Science Talks: A conversation hosted by the University of Arizona’s BIO5 Institute
By BIO5 Institute
In our Science Talks podcast, we share the important research and innovation happening at the University of Arizona BIO5 Institute and how it impacts all of us, our state, and our world. BIO5 brings together hundreds of multifaceted experts that include world-class bioscientists, engineers, physicians, and computational researchers in a team science environment designed to creatively solve difficult problems.
Episode 20: Spearheading transdisciplinary bioscience research
Transdisciplinary research unites researchers from different backgrounds to integrate and move beyond discipline-specific approaches to address today’s grand bioscience and biomedical challenges. Dr. Taylor Edwards, clinical manager and development scientist at the University of Arizona Genetics Core, shares how the UAGC core facility brings together researchers and samples across the university to tackle projects spanning COVID-19, environmental science, and more. Though the projects vary, Edwards says that a common theme of DNA unites them.
October 11, 2021
Episode 19: Drugging the “undruggable” targets in GI cancers
Gastrointestinal cancers collectively represent one of the greatest public health challenges, accounting for more than one-quarter of all global cancer cases and more than 35% of all cancer-related deaths. Many of these cancers, including pancreatic and biliary, have been historically hard to treat. Dr. Rachna Shroff, Associate Dean of clinical and translational research and chief of GI medical oncology at the UArizona Cancer Center, discusses her genomic profiling approach to developing personalized treatments for cancer patients. She also shares how she supports other researchers and clinicians in connecting their findings at the bench and bedside to discover new therapies through her role as director of the Arizona Clinical Trials Network.
September 27, 2021
Episode 18: Pathogens of the female reproductive tract
Bacteria were among the first forms of life on earth, and while some strains cause infection or spoil food, others are essential to providing nutrients to plants, fermenting foods, and supporting our gut and reproductive health. Dr. Melissa Herbst-Kralovetz, associate professor of basic medical sciences, as well as obstetrics and gynecology at the College of Medicine – Phoenix, explains how the delicate balance between “good” and “bad” bacteria affect the health of the female reproductive tract. She shares how her research will ultimately help to develop better diagnostics, preventatives and treatments for sexually transmitted infections, gynecological cancer, and more.
September 13, 2021
Episode 17: From laboratory research to science communication
Pursuing a doctorate in STEM doesn’t mean one is destined for a life at the lab bench. Dr. Brittany Uhlorn, coordinator of marketing and communications at the BIO5 Institute, shares why she transitioned to science communication after obtaining a doctorate in cancer biology. She also discusses how her training as a bench scientist benefits her new career writing stories for lay audiences and co-hosting Science Talks.
August 30, 2021
Episode 16: Predicting drug toxicity and flood risk with data science
Some of the biggest challenges in STEM are so large that they can’t be addressed at the lab bench. Dr. Walter Piegorsch, director of statistical research & education at the BIO5 Institute and professor of mathematics and public health shares how he uses the power of data science and informatics for environmental and health risk assessment.
August 16, 2021
Episode 15: Tackling neuro-infectious diseases as a physician-scientist
Ever wonder why pregnant people shouldn’t scoop kitty litter? They might come into contact with toxoplasma gondii, a parasite that infects up to one-eighth of the world’s population that can cause lifelong infection in the central nervous system. Dr. Anita Koshy, associate professor of neurology and immunobiology and BIO5 member, talks about her research to better understand this pesky parasite. She also shares her journey to becoming a physician-scientist, and how she spends her time away from the clinic and lab.
August 2, 2021
Episode 14: Transforming through BIO5 engagement
By engaging students in hands-on experiential learning and providing them with a world-class education, these budding young minds can blossom into productive members of the STEM workforce. Ryan Hunt has taken advantage of several opportunities provided by the BIO5 Institute, including the KEYS high school internship program, undergraduate research, and a student job with the public affairs team. Hunt shares how each role within BIO5 has impacted him both personally and professionally. He also talks about his love for art and science, and how the two can be combined to communicate science with researchers and the public alike.
July 19, 2021
Episode 13: Uncovering the role of soil microbes on climate change
Microbes living in the soil play a vital role in global photosynthesis by producing and consuming trace gasses in our atmosphere. Dr. Laura Meredith, assistant professor of ecosystem genomics, genetics, global change, and hydrology and atmospheric sciences, discusses her work to better understand the relationship between microbes, plants, and the atmosphere. She talks about her current field work in Alaska to decipher how this relationship impacts climate change. Dr. Meredith also shares how she thrives as a woman in STEM and how she supports her fellow female colleagues and students.
July 6, 2021
Episode 12: Building self-confidence through near-peer mentorship
High school and undergraduate students are tested academically and personally by lessons learned during these transformative years. While seasoned professionals can help to guide students by sharing their knowledge, near-peer mentors can often have a bigger impact through similar experiences. BIO5 Public Affairs Student Assistant Jordan Pilch discusses how her roles in the KEYS summer internship program - both as an intern and as a mentor - have not only shaped her career path but also taught her a lot about self-confidence and self-efficacy. She also shares how she imparts this wisdom as a facilitator and near-peer mentor for the BIO5 Ambassadors Internship.
June 21, 2021
Episode 11: Giving back through mentorship and opportunity
Budding professionals, especially those representing historically underserved identities, greatly benefit from mentorship and programs designed to advance their educations and careers. Dr. Michael Johnson, assistant professor of immunobiology at the BIO5 Institute, discusses his passion for mentoring and outreach, as exemplified by two successful programs that he’s spearheaded in recent years: the BIO5 Postdoctoral Fellowship and the National Summer Undergraduate Research Project (NSURP).
June 7, 2021
Episode 10: Transforming the textbook into a real-world experience
Most high school students - let alone college students - ever receive the opportunity to apply lessons learned in their STEM textbooks to solving real-world problems. Keep Engaging Youth in Science (KEYS) coordinators Brooke Moreno and Kelle Hyland discuss how the BIO5 Institute’s flagship high school research internship program solves this problem. They’re also joined by two KEYS Crew leaders - BIO5 Outreach and Engagement Specialist Marissa Romero and BIO5 Public Affairs Student Assistant Robyn Pratt - who share what makes this program so unique as they gear up for the launch of 2021 program on June 7.
May 25, 2021
Episode 9: Supporting the next generation of STEM professionals
Not all career paths are linear, and most budding professionals need support along the way. Dr. Uwe Hilgert, associate research professor and director of Industry Relations, Workforce Development and STEM Training at the BIO5 Institute, discusses his career journey from the lab bench to working in education and outreach. He also talks about his essential roles in two Discover BIO5 events and making the transition to a virtual Keep Engaging Youth in Science (KEYS) summer research internship program.
May 10, 2021
Episode 8: Personalizing treatments with the power of computers
In the era of precision medicine, scientists and physicians are constantly looking for ways to innovate and personalize disease treatment. Dr. Yves Lussier, former BIO5 Associate Director and Associate Vice President and Chief Knowledge Officer at UArizona Health Sciences, discusses how technology and a bioinformatics approach can help us better understand diseases like COVID-19 and tailor treatments to each individual.
April 26, 2021
Episode 7: The importance of storytelling and collaboration
Today’s biggest scientific questions cannot be conducted "in a vacuum.” Dr. Kate Rhodes, a postdoctoral fellow in the laboratory of Dr. Maggie So’s lab, shares how the BIO5 Institute fosters the cross-disciplinary work that is necessary to solve these problems. She also talks about her research on a bacterial strain that causes gonorrhea, a highly prevalent sexually transmitted infection. Dr. Rhodes, a two-time recipient of the BIO5 Postdoctoral Fellowship, discusses how she employs storytelling through grant writing and public communications.
April 7, 2021
Episode 6: Viruses, vaccines and advocacy
The emergence of a novel vaccine can be both a scientific triumph and point of uncertainty for the general population. Dr. Robert Jackson, a postdoctoral fellow in the laboratory of Dr. Koenraad Van Doorslaer, discusses his research on human papillomavirus - the most common sexually transmitted virus and cause of 5% of all cancers worldwide. Dr. Jackson, a recipient of the BIO5 and Canadian NSERC Postdoctoral Fellowships, also talks about his passion for communicating the scientific method, or process, to the public, specifically as it relates to sharing the utilities of both the HPV and COVID-19 vaccines.
March 26, 2021
Episode 5: Infecting others with a love for science
Human cytomegalovirus persists in the majority of the population worldwide and is the leading cause of infectious disease-related birth defects. Dr. Felicia Goodrum, a professor of cellular and molecular medicine, cancer biology, genetics, and molecular and cellular biology, discusses her work on this public health concern. She also shares how she “infects” others with a love for science through science communication and public outreach. The self-proclaimed lifelong learner also talks about the importance of a two-way mentorship relationship.
March 11, 2021
Episode 4: Finding our new normal
Now a year into the COVID-19 pandemic, we're eager to return to life as it once was - but is that possible? If not, what does our "new normal" look like? Dr. Bonnie LaFleur, a BIO5 member and research professor of biostatistics, discusses how the different COVID-19 testing methods and vaccination efforts will enable us to one day go back to our old ways of lives. She also stresses that building "social contracts" with those in our inner circle are essential to keeping ourselves and others safe.
February 25, 2021
Episode 3: Pursing wellness amid COVID-19
Over the past year, many have become more interested in ways to support their mental, physical and emotional well-bring. Dr. Floyd "Ski" Chilton, BIO5 member and Director of the Precision Nutrition and Wellness Initiative discusses the upcoming Precision Wellness in the Time of COVID-19 public series that aims to educate the public and help them pursue health, both during the pandemic and for years to come. Chilton also shares how he pursues mindfulness and well-being, and how he imparts these messages on others through his research, outreach and books.
February 10, 2021
Episode 2: Novel treatments for COVID-19
Soon after the pandemic started, more than half a million dollars was rapidly reallocated to supply 13 interdisciplinary teams with immediate funding to pursue basic science, technology, clinical or population-based research projects that directly address COVID-19. Dr. Jianqin Lu, BIO5 member and assistant professor in the College of Pharmacy, discusses his two BIO5 COVID-19 seed grant projects. The first focuses on the use of nanotechnology to improve efficacy and minimize toxicity of anti-malarial drugs against COVID-19, while the second project explores whether enhancing COVID-19 patients’ immune systems can treat their infections.
February 4, 2021
Episode 1: A public health approach to overcoming the pandemic
Soon after the pandemic started, more than half a million dollars was rapidly reallocated to supply thirteen interdisciplinary teams with immediate funding to pursue basic science, technology, clinical or population-based research projects that directly addressed COVID-19. During the course of this and future episodes, we will learn more about the inspiration behind some of the team projects, what the rapid funding allowed them to do, and the progress they have made towards their goals. Dr. Kristen Pogreba Brown, assistant professor of public health specializing in epidemiology and biostatistics joins us to share more about her work on the COVID-19 pandemic.
January 27, 2021