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Physionic

Physionic

By Nicolas Verhoeven
This podcast is dedicated to weekly teachings about your body. You will learn nutrition and physiology in a science based manner.

You can find more *free* science based content by searching "Physionic" on YouTube, Facebook, and Instagram. Learn your body!

Books, Courses, and Hire Me: www.physionic.org
YouTube: bit.ly/2JUjXVt
Facebook: bit.ly/2PlIOaB
Instagram: bit.ly/2OBFe7i
Email List: bit.ly/2AXIzK6
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Fractalkine: A marker for Alzheimer's and Neuroinflammation
In this episode, I discuss a molecule I ran across when listening to the Joe Rogan Experience. This molecule, known as fractalkine, has some unique characteristics and potential implications in a series of different diseases and brain related health outcomes - mostly related to inflammation in the brain. Review: https://pubmed.ncbi.nlm.nih.gov/26084002/ My Creatine Book and Course: http://bit.ly/3sfLLJN YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
32:43
January 13, 2021
Three UNKNOWN Benefits of Creatine [Muscle, Brain, and Inflammation]
In this episode, we briefly discuss three ways that creatine positively affects us in muscle, the brain, and inflammation. I also introduce my first paid content that I spent most of 2020 working on, as well as a new website for your viewing pleasure - it was a busy 2020 for me! Creatine Book and Course: https://www.physionic.org/booksandcourses Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
22:14
January 6, 2021
ASP: The Ketogenic Fat Storage Hormone
In this episode, I go into a bit more detail on a topic I've just started releasing content on (in video form). This subject is on a hormone that also leads to fat storage, much like insulin, yet many keto espousing gurus either ignore or are not aware of it; this is convenient, since this hormone is stimulated by fat consumption, not carbohydrate consumption (the exact anti-thesis to insulin). Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
28:51
December 30, 2020
Chrono nutrition: Intermittent Fasting improves Insulin Sensitivity INDEPENDENT of Calories
In this episode, we'll be diving head long into a study investigating the first slice of "chrono nutrition" on Physionic. I love this study, because they do several things really well and give us some clear answers regarding intermittent fasting and its impact on insulin sensitivity *independent* of calorie intake (finally!). Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528549/pdf/nqaa192.pdf Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
30:51
December 16, 2020
Three Mechanisms of Muscle Growth
In this podcast, I decided to jump into an area I've created a decent amount of isolated content and put it into one place. I go into a bit of depth, but not complete depth into three mechanisms of muscle growth - from the classic "muscle damage" to metabolic stress. Knowing this information can easily help us understand how to create training programs that aren't centered around old fashioned thinking - something I'll certainly touch on more, in the future. Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
32:54
December 9, 2020
Nutrition for Depression: Obesity, Epigenetics, and Tryptophan (yes, the stuff in turkey)
In this episode, we'll be diving into our third and final part of our "Nutrition on Depression" podcast wherein we'll be touching on depression's link in obesity, epigenetics, and the amino acid tryptophan (the same stuff found in turkey, and many other foods). Hopefully you find some, if not all, the information useful and informative. If you'd like to see the visuals, check out the video version of the podcast, as well. Study: https://www.nature.com/articles/s41380-020-00925-x Video (after 10am ET): https://youtu.be/Nxe9AeVlblM Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
30:26
December 2, 2020
Nutrition for Depression: The HPA Axis, Brain Derived Neurotrophic Factor, and More [Part 2]
In this episode, we continue our dive into these different nutrients and nutritionally linked reasons why people have worsening depression and what to do against it, nutritionally. This is part 2 of a 3 part podcast series discussing nutrition and its relationship to depression. I'll go into the microbiome, cortisol release from the HPA axis, and BDNF on brain cell growth. Study: https://www.nature.com/articles/s41380-020-00925-x Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
47:50
November 25, 2020
Nutrition on Depression: Nutrients that Help [Part 1]
In this episode, I begin with part 1, wherein we'll be discussing how depression is linked to inflammation, mitochondrial dysfunction, and oxidative stress, as well as several nutrients that can help reduce these effects negatively affecting mental health. Study: https://www.nature.com/articles/s41380-020-00925-x Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
58:25
November 18, 2020
Fasting on Skin Health & Skin Aging: A Review
In this episode, I'll be trying my best to make sense of a pretty "all over the place" scientific review that attempts to make sense of how fasting (and calorie deficits) affect skin health, as well as aging. Video Version: https://youtu.be/ihV7hOhAk58 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
42:35
November 11, 2020
Caffeine: Does it make us less insulin sensitive?
In this episode, we dive into a study that investigates the effect caffeine has on insulin sensitivity, but also on a few other parameters, like blood pressure, catecholamines, and free fat. Study: https://care.diabetesjournals.org/content/25/2/364.full-text.pdf Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
39:56
November 4, 2020
Creatine on Fat Metabolism, Thermogenesis, ft. Alec Chaves
In this episode, I have the absolute pleasure of welcoming a good friend of mine back to the podcast to discuss a paper he picked out looking at a unique way that creatine affects our fat cells - specifically, the mitochondria within fat cells. Creatine Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656041/ Alec's Podcast (Physiology Forum): Apple: https://podcasts.apple.com/us/podcast/the-physiology-forum/id1524358256?id=1524358256&ign-mpt=uo%3D4 iHeartRadio: https://www.iheart.com/podcast/269-the-physiology-forum-63366437/ Podbean: https://thephysforum.podbean.com/ Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
1:07:59
October 28, 2020
Women vs Men: Who Gains Muscle Strength Faster?
In this episode, we dive into an extremely simple study that investigates how quickly men and women, compared against one another, gain muscle strength from a resistance training program. Not only that, it touches on some interesting perspectives related to hormones and how the lack of testosterone in women may not be as detrimental as one might imagine - tune in and find out! Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756754/ Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
29:39
October 21, 2020
10 Day Water Fast INCREASES Inflammation, but is that bad?
In this podcast, we'll be going over a study that touched on an interesting discovery between fat cells and our immune system when a person undergoes an extended (10 day) water fast. Study: https://reader.elsevier.com/reader/sd/pii/S2212877820301563?token=8C7127DDF72DF25D84C3810C2A6673547BFB183F9FA75E6692EA9472DCC7CC12A193097F7212AC3D993955B07CAA1405 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
41:57
October 14, 2020
Does Saturated Fat increase Cholesterol and damage your Liver?
In this episode, I do a deep dive into a study that finally tries to answer if saturated fat increases our cholesterol levels, independent of weight gain. Not only that, it also investigates the impact it has on the liver in terms of fatness - does it cause fatty liver disease? Study: https://academic.oup.com/jcem/article/104/12/6207/5540968 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
57:57
October 7, 2020
Alternate Day Fasting on Cholesterol, Muscle, and Fat-centric Hormones
In this episode, I'll be taking you through a study on alternate day fasting and its affects on cholesterol, fat, muscle, and three unique hormones - all in people without cardiovascular issues, which makes this study that much more unique. Study: https://onlinelibrary.wiley.com/doi/10.1038/oby.2010.54 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
45:20
September 30, 2020
A Light Review of Body Weight "Set Point" Theory
In this podcast, I brush across a variety of concepts and information related to the hypothesis of "body weight set point" that espouses the idea that the body sticks to roughly the same set point in body weight when we attempt to change our weight, the body fights against that imposed change - why? What mechanisms and reasons might there be? Is there a better theory? Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990627/#bib-010 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
53:14
September 23, 2020
The Consequences of Extreme Dieting & Low Body Fat
In this episode, I'll be walking us through a case study that recently released on a natural bodybuilder that was followed and measured by researchers for 12 months. They wanted to know how extreme dieting to low single digit body fat would affect testosterone, thyroid hormone, muscle mass, metabolism, and more, and if there were any negative effects, how long would it take to recover? Study: https://pubmed.ncbi.nlm.nih.gov/32898035/ Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
54:02
September 16, 2020
High Fat vs High Carb Diets - Which is better for Health? (Blood Pressure, Cholesterol, Leptin, and more)
In this episode, we'll be getting into a study looking at the ketogenic (high fat) diet and its comparison to a calorie restricted low fat diet on various markers of health. Study: https://academic.oup.com/jcem/article/88/4/1617/2845298 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
31:28
September 9, 2020
Can you get coronavirus more than once? Yes. [New Study]
In this episode, I'll be explaining, based on a brand new case study, why the risk for re-infection is present, and what this means for the future of vaccines and herd immunity. Study: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1275/5897019 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
23:12
September 2, 2020
Do Artificial Sweeteners and Sugar cause Weight Gain and Cravings? A Study weighs in.
In this episode, we cover a study investigating if 4 different artificial sweeteners (Sucralose, RebA, Saccharin, and Aspartame) cause weight gain, insulin issues, spikes in blood sugar, cravings, and more. Study: https://academic.oup.com/ajcn/article/109/5/1288/5475055 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
25:51
August 26, 2020
Supplementing Coenzyme Q10 and migraines... is there a benefit?
In this episode, we'll be looking at a brief clinical trial looking at coenzyme Q10 (CoQ10, ubiquinone) and its affect on migraines in clinically evaluated migraine sufferers. If CoQ10 works, how much was used? How beneficial is it? Are there caveats? All that and more is covered here. Study: https://www.semanticscholar.org/paper/Efficacy-of-coenzyme-Q10-in-migraine-prophylaxis%3A-A-S%C3%A1ndor-Clemente/a3d4701fc58f7747a1cff3ddcd978a0794a50dc2 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6
22:25
August 19, 2020
Is Intermittent Fasting hurtful to Heart Health? Maybe.
In this episode, we'll be diving into a study investigating the role intermittent fasting has on a series of health markers, but specifically on cholesterol and blood pressure - it's not all good news, or is it? Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645638/ Books, Courses, and Hire Me: www.physionic.org YouTube: http://bit.ly/2JUjXVt Facebook: http://bit.ly/2PlIOaB Instagram: http://bit.ly/2OBFe7i Email List: http://bit.ly/2AXIzK6
28:27
August 12, 2020
Plant and Animal Protein associations to Cancer, Heart Disease, and Mortality
In this episode, I discuss a meta-analysis looking into the associations between animal and plant based proteins, as well as total protein, and their relationships to cancer, cardiovascular disease (heart disease, stroke, etc.), and overall mortality. Is plant protein superior? Study: https://www.bmj.com/content/370/bmj.m2412 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
30:36
July 29, 2020
Making Sense of the Microbiome, ft. Bern Monari
In this episode, I had the pleasure of having a friend and microbiome researcher Bern Monari on to educate us on the microbiome and the research therein. I hope this podcast ends up interesting, because I certainly found it to be, and Bern adds quite a bit to my knowledge of the matter. Enjoy! Bern's LinkedIn (to ask questions): https://www.linkedin.com/in/bernadinemonari/ YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i Podcast: http://bit.ly/2PThKz0 Email Opt-In: http://bit.ly/2AXIzK6 Facebook Page (Poll Question): http://bit.ly/2PlIOaB Patreon: http://bit.ly/2OBBna0   Bern's References: 1. Marchesi JR, Ravel J. The vocabulary of microbiome research: a proposal. Microbiome. 2015;3:31. 2. NIH Human Microbiome Project defines normal bacterial makeup of the body [press release]. nih.gov: NIH, 2015-08-31 2015. 3. Ochman AHM, Steffen F, Michael LW, Anne EP, Beatrice HH, Howard. Social behavior shapes the chimpanzee pan-microbiome. Science Advances. 2016;2(1). 4. Engel P, Kwong WK, McFrederick Q, et al. The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions. mBio. 2016;7(2):e02164-02115. 5. Rudman SM, Greenblum S, Hughes RC, et al. Microbiome composition shapes rapid genomic adaptation of Drosophila melanogaster. Proceedings of the National Academy of Sciences. 2019;116(40):20025-20032. 6. Edwards VL, Smith SB, McComb EJ, et al. The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection. mBio. 2019;10(4):e01548-01519. 7. Jobira B, Frank DN, Pyle L, et al. Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota. The Journal of Clinical Endocrinology & Metabolism. 2020;105(6). 8. Luu M, Monning H, Visekruna A. Exploring the Molecular Mechanisms Underlying the Protective Effects of Microbial SCFAs on Intestinal Tolerance and Food Allergy. Frontiers in Immunology. 2020;11(1225). 9. Allegretti J. Stool transplants are now standard of care for recurrent C. difficile infections - Harvard Health Blog. health.harvard.edu. https://www.health.harvard.edu/blog/stool-transplants-are-now-standard-of-care-for-recurrent-c-difficile-infections-2019050916576. Published 2019. Updated 2019-05-09. Accessed2020. 10. Types of Infections After Stem Cell or Organ Transplants. https://nyulangone.org/conditions/infections-after-stem-cell-or-organ-transplants/types. Published 2020. Accessed 07/16/2020, 2020. 11. Cdc. Reports of Selected E. coli Outbreak Investigations | E. coli | CDC. 2020. https://www.cdc.gov/ecoli/outbreaks.html. Accessed 2020-02-26T02:39:54Z. 12. van de Wijgert JHHM, Verwijs MC, Agaba SK, et al. Intermittent Lactobacilli-containing Vaginal Probiotic or Metronidazole Use to Prevent Bacterial Vaginosis Recurrence: A Pilot Study Incorporating Microscopy and Sequencing. Scientific Reports. 2020;10(1):1-15. 13. Yong E. You're Probably Not Mostly Microbes. The Atlantic. 2016-01-08, 2016.
36:22
July 22, 2020
Behind the Scenes of a CoVID-19 Vaccine, Side Effects, & Science Explained, ft. David Rach
In this episode, I had the pleasure of having a fellow researcher and class mate David Rach on the podcast to discuss his experience as a participant in a CoVID-19 vaccine trial. However, not only that, he is getting his PhD in Microbiology and Immunology, so he was able to discuss some of the science behind vaccine development, as well as the preliminary results of the trial he was in. David's Info Twitter: @DavidRach2 Facebook Post on the Topic: https://tinyurl.com/yazocyla Vaccine Trial Data: https://www.medrxiv.org/content/10.1101/2020.06.30.20142570v1.full.pdf?fbclid=IwAR3guvvo_TdhDAh1tDZwTUH5rRH-p-I7sanyfoM9Dp3-8wK-cydchyNrmEU More info: coronaviruspreventionnetwork.org
35:59
July 15, 2020
Fiber, Stomach Bloating, and Potential Solutions
In this episode, we'll be taking a look at some information on fiber, but more poignantly focused on stomach bloating and how it relates to fiber, as well as some things to consider to lower bloating from the lack or incorrect fiber intake. Fiber & Gas Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774297/ YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0
19:11
July 8, 2020