The development of brain-machine or brain-computer interfaces (BCIs) approaches an inflection point; not just the pace of BCI progress, but also the capabilities and willingness to explore the field of neurotechnology have accelerated dramatically in recent years.

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On this episode of the TomorrowScale podcast, we speak with the scientist and entrepreneur leading a startup developing implantable connections between our brains and computers. Our guest is Dr. Matt Angle, CEO of Austin, TX based Paradromics. He and his team just announced the ARGO system: a brain computer interface consisting of an implantable microwire electrode array with over 10,000 channels per square centimeter. At 26 Gigabits per second they have demonstrated the largest ever electrical recording of cortical activity in preclinical studies. At 65,536 parallel electrode channels, Paradromics has opened the largest window into the senses and doorway into the brain to date.

In our conversation, we discuss the science of brain computer interface technology and look toward the potential clinical and consumer applications for melding humans and machines. Also, Matt candidly addresses the balance between the hype and hurdles that facing Paradromics and the neurotechnology field at large: Everything from the immense engineering and computation challenges, to the systemic issues holding back hard tech commercialization, a neurotechnology competitive playing field that now includes billionaire pet projects, and what it was like moving their company out of Silicon Valley.

This is the TomorrowScale podcast. Hosted by Justin Briggs.

Paradromics: https://paradromics.com

ARGO Announcement: https://paradromics.com/news/paradromics-unveils-the-largest-ever-electrical-recordings-in-cortex/

"The Argo: A 65,536 channel recording system for high density neural recording in vivo" (Sahasrabuddhe 2020, bioArxiv preprint): https://www.biorxiv.org/content/10.1101/2020.07.17.209403v1

Some of the labs mentioned on the show: 1, 2, 3,

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The TomorrowScale Podcast was created to showcase scientists and entrepreneurs who are building science-based businesses, and to hear stories from the benches and in the trenches of research & development. The views expressed by the host and guests are their own, and the content of this show should not be considered legal, tax, or investing advice. Thanks to our guests for sharing their time and knowledge with us. Thank you for listening. Please science responsibly.

Human on a Chip - Emulate

TomorrowScale PodcastBy Justin BriggsSep 16, 2021