1870;year=2015;volume=4;issue=1;spage=47;epage=53;aulast=Borumand https://www.aafp.org/afp/2014/0801/p168.html https://www.nature.com/articles/s41598-018-33119-1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580982/
1:00:08
April 13, 2020
Ep. 36 Immune System Part 1: Innate
Hi everyone! Hope you are keeping it safe out there! This week we give you part 1 of 2 on the immune system. We'll be beginning with innate immunity this time and will be talking about the adaptive immune system in the next episode! What cells are on the front line, fighting on the front line to defend your body? Osmosis Jones! Check out our patreon at patreon.com/petridish email us at petridishpod -at- gmail.com. On twitter @dishpodcast and instagram @petridishpodcast. If you're a creator of cool art stuff, check out the Boston Collective Film Festival at https://filmfreeway.com/boston and use promo code petridish References: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701915/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903395/ https://www.ncbi.nlm.nih.gov/pubmed/20664169/ https://www.immunology.org/public-information/bitesized-immunology/cells/eosinophils https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571705/ https://science.sciencemag.org/content/348/6237/aaa6566 https://www.ncbi.nlm.nih.gov/pubmed/18425107 https://www.sciencedirect.com/science/article/pii/S0092867418309115?via%3Dihub https://www.frontiersin.org/articles/10.3389/fimmu.2015.00257/full https://onlinelibrary.wiley.com/doi/full/10.1002/9780470015902.a0001213.pub3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526850/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384419/
51:58
April 6, 2020
Ep. 35 Skin Biology
Hey folks! How about a corona- and disease-break? This special mid-week release of Petri Dish is about SKIN! This episode is part of a (non-sequential) series on skin-related bio stuff, in which we had a guest skin scientist, Matilde Miranda, sit in and chat with us about a bunch of different skin things. This episode is the primer, it is going to help you get nice and situated for the rest of the series, which will cover: acne, wrinkles, cellulite, skincare tips, aging, and the relationship between skin and sun. So much! This episode is about the layers of skin, of which there are a ton. Featuring a promo for Not Suitable for Adults Podcast, check them out at  https://linktr.ee/not4adultscast and on twitter @Not4AdultsCast Contact us @dishpodcast on twitter, @petridishpodcast on instagram, and petridishpod -at- gmail.com! Hit us up if you have any skincare questions for Matilde (@mirandamspock)! Reference: Matilde's Brain https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175800/
58:37
April 1, 2020
Ep. 34 Epidemic: Viral Hemorrhagic Fevers
Hey! This is another in our series on pandemics... except there hasn't really been a pandemic of viral hemorrhagic fevers, just epidemics! But that doesn't make them less freaky-deaky, just think about how you feel about EBOLA. Ebola isn't the only virus in town though, so tune in to hear about all the different viruses that cause this class of illness. Content-warning! We discuss, at the end of this episode, a little comparison between ebolavirus and SARS-CoV-2. If you aren't into that, we actually give a warning in the episode too, so feel free to tune out then! Featuring a promo for Round & Round The Podcast, check them out at https://www.rnrthepodcast.com/ and @RnRThePodcast on twitter! References: https://www.cdc.gov/vhf/virus-families/arenaviridae.html https://www.cdc.gov/hantavirus/hfrs/index.html https://www.cdc.gov/vhf/crimean-congo/transmission/index.html https://www.cdc.gov/vhf/rvf/transmission/index.html https://www.nejm.org/doi/full/10.1056/NEJMoa1805435 https://www.statnews.com/2019/07/17/debate-testing-second-ebola-vaccine/ https://www.tandfonline.com/doi/full/10.1080/14760584.2019.1698952 https://www.msf.org/drc-ebola-outbreak-crisis-update https://www.nature.com/articles/s41591-019-0602-4 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885103/ https://www.ncbi.nlm.nih.gov/books/NBK143281/ https://www.ncbi.nlm.nih.gov/books/NBK531468/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885103/ https://www.cdc.gov/measles/transmission.html
59:24
March 30, 2020
Ep. 33.5 Bonus Minisode: CoronaTreatments
For the 16 people out there that aren't sick of COVID-19/SARS-CoV-2 information already, here is another BONUS MINISODE on just that topic! This time around we're covering treatments that scientists and doctors around the world are trying to use to fight COVID-19. We discuss the WHO's new clinical trial to gather some data on these treatments, talk about 5 of the treatments more specifically, and then go into debunking mode! Useful links on the latest number of infected: https://covidtracking.com/us-daily/ https://coronavirus.jhu.edu/map.html References: https://www.sciencemag.org/news/2020/03/who-launches-global-megatrial-four-most-promising-coronavirus-treatments https://www.nytimes.com/2020/03/23/health/coronavirus-drugs-remdesivir.html https://www.reuters.com/article/us-health-coronavirus-gilead-sciences/gileads-potential-coronavirus-treatment-gets-fdas-orphan-drug-label-idUSKBN21A3PR https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056.full.pdf https://www.nature.com/articles/s41584-020-0372-x https://www.sciencedirect.com/science/article/pii/S0166354220301145?via%3Dihub http://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA.pdf https://www.jstage.jst.go.jp/article/bst/14/1/14_2020.01047/_pdf/-char/en http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2020.03.03 https://www.ncbi.nlm.nih.gov/pubmed/12662125 https://www.nejm.org/doi/10.1056/NEJMoa2001282 https://www.fda.gov/vaccines-blood-biologics/investigational-new-drug-ind-or-device-exemption-ide-process-cber/investigational-covid-19-convalescent-plasma-emergency-inds https://www.jci.org/articles/view/138003 https://www.latimes.com/science/story/2020-03-20/how-blood-from-people-who-survived-covid-19 https://www.thelancet.com/action/showPdf?pii=S2213-2600%2820%2930116-8
33:31
March 25, 2020
Ep. 33 Pandemic: PLAGUE
The second episode in our pandemic series is about one of the OGs, plague! This sucker has killed hundreds of millions of people in the past couple millennia, but has been brought low by antibiotics (yay SCIENCE!). But is it gone forever? Nah. Also, bubonic plague as a bioweapon?! It isn't a new idea... Promo this week is for Controller Disconnected Podcast! Check them out at  https://www.condisconnected.com/  and on twitter @condisconnected We are also on twitter @dishpodcast and on instagram @petridishpodcast AND have an email address petridishpod@gmail.com. Hit us up! References: https://www.nationalgeographic.com/news/2014/1/140129-justinian-plague-black-death-bacteria-bubonic-pandemic/ https://www.cdc.gov/plague/maps/index.html https://www.sciencedirect.com/science/article/abs/pii/S1286457999002051 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200711/ http://www.centerforhealthsecurity.org/our-work/publications/plague-fact-sheet https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)60858-2/fulltext https://www.usgs.gov/centers/nwhc/science/sylvatic-plague?qt-science_center_objects=0#qt-science_center_objects https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256048/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200711/ https://emergency.cdc.gov/agent/agentlist-category.asp http://www.bordeninstitute.army.mil/cwbw/default_index.htm https://www.sciencedirect.com/science/article/pii/S2590053619300230
59:06
March 23, 2020
Ep. 32 Pandemic: Tuberculosis
This new series of episodes we're doing is on different pandemic diseases throughout history, with our first disease being tuberculosis! The series won't be a bunch of episodes in a row, but as we do more and more diseases we will begin comparing different pandemics. This episode covers the modern tuberculosis situation (2 billion people infected!) and our long history with the disease. We'll talk about treatments, drug resistance, disease characteristics, and the vaccine. Featuring a promo for the great podcast Just the Zoo of Us, check them out! https://www.justthezooofus.com/ @JusttheZooofUs on twitter Become a patron at patreon.com/petridish! References: https://www.who.int/tb/publications/factsheet_global.pdf https://www.bcm.edu/departments/molecular-virology-and-microbiology/emerging-infections-and-biodefense/introduction-to-infectious-diseases https://www.atsjournals.org/doi/full/10.1164/rccm.200402-140OE https://www.cdc.gov/nchs/fastats/deaths.htm https://www.nature.com/articles/nrmicro.2018.8 https://www.smithsonianmag.com/science-nature/how-tuberculosis-shaped-victorian-fashion-180959029/ https://www.cdc.gov/tb/publications/factsheets/general/mbovis.htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946903/ https://www.aafp.org/afp/2005/1101/p1761.html https://www.sciencedirect.com/science/article/pii/S0022534707022884 https://www.who.int/vaccine_safety/initiative/tools/BCG_Vaccine_rates_information_sheet.pdf https://link.springer.com/chapter/10.1007/978-1-4939-6667-7_20 https://www.sciencedirect.com/science/article/pii/S0264410X14007099 https://www.ijidonline.com/article/S1201-9712(19)30100-6/pdf https://www.nature.com/articles/nrurol.2014.15 https://www.canjurol.com/html/free-articles/V15I02-2-Legends_DrMorales.pdf https://www.sciencedirect.com/science/article/pii/S1078143900000995?via%3Dihub
48:58
March 16, 2020
Ep. 31 Dogs! Pupperinos Part 2
This is the second half of our two-parter on mankind's best friend! Last week's episode covered domestication and breeds. This week is about dog behavior, dog jobs, and dog fritos feet. Featuring a promo for the podcast Snark Tank -- check them out on twitter @SnarkTankPod and at http://SnarkTankPod.com References: https://www.sciencedirect.com/science/article/pii/S0376635714000473 https://www.tandfonline.com/doi/full/10.1080/14616734.2018.1517812 https://www.nature.com/articles/s41598-017-12781-x https://www.pnas.org/content/116/29/14677?fbclid=IwAR3lu8dKSqFFvcuWQIK5KEzgiwQvH-ZfzvV4aIsCE_yIUSMqya5BiNFxxj0 https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.577.3 https://www.sciencedirect.com/science/article/pii/S2405844020301560?via%3Dihub https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839826/ https://www.thesprucepets.com/dog-paws-smell-like-corn-chips-3385624 https://pdfs.semanticscholar.org/ae70/f4c8e88b76e6ac12de2c10b66ee8fb935cdc.pdf https://www.sciencedirect.com/science/article/abs/pii/S0039914018303552 https://www.sciencedirect.com/science/article/abs/pii/S0376635717300104 https://bmcurol.biomedcentral.com/articles/10.1186/1471-2490-14-22 https://iopscience.iop.org/article/10.1088/1752-7163/ab716e/meta https://www.sciencedirect.com/science/article/abs/pii/S1558787817300539 https://link.springer.com/article/10.1007/s10071-018-01234-1/tables/1?shared-article-renderer https://www.jneurosci.org/content/jneuro/39/39/7748.full.pdf https://royalsocietypublishing.org/doi/full/10.1098/rspb.2019.0716 https://www.frontiersin.org/articles/10.3389/fpsyg.2017.01520/full#h5 There are actually ~10 more references
1:03:50
March 10, 2020
Ep. 30.5 Bonus Minisode: Corona-USA
SARS-CoV-2, HCOV-19, nCoV-19... Whatever you want to call this coronavirus, it is making a splash in countries all over the globe: big outbreaks in Italy, South Korea, and Iran, along with growing numbers of infected people (largely untested) in the USA. In this episode, Sean and Nathan discuss the US CDC's response to the coronavirus and dive a little into a paper about there being two potential 'strains' of this virus already. References: https://www.medrxiv.org/content/10.1101/2020.02.25.20027953v2 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30419-0/fulltext https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30462-1/fulltext https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30557-2/fulltext https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30551-1/fulltext https://www.nejm.org/doi/full/10.1056/NEJMoa2002032 https://www.theatlantic.com/health/archive/2020/03/how-many-americans-have-been-tested-coronavirus/607597/
21:36
March 10, 2020
Ep. 30 Dogs! (Because We Did One On Cats) Part 1
Humankind's best friend! Pupperinos! In this week's episode of Petri Dish Nathan and Sean talk about dogs! This is part 1, where we talk about the domestication of dogs and some biological information about dog breeds! In part 2 we'll go into of the science of dog behavior and biology.  Featuring a promo for the podcast Controller Disconnected! Follow them @condisconnected on Twitter! Follow us too @dishpodcast and email us petridishpod -at- gmail.com. If you like what we do, consider giving us a buck a month at patreon.com/petridish References: https://www.sciencedirect.com/science/article/pii/027841659190021O https://royalsocietypublishing.org/doi/full/10.1098/rsos.160107 https://www.nature.com/articles/s41598-019-40468-y https://www.frontiersin.org/articles/10.3389/fpsyg.2014.01582/full https://www.tandfonline.com/doi/full/10.1080/08912963.2016.1262854 https://onlinelibrary.wiley.com/doi/full/10.1111/ede.12319 https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0535-2 https://www.sciencedirect.com/science/article/pii/S0169534719303027 https://www.biorxiv.org/content/10.1101/660829v2.full https://royalsocietypublishing.org/doi/full/10.1098/rspb.2019.1929 https://www.mdpi.com/2073-4425/10/10/757/htm https://www.sciencedirect.com/science/article/pii/S0305440316301789 https://academic.oup.com/mbe/article/30/5/1103/997804 https://science.sciencemag.org/content/352/6290/1228 https://www.mdpi.com/2073-4425/10/10/757/htm https://link.springer.com/chapter/10.1007%2F13836_2018_27 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384140/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705110/ https://academic.oup.com/dnaresearch/article/19/3/275/475438
51:26
March 2, 2020
Ep. 29 Vaccines! Part 2
Hi Folks! If you're just stopping by, consider listening to Vaccines Part 1 to get info on the types of vaccines and what ingredients go into making them -- we use some of those terms here! In this ep we talk about how vaccines work on a cell level, how long and how well different vaccines work, and wrap it up with next-generation vaccines! Featuring a promo for Dad and Daughter Movies Podcast -- follow them on twitter @DDMovies2! If you like what we do, consider tossing $1 a month our way at patreon.com/petridish. Follow us on twitter @dishpodcast! Email us at petridishpod -at- gmail.com References:  https://www.npr.org/sections/goatsandsoda/2019/12/05/785177595/measles-numbers-were-bad-in-2018-this-year-theyre-even-worse https://www.sciencemag.org/news/2019/04/how-long-do-vaccines-last-surprising-answers-may-help-protect-people-longer https://www.who.int/biologicals/areas/vaccines/bcg/en/ https://www.nature.com/articles/s41586-019-1817-8 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274812/ https://stm.sciencemag.org/content/11/522/eaax7888.abstract
43:30
February 24, 2020
Ep. 28.5 Bonus Minisode: Still Coronavirus!
Hey! The novel coronavirus (now SARS-CoV-2, which causes COVID-19) is still out and about, doing naughty stuff! But what do we know about this sucker now, a couple of months in to this not-quite-pandemic-yet? What are the latest stats on the number of cases, what countries should we be looking at, what do we know now about the biology of COVID-19, and also conspiracy theories are dumb. Get some info on this latest outbreak here on Petri Dish! If you like what we're doing here at Petri Dish, consider chipping in $1 a month at our patreon: patreon.com/petridish Questions or concerns? Email us at petridishpod -at- gmail.com or tweet at us @dishpodcast! References: https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1 https://www.biorxiv.org/content/10.1101/2020.02.04.933135v1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457962/ https://www.nejm.org/doi/full/10.1056/NEJMoa2001191?query=recirc_mostViewed_railB_article https://www.nejm.org/doi/full/10.1056/NEJMoa2001316?query=recirc_mostViewed_railB_article https://www.biorxiv.org/content/10.1101/2020.01.23.916395v2 https://www.sciencemag.org/news/2020/02/paper-non-symptomatic-patient-transmitting-coronavirus-wrong https://www.sciencedirect.com/science/article/pii/S0140673620302609 https://www.sciencedirect.com/science/article/abs/pii/S1567134820300447 https://www.sciencemag.org/news/2020/01/mining-coronavirus-genomes-clues-outbreak-s-origins https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30251-8/fulltext https://www.nature.com/articles/s41586-020-2012-7_reference.pdf https://www.biorxiv.org/content/10.1101/2020.02.04.933135v1 https://www.biorxiv.org/content/10.1101/2020.02.19.950253v1 https://www.thelancet.com/pb-assets/Lancet/pdfs/S2213260020300795.pdf https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30411-6/fulltext
18:28
February 24, 2020
Ep. 28 Vaccines! Part 1
If you're a listener to this podcast, it is probably safe to assume that you have heard of vaccines and likely are pro-vaccine. But there is a lot of cool science going on under the hood of vaccines! This week on Petri Dish Sean, Nathan, and guest Andrei dig in to the stuff that make up vaccines, the different kinds of vaccines, and whether vaccines are dangerous or not (they aren't, really). This is part 1! In part 2 we talk about how they work on a cell biology level and what next-gen vaccines might look like. Featuring a promo for Round & Round The Podcast -- two old Navy buddies shoot the shit on all kinds of topics -- check them out! https://www.rnrthepodcast.com/ Follow us on twitter @dishpodcast! Email us: petridishpod -at- gmail.com! Check out our patreon page and sign up for as little as $1 a month to help fund us say all these words n stuff www.patreon.com/petridish! References: https://www.sciencedirect.com/science/article/pii/S0264410X07002770 https://link.springer.com/chapter/10.1007/978-1-4419-1339-5_2 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151719/ https://www.jstor.org/stable/218112?seq=14 https://www.vaccines.gov/basics/types
39:40
February 17, 2020
Ep. 27 Intermittent Fasting: How, What, and Why?
Heya folks, today's episode is about intermittent fasting, a new(ish) and increasingly popular way of trying to lose weight. Is it just a fad diet, or something more complicated? How does someone go about doing intermittent fasting and what does it do on a biological level (as far as we know)?As a note: Intermittent fasting involves changing how and when you eat, and therefore is a topic that can be sensitive for those who have eating disorders. If you are concerned about the topic, please feel free to skip the episode and/or contact help, like the free helpline of the National Eating Disorders Association: https://www.nationaleatingdisorders.org/help-support/contact-helpline.Also! Because this topic involves a diet that can impact your health, we want to again mention that this does not constitute medical advice and you should discuss the topic with your doctor first.This week's promo is for the Not Suitable for Adults podcast! Check them out on twitter: @Not4AdultsCast http://not4adultscast.podbean.com/References:https://www.nejm.org/doi/full/10.1056/NEJMra1905136https://www.mdpi.com/2072-6643/11/10/2442/htm https://www.annualreviews.org/doi/full/10.1146/annurev-nutr-071816-064634https://www.annualreviews.org/doi/full/10.1146/annurev-nutr-071816-064916https://www.ncbi.nlm.nih.gov/pubmed/18641044 https://www.ncbi.nlm.nih.gov/pubmed/16647374https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058473/https://www.annualreviews.org/doi/full/10.1146/annurev-pharmtox-010814-12434https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(18)30001-8https://link.springer.com/article/10.1007/s13105-018-0658-5https://www.sciencedirect.com/science/article/pii/S1550413117305041https://www.sciencedirect.com/science/article/pii/S089158490600801X?via%3Dihubhttps://www.sciencedirect.com/science/article/pii/S2211124716305769https://www.sciencedirect.com/science/article/abs/pii/S2211034818301421https://www.tandfonline.com/doi/abs/10.1080/030097401750065256https://www.nature.com/articles/cddis201414https://www.cell.com/fulltext/S0092-8674(11)01276-1https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106288/https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.1444https://www.nature.com/articles/s41467-019-09897-1https://www.frontiersin.org/articles/10.3389/fimmu.2019.01402/fullhttps://pubs.acs.org/doi/abs/10.1021/acs.jproteome.9b00090https://academic.oup.com/ajcn/article/102/2/464/4564588https://www.sciencedirect.com/science/article/pii/S0960982218304433
55:56
February 10, 2020
Ep. 26 CATS! (Not the Musical)
This topic was requested by co-host Nathan, who had read several news articles recently suggesting that cats are menaces, plagues upon the world and humankind. IS THIS TRUE?! In this episode, we begin with a brief history on the semi-domestication of cats, and then move into some of their cool and unique biology. Then we discuss cats as invasive species and cats as vectors for Toxoplasma gondii, a crazy parasite! Learn about catnip alternatives and landing on your feet, this week on Petri Dish! Hit us up on twitter: @dishpodcast or via email: petridishpod -at- gmail.com! References:https://www.nature.com/articles/s41559-017-0139https://journals.plos.org/plosone/article%3Fid%3D10.1371/journal.pone.0147295https://journals.sagepub.com/doi/full/10.1177/1098612X18771203https://onlinelibrary.wiley.com/doi/full/10.1111/age.12008https://www.sciencemag.org/news/2019/05/cats-rival-dogs-many-tests-social-smarts-anyone-brave-enough-study-themhttps://www.scientificamerican.com/article/the-inner-life-of-cats/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356310/https://journals.sagepub.com/doi/full/10.1016/j.jfms.2003.07.001https://iopscience.iop.org/article/10.1088/1361-6404/aaac06/metahttps://www.pnas.org/content/111/48/17230.fullhttps://abcbirds.org/threat/cats-and-other-invasives/https://www.wired.com/story/cats-australia-bushfires/ https://www.nytimes.com/2019/04/25/magazine/australia-cat-killing.htmlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/https://link.springer.com/chapter/10.1007/978-3-319-67664-7_6https://www.ncbi.nlm.nih.gov/pubmed/14567210https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1690701/pdf/11007336.pdf https://academic.oup.com/icb/article/54/2/118/2797844https://www.mdpi.com/2076-0817/6/2/19/htm#B2-pathogens-06-00019https://www.mayoclinic.org/diseases-conditions/toxoplasmosis/symptoms-causes/syc-20356249https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-019-0503-3 https://www.cambridge.org/core/journals/parasitology/article/toxoplasmosis-in-humans-and-animals-in-brazil-high-prevalence-high-burden-of-disease-and-epidemiology/CD91DD8A60F76A2E4D02752FD6D49802 https://www.sciencedirect.com/science/article/pii/S0020751909001842?via%3Dihubhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519211/https://www.sciencedirect.com/science/article/pii/S1567134818303976https://link.springer.com/article/10.1007/s11011-016-9822-1https://www.mdpi.com/2076-0817/6/1/3/htmhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757034/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6564815/
1:07:22
February 3, 2020
Ep. 25 Aging and Immortality Part 2
Hey everyone, I hope you checked out our bonus minisode on the new coronavirus! Here is our regularly scheduled full episode, the part 2 on Aging and Immortality! This time we turn our focus to humans, and what the current science says about how to live longer and healthier! Can being hungry all the time make you immortal? Does NAD+ supplements or metformin do anything? Find out!If you like what we do, consider supporting us at www.patreon.com/petridish , even a few dollars a month would help us keep making all the stuff! You can contact us directly via email at petridishpod -at- gmail.com and via twitter @dishpodcast!References:https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0547-yhttps://onlinelibrary.wiley.com/doi/full/10.1111/acel.12283https://www.sciencedirect.com/science/article/pii/S1550413115002247https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12708 http://www.bioscirep.org/content/39/5/BSR20190537.abstracthttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736576/https://www.nature.com/articles/s41591-018-0273-6https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13028?fbclid=IwAR1mNGFIaTnYfkjK7eNJc-UvV0XpzmROVyHCJLRg4MgxwQNXOJ0XcR-8yTUhttps://www.nature.com/articles/s41586-019-1365-2https://www.jstage.jst.go.jp/article/endocrj/advpub/0/advpub_EJ19-0313/_article
54:11
January 27, 2020
Ep. 24.5 Bonus Minisode: Coronavirus!
Hi Everyone, Happy Year of the Rat! This is a special mini-episode we are releasing on the novel coronavirus currently infecting people in China (and now elsewhere). This short episode covers what a coronavirus is in general, and what we know about this new one. It also has a little conspiracy theory stuff at the end, but that's just for light hearted purposes, because all in all new diseases can be dour business. Listen in to learn some stuff, and realistically, don't panic! Referenceshttps://www.nature.com/articles/d41586-020-00154-whttps://www.thelancet.com/pb-assets/Lancet/pdfs/S0140673620301549.pdfhttps://www.medrxiv.org/content/10.1101/2020.01.23.20018549v1https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700180/https://www.nature.com/news/inside-the-chinese-lab-poised-to-study-world-s-most-dangerous-pathogens-1.21487https://www.businessinsider.com/china-information-crackdown-on-wuhan-coronavirus-2020-1
19:07
January 27, 2020
Ep. 24 Aging and Immortality Part 1
For folks in the USA, happy Martin Luther King Jr. Day! This week on Petri Dish Nathan and Sean discuss the biology of aging. What does it actually mean to age, when some animals out there are biologically immortal and get to just hang out forever until they get eaten? What happens on a cellular level when we age? What can we learn from other species about the aging process? This is the first part of a two-part series -- next week we'll discuss human aging in the context of what we can try to do to slow or halt it!References:https://www.pnas.org/content/early/2020/01/07/1916548117https://www.sciencedirect.com/science/article/pii/S0092867413006454https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247388/https://www.sciencedirect.com/science/article/pii/S2211124714010195https://www.pnas.org/content/early/2019/09/12/1904611116https://en.wikipedia.org/wiki/Nothobranchius_furzerihttps://onlinelibrary.wiley.com/doi/full/10.1111/j.1474-9726.2012.00847.xhttps://link.springer.com/article/10.1007/s11357-013-9597-9https://www.nature.com/articles/ncomms14063https://royalsocietypublishing.org/doi/full/10.1098/rsbl.2010.0539https://onlinelibrary.wiley.com/doi/full/10.1002/bies.201000132https://www.sciencedirect.com/science/article/pii/S1568163714000622https://en.wikipedia.org/wiki/Turritopsis_dohrniihttps://oaktrust.library.tamu.edu/handle/1969.1/173118https://www.sciencedirect.com/science/article/pii/S1055790316303359https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326690/https://www.sciencedirect.com/science/article/pii/S0047637417300015https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0547-yhttps://www.pnas.org/content/115/8/1801.shorthttps://www.hindawi.com/journals/omcl/2019/4502819/abs/https://www.sciencedirect.com/science/article/pii/B978012411596500006Xhttps://www.sciencedirect.com/science/article/pii/S0092867416309813
49:38
January 20, 2020
Ep. 23 Booze and Hangover Science
Welcome to the first Petri Dish episode recorded in 2020! This one is about the science behind the effects of booze (ethanol), and our current best understanding of what hangovers are and what you can do about them! Would this episode have been more apropos if released closer to New Year's Day? Maybe, but we were all too hung over, so whatever. Tune in for a brief history of alcohol, a discussion of what ethanol does to you, and whether that stuff about a glass of wine a day being good for you is real or not. Do hangover cure IV bangs work? Did you even know that was a thing? What about prairie oysters? Doesn't that sound more like a euphemism for poop than a hangover cure? Tune in!References:https://link.springer.com/chapter/10.1007/164_2017_80https://www.nature.com/articles/s41698-017-0038-6https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164842/https://pubs.rsc.org/en/content/articlehtml/2016/mb/c5mb00740bhttps://www.sciencedirect.com/science/article/pii/S0890623813000774https://academic.oup.com/alcalc/article/54/3/196/5420612https://www.ingentaconnect.com/content/ben/cdar/2016/00000009/00000002/art00005 https://academic.oup.com/alcalc/article/43/2/124/122754https://www.ncbi.nlm.nih.gov/pubmed/4460229https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2362.1976.tb00498.xhttps://www.sciencedirect.com/science/article/pii/S0306452214002851https://link.springer.com/article/10.1007/s41782-017-0008-7https://www.ncbi.nlm.nih.gov/pubmed/2275637https://pdfs.semanticscholar.org/28aa/8f3c4fdceedb3a6eec5b80e744b71465167a.pdfhttps://onlinelibrary.wiley.com/doi/full/10.1002/hup.2600https://pubs.rsc.org/en/content/articlehtml/2014/fo/c3fo60481khttps://www.hindawi.com/journals/apm/2012/617942/https://www.sciencedirect.com/science/article/pii/S0741832919300825
1:00:24
January 13, 2020
Ep. 22 What is Epigenetics?
In this week's episode, Sean and Nathan are joined by guest Liliana Escobedo to discuss epigenetics, which is either all of the stuff besides your genes that affects the functions of your cells OR non-genetic stuff that happens in your life that can affect your kids and grandkids, depending on what scientists you ask for a definition! Can eating too much food during your lifetime affect your grandkids through your sperm or eggs getting tweaked? Find out this week on Petri Dish!Featuring a promo for the very fun podcast "The Ladies of Strange":"The Ladies of Strange is a comedy podcast where we talk about everything from true crime, paranormal, conspiracy, and anything else we find questionable, odd, or eerie. Sit down with us every Thursday for a story presented by one of the hosts and learn with us that everyone has something they find strange, let us tell you why (sometimes) it’s not." https://theladiesofstrange.com/Questions or issues? Hit us up @dishpodcast on twitter or email us petridishpod-at-gmail.comReferences:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391566/https://academic.oup.com/hmg/article/22/23/4726/1162012https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845587/https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.12136https://www.nature.com/articles/nn.3695https://www.nature.com/articles/nrg.2016.106http://perspectivesinmedicine.cshlp.org/content/6/5/a022988https://www.nature.com/articles/s41556-018-0242-9https://www.nature.com/articles/s41467-018-05445-5https://www.sciencedirect.com/science/article/pii/B978012816363400002Xhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020004/https://www.annualreviews.org/doi/full/10.1146/annurev-genet-120417-031404https://ghr.nlm.nih.gov/condition/prader-willi-syndrome#geneshttps://www.sciencedirect.com/science/article/pii/S0002929707605734https://www.nature.com/articles/nn.3695https://www.nature.com/articles/nm.2893https://www.pnas.org/content/111/5/1873.fullhttps://www.sciencedirect.com/science/article/pii/S1550413116300067https://www.nature.com/articles/s41556-018-0242-9https://www.sciencedirect.com/science/article/pii/S1084952115001305?via%3Dihubhttps://www.sciencedirect.com/science/article/pii/B978012816363400002Xhttps://www.sciencedirect.com/science/article/pii/B9780128132098000091https://jme.bioscientifica.com/view/journals/jme/60/2/JME-17-0189.xmlhttps://science.sciencemag.org/content/354/6308/59https://www.sciencedirect.com/science/article/pii/S2212877818301042http://perspectivesinmedicine.cshlp.org/content/6/5/a022988.full
59:47
January 6, 2020
Ep. 21 Human Sex and Evo Psych
Hey everyone, this week is part 2 of our episodes on sex, this time focusing on sex determination in humans and Sean's rocky relationship with the field of evolutionary psychology! Nathan and Sean discuss the XY chromosome system, the SRY gene, all sorts of things that can make people fall outside of the XX-XY female-male dichotomy, and more!This episode our very real promo is for a non-fiction horror podcast Pomegranates and Pitchforks! They cover true crime, mythology -- anything that has to do with horror -- check them out! https://pompitchpod.podbean.com/References:https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161045https://www.karger.com/Article/FullText/479946https://www.nature.com/articles/s41586-019-1765-3https://www.pnas.org/content/100/16/9103https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111733https://science.sciencemag.org/content/322/5906/1331https://www.sciencedaily.com/releases/2011/05/110524070310.htmhttps://www.iflscience.com/plants-and-animals/scientists-discover-evolutionary-advantage-homosexual-sex/https://www.healthguidance.org/entry/17322/1/why-are-men-attracted-to-women-who-wear-makeup.htmlhttps://www.medicaldaily.com/baby-got-back-male-preference-curved-spines-may-explain-why-they-love-big-butts-324324https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001109https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699887/https://www.researchgate.net/publication/41415714_Evolutionary_Psychology_Controversies_Questions_Prospects_and_Limitationshttps://www.sciencedirect.com/science/article/pii/S136466130500104Xhttps://journals.sagepub.com/doi/full/10.1177/147470491201000406https://link.springer.com/article/10.1007%2Fs11199-010-9895-yhttps://journals.sagepub.com/doi/full/10.1177/147470491401200301https://www.sciencemag.org/news/2019/03/does-dark-triad-personality-traits-make-you-more-successful https://psyarxiv.com/mbkr8/
1:04:12
December 30, 2019
Ep. 20 Animal Sex! Part 1
This week on Petri Dish Sean and Nathan dive into the apparently controversial topic of biological sex. In this part 1 of a two part discussion, Sean and Nathan talk about the biological basis for the concepts of 'male' and 'female' in non-human organisms ranging from yeast to plants to reptiles. They bring up different kinds of chromosomal systems, weirdos like the platypus and clownfish, and whether climate change could turn more sea turtles into ladies!In this episode we feature a promo for another podcast, Just the Zoo of Us. If you like animal facts, check them out! https://www.justthezooofus.com/Please contact us if you have any questions or feelings about the episodes! You can reach us on twitter @dishpodcast or by email petridishpod -at- gmail.com. We also have a patreon in case you want to sponsor the work we are doing! patreon.com/petridish .References:https://www.sciencedirect.com/science/article/pii/S0016648015002737https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413164/#!po=0.735294https://ctswordtail.weebly.com/blog/sex-determination-in-platyfish-and-swordtailshttps://www.ncbi.nlm.nih.gov/pubmed/12900561https://www.ncbi.nlm.nih.gov/pubmed/21392300https://www.nature.com/articles/6801068https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1692900/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838700/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679206/https://hortnews.extension.iastate.edu/2009/2-4/monoecious.htmlhttps://link.springer.com/article/10.1007/s11160-009-9123-4https://www.sciencedirect.com/science/article/pii/S0044848602000571https://www.sciencedirect.com/science/article/pii/S1546509808601132https://www.nature.com/articles/nature14574https://royalsocietypublishing.org/doi/full/10.1098/rspb.2016.2576
40:08
December 23, 2019
Ep. 19 Cancer Part 2
Hey everyone, this week we complete our discussion about cancer. Last episode we talked about what cancer is, where it comes from, and what the different types are. This week, Sean and Nathan talk about the risk factors associated with cancer, the current treatment methodologies, and the next-generation of treatments that scientists are working on!Also featured in this episode is a promo commercial for another podcast called Songbirding, a chill podcast focused around listening to different birds singing -- if that sounds like your thing, then check it out!You can contact us on twitter @dishpodcast and by email at petridishpod -at- gmail.com. Let us know what you think about the episodes, things we missed, or things you'd like us to talk about!References:https://www.cancer.gov/about-cancer/treatment/research/car-t-cellshttps://embryo.asu.edu/pages/teratomashttps://www.pnas.org/content/72/9/3585.shorthttps://www.cancer.gov/about-cancer/understanding/disparities
46:36
December 16, 2019
Ep. 18 Cancer Part 1
Cancer is the leading cause of death worldwide and it is a biologically complex set of diseases, so Sean and Nathan dive in to the biology this week (and next week) on Petri Dish. Cancer affects almost everyone in the world, with millions of people diagnosed each year and almost everyone knowing someone who has had cancer. This episode, they talk about what cancer is, what the main theories are on the cause of cancer, and the different kinds of cancer out there. Next week we discuss current and next-gen treatments for cancer and risk-factors for cancer! Tune in!Have questions? Want to yell at Sean or Nathan? Well, Nathan doesn't read the twitter, but Sean does! Tweet at him @dishpodcast, or email them at petridishpod -at- gmail.com. Check us out at patreon.com/petridish!References:https://www.nature.com/articles/s41551-019-0420-5https://www.pnas.org/content/116/9/3502https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100937https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501415/https://www.nature.com/articles/s41551-019-0423-2https://www.nature.com/articles/d41586-019-02892-y
48:03
December 9, 2019
Ep. 17 Cannabinoids Part 2
Welcome back to Petri Dish! Hope Americans had a nice Thanksgiving break, and are refreshed and recharged for another episode. We're picking up where we left off last time with part 2 of Cannabinoids. We discussed the plant, compounds, and briefly covered what they can do to you last episode. But this episode, we dive deeper into the purported health benefits and hazards of THC and CBD. We talk about cancer, glaucoma, and more!If you have any feedback, positive or negative, let us know! You can tweet at us @dishpodcast or you can email us at petridishpod at gmail.com. You can also swing over to our patreon for early releases and other stuff! References:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791144/https://www.nejm.org/doi/full/10.1056/nejmra1407304https://link.springer.com/article/10.1007%2Fs00415-012-6634-zhttps://www.sciencedirect.com/science/article/pii/S0753332216321060https://www.nature.com/articles/npp201751https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616224/https://www.nature.com/articles/nutd20139https://www.tandfonline.com/doi/full/10.1080/08897077.2016.1219438https://www.nature.com/articles/nrcardio.2017.130https://onlinelibrary.wiley.com/doi/full/10.1002/wps.20341
49:02
December 2, 2019
Ep 16. Cannabinoids Part 1
Hello and happy almost Thanksgiving to folks in the USA! In honor of a holiday that features stuffing yourself, we're covering the muchies-inducing plant, Cannabis, and the chemicals it produces. With more and more locations around the world decriminalizing and legalizing marijuana, this is a great time to ask yourself "what the fuck does this shit actually do, like real science-wise"? This episode, the first half of a two-parter on cannabinoids, covers info about the plant itself, the chemical class of compounds that includes THC and CBD, your own internal endocannabinoid system, and a fast run-through on what the current science says about medical benefits of cannabinoids! And tune in next week for the second part, where we dive into the current science of whether cannabinoids help with fighting cancer, treating glaucoma, and fighting addiction to other substances. If you like (or don't like, or really have pretty much any feelings about) what you hear, let us know on twitter @dishpodcast and/or via email: petridishpod -at- gmail.com! Also, feel free to hit us up on patreon at www.patreon.com/petridish !References:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740396/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340993/https://books.google.com/books?hl=en&lr=&id=FTW9DgAAQBAJ&oi=fnd&pg=PR1&dq=cannabinoids&ots=-if-4V8guT&sig=UwmXmKmGlUs4DUl6q47FM0I-RzY#v=onepage&q=cannabinoids&f=falsehttps://link.springer.com/article/10.1007/s11920-017-0775-9https://www.nature.com/articles/npp2017162
36:35
November 25, 2019
The Wonders and Dangerous of Vaping
Hi Everyone! This week Sean and Nathan are joined by certified young person Griffin Allen, who has street-level knowledge about VAPING -- the recently-in-the-news drug delivery phenomenon that has seen an unexpected uptick in sending people to the hospital over the past year. How does vaping work, and how does it compare to traditional smoking? What can you vape? When people are sucking on USB drives, was that actually them vaping or are they just dumb? We'll get into it! Remember though! We're not a medical advice podcast (those probably don't exist). Don't get medical advice from a podcast, people. References:https://www.mdpi.com/1660-4601/15/9/1853/htmhttps://academic.oup.com/ntr/article/19/10/1224/2631648#113610483https://www.bbc.com/news/business-44295336https://www.nytimes.com/2019/11/08/health/vaping-illness-cdc.htmlhttps://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.htmlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363846/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930618/https://e-cigarettes.surgeongeneral.gov/documents/surgeon-generals-advisory-on-e-cigarette-use-among-youth-2018.pdfhttps://chemrxiv.org/articles/Potential_for_Release_of_Pulmonary_Toxic_Ketene_from_Vaping_Pyrolysis_of_Vitamin_E_Acetate/10058168https://cancerres.aacrjournals.org/content/early/2019/10/26/0008-5472.CAN-19-2997.full-text.pdf
1:02:18
November 18, 2019
SPAAAACE!
On this week's episode, Sean and Nathan explore the human side of outer space! What happens to our bodies in microgravity? What are galactic cosmic rays? Will Disney own the Lunar Gateway Space Station?! Listen to find out, more or less!CORRECTION: Sean messed up! At a certain point, when discussing Van Allen Belts, Sean states that he thinks a portion of the International Space Station's flight path may slightly touch the edge of the inner Van Allen Belt. N O P E ! The ISS hugs the Earth pretty close, and never really gets nearby the Van Allen dudes. Try to like, actually read something next time, Sean.If you have other space stuff you know and want to tell us about, or if we got something else wrong, or if Nathan offended you, please contact us! On Twitter we are @dishpodcast, or you can email us at petridishpod at gmail.com. Please rate and review us on stuff, and consider supporting our work over at patreon.com/petridish!References:https://www.nature.com/articles/s41598-019-42829-zhttps://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.1647https://en.wikipedia.org/wiki/NASA_spinoff_technologieshttps://link.springer.com/article/10.1007/s00198-012-2243-zhttps://www.nature.com/articles/s41526-017-0013-0https://link.springer.com/content/pdf/10.1007/978-3-319-50909-9_23-1.pdfhttps://www.nature.com/articles/s41598-019-50311-zhttps://www.nasa.gov/sites/default/files/atoms/files/space_radiation_ebook.pdfhttps://www.nasa.gov/feature/goddard/real-martians-how-to-protect-astronauts-from-space-radiation-on-marshttp://www.nifs.ac.jp/report/NIFS-886.pdf
1:11:08
November 11, 2019
Bite Me: Ticks and Mosquitoes
Spooky episode 13 is just dropping just a few days after Halloween! This episode is about disease vectors -- specifically ticks, mosquitoes, and the diseases they carry!Learn about how climate change is somehow going to make this stuff worse too! Find out which hemorrhagic fevers are percolating in those little critters.Sponsors: RAGE SALON; SUCKERS - The Sexy Vampire Dating App References:https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2672.2009.04598.xhttps://www.cdc.gov/ticks/tickbornediseases/https://www.cdc.gov/features/stopmosquitoes/index.html
1:08:05
November 4, 2019
Mind-Machine Interfaces
This weeks episode is a spooky sci-fi romp about how we're hooking up brains to computers and minds to machines back to minds again! Except it is all real science! Tune in to hear Nathan and Andrei tell Sean he's crazy, learn what Elon Musk is doing with his latest company, and whether this technology is going to destroy humanity before CRISPR does. For some visual references, I highly recommend this article by "Wait But Why": https://waitbutwhy.com/2017/04/neuralink.htmlQuantum shit is not really Sean's expertise, but this article specifically was what we was referring to when he suggested photosynthesis may involve quantum stuff: https://www.cell.com/trends/plant-science/pdf/S1360-1385(18)30049-9.pdf References:https://stm.sciencemag.org/content/8/361/361ra141.fullhttps://www.nature.com/articles/nature10489https://www.biorxiv.org/content/10.1101/703801v4.fullhttps://www.wired.com/story/brain-machine-interface-isnt-sci-fi-anymore/https://www.cell.com/neuron/pdfExtended/S0896-6273(17)30703-1https://www.nature.com/articles/nature10489https://www.nature.com/articles/s41598-019-41895-7https://www.nature.com/articles/s41598-017-10957-zhttps://www.quantamagazine.org/the-maestro-of-memory-manipulation-20160623/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681944/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907333/http://nerve.bsd.uchicago.edu/FB/NatureReviews.pdf
47:05
October 28, 2019
Crispy CRISPRs and Gene Editing: Part 2
Part two of CRISPR and genetic editing! This time, we talk about what plants and animals we have already CRISPR'd! Also, we discuss CRISPRs in the context of human health. Then, at the insistence of Nathan and Andrei, Sean is forced to discuss the ethical conundrums that come up surrounding the democratization of genetic modification. Nathan starts this episode out with a trigger warning about GMOs, but a less facetious trigger warning for this episode is that we discuss CRISPR and genetic modifications in the context of bioterrorism later in the episode (48:30-55:10), so if for whatever reason you find such things hard to listen to, you know which chunk to skip!Sean mentions silkworms as an organism that has been successfully CRISPR'd, but missed a paper that wasn't just proof of concept -- they shoved in spider silk genes and make a hybrid silk, which is super cool! Stuff is getting CRISPR'd all the time, and new forms of CRISPR are getting engineered in labs all over the world, so this episode is pretty much immediately out of date, but whatever, whaddya gonna do.If you have a gene you want to CRISPR, or want to yell at us for misrepresenting something, tweet us @dishpodcast or email us at petridishpod at gmail.com! Check us out on patreon.com/petridish for early release of episodes and some other kinds of stuff.References:https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177966https://onlinelibrary.wiley.com/doi/full/10.1111/pbi.12832https://onlinelibrary.wiley.com/doi/full/10.1111/pbi.12927https://onlinelibrary.wiley.com/doi/full/10.1111/jipb.12620https://www.nature.com/articles/s41598-018-34104-4http://www.plantphysiol.org/content/174/2/935.fullhttps://www.sciencedirect.com/science/article/pii/S1359511316309047https://www.nature.com/articles/cr2013146https://science.sciencemag.org/content/357/6357/1303.abstracthttps://www.sciencedirect.com/science/article/pii/S0965174816301394https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1144-4#Sec1https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106718#abstract0https://www.nature.com/articles/srep13878https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643211/https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108622https://www.nature.com/articles/nbt.3439https://www.nature.com/articles/nbt.3473https://www.embopress.org/doi/full/10.15252/embj.201899243https://www.nature.com/articles/cr20189https://www.cell.com/molecular-therapy-family/molecular-therapy/pdfExtended/S1525-0016(16)45428-6https://synbiobeta.com/crispr-clinical-trials-a-2019-update/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414166/https://academic.oup.com/jlb/article/3/2/413/1751234#98305641https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058482/https://www.nature.com/articles/s41467-018-05843-9https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779287/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278802/https://www.nature.com/articles/s41580-019-0131-5https://www.nature.com/articles/s41592-019-0508-6https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145266/
1:03:22
October 21, 2019
Crispy CRISPRs and Gene Editing: Part 1
Tenth episode of Petri Dish! Going to be honest, didn't think we'd make it this long. Sean and Nathan have a special guest for this episode, Andrei Daye. He's a dude who has read some stuff about CRISPR-Cas9 and how it is a --r e v o l u t i o n a r y-- technology, and wanted to know more! In case you hadn't heard, CRISPR-Cas9 is the hot new way to genetically modify DNA, and has been used in labs for all sorts of research including the controversial CRISPR-ing of those twins in China!But this episode (part 1 of 2) is about the nitty gritty of how CRISPR works and what its limitations are. Something Sean didn't get to go into but wanted to (Nathan rushed him) was that there are other members of the Cas endonuclease family that are proving to be very useful, like Cpf1, Cas3, Cas13 -- not to mention that Cas9 from different bacterial species can have different properties! So much stuff to know! References:https://www.nature.com/articles/cr201776https://www.sciencemag.org/news/2019/04/powerful-crispr-cousin-accidentally-mutates-rna-while-editing-dna-targethttps://www.nature.com/articles/s41467-018-06129-whttps://www.nature.com/articles/s41467-018-05477-xhttps://www.nature.com/articles/s41598-019-40181-w
42:43
October 14, 2019
Extremophiles!
Our animal episodes seem popular, so episode 9 is a return to silly beasties -- in this case Sean and Nathan are talking about organisms that like to live in EXTREME environments, organisms called extremophiles.Sean and Nathan discuss the plural of octopus, with Sean starting out wrong with octopi (wrong!), Nathan offering octopussies (hmm) then switching to octopuses (best accepted answer). Sean tosses in octopodes, which is the correct plural form based on the etymology, but pretty much no one says it.Sean mentions at one point that at some depths amphipods would normally have their exoskeletons dissolve, but H. gigas is an amphipod that secretes an aluminum hydroxide gel over their exoskeleton to protect it. Which is metal. References:https://www.pnas.org/content/111/12/4461https://www.sciencedirect.com/science/article/pii/S0967063716300656?via%3Dihubhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206710https://www.sciencemag.org/news/2019/03/these-intrepid-crickets-hawaii-s-lava-home-sweet-homehttps://www.nature.com/articles/310225a0.pdfhttps://www.pnas.org/content/104/36/14401.shorthttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187170/https://www.sciencemag.org/news/2019/06/space-station-mold-survives-200-times-radiation-dose-would-kill-human
56:44
October 7, 2019
The Origin of Life
This week Nathan and Sean discuss the origin of life on Earth! Every cell in your body came, ultimately, from the zygote that was made when your dad’s sperm wiggled its way into your mom’s egg. And those little dudes came from another cell, and another, leading all the way back in time - a physical chain of cell divisions leading back to that very first cell. But what existed in the moments before that? Where did that cell come from?Error Thingy: Nathan asked Sean for a timeline on the origin of life, and Sean low-balled it at 3 billion years ago, which is a little short of the current scientific estimates, which place the first cellular life as emerging as recently at 3.5 billion years ago and as far back as 4.2 billion years ago. Given that the Earth formed about 4.5 billion years ago, that could mean that life got going pretty quickly. We’ll see how those estimates hold up as our scientific knowledge expands!Contact us on twitter @dishpodcast or via email petridishpod at gmail.com! Sign up for our patreon www.patreon.com/petridish and rate us on your podcast app!  Some References:https://www.pnas.org/content/114/43/11327.fullhttps://www.mdpi.com/2075-1729/5/1/294/htmhttps://www.sciencedirect.com/science/article/pii/S0960982215006818
46:00
September 30, 2019
Climate, It Is (Still) A-Changin' Part 2 Redux
Woah woah, we got the end of our first little microseries -- this time wrapping up CLIMATE CHANGE. In this episode, Sean tries to convince Nathan that doomsday scenarios are not cool, they're serious business. The dudes walk through the different potential climate scenarios, and some of the potential ways we can mitigate and reverse climate change. If you thought the first episode was dismal, this one really kind of turns it around near the end, sorta. Yeah!Errors n stuff: Nathan loves asking Sean what metric stuff is in USA-units, and Sean got one wrong -- he said 1.5C was 'a little under 4 degrees F', which is dum dum talk because every degree Celsius is 1.8 degrees Fahrenheit, so 1.5C is 2.7F. But whatever man, like, sometimes numbers are hard for some people.If you want to hit us up, email us at petridishpod at gmail.com or tweeters at us @dishpodcast because we do that now. Sign up for our Patreon at www.patreon.com/petridish to help validate our existence! Thanks for listening, everyone! References:https://www.ncbi.nlm.nih.gov/pubmed/27794122https://www.ipcc.ch/reports/http://www.srmgi.org/what-is-srm/http://lsce-datavisgroup.github.io/CO2emissions/https://science.sciencemag.org/content/365/6448/76
56:19
September 23, 2019
Climate, It Is A-Changin'
This week is part one of our two-part series on CLIMATE CHANGE. For part one, Sean and Nathan talk about what is causing climate change and how humans are involved in all of that. Part two (coming next Monday!) covers the different scenarios for what the world could look like in the year 2100, and what we can do to combat climate change! Stay tuned!In the episode, Sean praises China for building a lot of renewable energy, but he didn't know how aggressively India has been expanding their renewable energy capacity (https://reut.rs/2SmotAv). Also, in the episode Sean and Nathan discuss electrification of rural areas, an important variable in the emissions-reduction equation. India has made big strides in electrifying rural areas in the past few years, and nearly all households now have electricity for part of the day. The challenge now is getting them electricity for more of the day, ~50% of rural households have electricity for about half the day. That's better than nothing! But it suggests the grid may be stressed when they need it most, like to help with cooling during heat waves (or to help avoid food spoilage, preservation of drugs/vaccines and stuff, etc).This episode also features listener responses to episode 4 on acupuncture!Podcasts are an audio format, but sometimes visual learning is way more convincing, so check out some beautiful graphics here: https://visme.co/blog/climate-change-facts/Email us at petridishpod -at- gmail.com! Tweet at us @dishpodcast! Sign up on patreon: patreon.com/petridish !Ads for this episode: Rickrods - the sexy rickshaw service | Kruger - auto-edits podcasts to make them sleep-friendly References:This time around, pretty much everything was pulled from IPCC reports (they are super long and comprehensive, check them out!)https://www.ipcc.ch/reports/I recommend the more recent report on keeping things to 1.5 C (https://www.ipcc.ch/sr15/), though for background info the AR5 report is nice (https://www.ipcc.ch/report/ar5/syr/)
43:13
September 16, 2019
Elephants: TREE KILLERS!
Episode 5 of PETRI DISH! This episode is a prequel of sorts to our upcoming 2 part series on CLIMATE CHANGE (oh no!). In this episode, Sean tries to discuss ECOSYSTEM ENGINEERS with Nathan, who keeps calling these critters Environmental Engineers, which is 50% right. He seriously did it multiple times, just couldn't say ecological.Anyway, what's up with these engineer guys? They're animals (including humans!) that shape, maintain, and even destroy ecosystems on a big enough scale to impact the world around them -- changing the landscape, the plants, and the kinds/number of species that live around them. Listen as we talk about megaherbivores like the Elephant, smaller dudes like beavers, even smaller dudes like termites, and then wrap it up with some navel gazing about humans!Email us questions or comments about episodes at petridishpod -at- gmail.com. Hit us up on Patreon at patreon.com/petridish, where $1 a month earns you the patron gift of surprising the shit out of Sean, Nathan, and Stacey. References! Does anyone ever look at these? Some of them could be fun...https://www.cambridge.org/core/services/aop-cambridge-core/content/view/D44E0079BFF2661218B93083F070B562/S0266467498000364a.pdf/moundbuilding_termite_macrotermes_michaelseni_as_an_ecosystem_engineer.pdfhttps://onlinelibrary.wiley.com/doi/full/10.1111/fwb.12487https://www.pnas.org/content/113/23/6388.fullhttps://www.theatlantic.com/magazine/archive/2002/03/1491/302445/https://link.springer.com/article/10.1007/s10682-016-9821-zhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/9781118858615https://academic.oup.com/jmammal/article/98/3/603/3855617https://www.frontiersin.org/articles/10.3389/fevo.2018.00003/full#B74https://www.sciencedirect.com/science/article/pii/S0169555X1100314Xhttps://www.journals.uchicago.edu/doi/abs/10.1086/285824https://www.nature.com/articles/srep32807https://link.springer.com/article/10.1007/s10021-007-9109-9https://onlinelibrary.wiley.com/doi/full/10.1111/j.0030-1299.2004.13139.xhttps://bioone.org/journals/Southeastern-Naturalist/volume-3/issue-4/1528-7092(2004)003[0583:CONAAA]2.0.CO;2/Characterization-of-Natural-and-Artificial-Alligator-Holes/10.1656/1528-7092(2004)003[0583:CONAAA]2.0.CO;2.full
48:11
September 9, 2019
Stick It To Me
Sean and Nathan wrestle with their doubts over acupuncture in the face of its glorious and undeniable efficacy! Learn about what the current science is on whether acupuncture does anything, what it could be physically doing (if anything at all), and a bit about the history of acupuncture as Nathan demonstrates his historian chops. Check out our patreon page!patreon.com/petridish References:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192271/https://www.nature.com/articles/srep16776#discussionhttps://www.nature.com/articles/srep30675#discussionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467968/https://www.sciencedirect.com/science/article/pii/S0266435603002420?via%3Dihubhttps://bioone.org/journals/Freshwater-Reviews/volume-4/issue-1/FRJ-4.1.417/Medicinal-Leeches-Historical-use-Ecology-Genetics-and-Conservation/10.1608/FRJ-4.1.417.fullhttps://journals.sagepub.com/doi/full/10.1016/j.otohns.2004.07.005 This episode was fake-sponsored by RESTAURANTS -- just generally, like, restaurants that you can go out and eat at. This episode was also fake-sponsored by RAGEQUIT -- your one-stop app for acrimonious divorce!
52:13
September 2, 2019
Strange Animals and How To Make Them
What do the duck-billed platypus, antarctic toothfish, and sleepy lizard have in common? They exist, they're weird, and it is evolution's fault. In this episode, Sean and Nathan take a very very small survey of weird wildlife and some of the evolutionary forces behind their oddness.Check out our patreon page! www.patreon.com/petridishContact us about corrections and/or questions at petridishpod at gmail.comRate us on iTunes (we're up on iTunes now!), and/or check us out on Stitcher, Google Play, Spotify, or whatever dude. References:https://advances.sciencemag.org/content/2/10/e1601329https://www.cell.com/current-biology/fulltext/S0960-9822(08)00665-9https://onlinelibrary.wiley.com/doi/full/10.1002/dvdy.23887https://www.pnas.org/content/94/8/3485https://onlinelibrary.wiley.com/doi/full/10.1562/2006-02-24-IR-813https://jeb.biologists.org/content/213/12/2048
51:32
August 26, 2019
Petri Beef
Learn more about the future of meat on the second episode of PETRI DISH. Sean and Nathan discuss lab-grown meat, the not-yet-in-stores futuristic food option that involves growing animal cells in a lab and grinding them up for dinner! Korean Human LCD GIF: https://i.imgur.com/Cnd9rMs.gifvSmall Error Note! At 12:55 Sean says 'cellulose' but he was being dumb -- he meant 'collagen'.References for readin'https://www.sciencedirect.com/science/article/pii/B9780081007228000127https://www.sciencedirect.com/science/article/pii/B9780081005934000175
45:19
August 17, 2019
Baby Got Gut
Hi Everyone! Welcome to the inaugural episode of PETRI DISH. In this episode, Sean and Nathan discuss what is living inside you -- the wonderful and ever-expanding world of the gut microbiome. The microbiome seems to affect things ranging from obesity and diabetes of Alzheimer's and allergies, and we do our best to dip our toes into the big scientific ideas involved in this microscopic world. We'll be trying to use these episode notes to include some reading, if people are feeling scientifically inclined!  *The Hologenome Concept: Human, Animal and Plant Microbiota Rosenberg, Eugene; Zilber-Rosenberg, Ilana https://www.springer.com/gp/book/9783319042404  *Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice Zhan, Gaofeng et al https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046237/
54:42
August 12, 2019