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Brain Explained

Brain Explained

By Abdullah Iqbal
A podcast exploring fresh off the press neuroscience research. Tune in to our podcast for a deep dive interview exploring a research paper or thesis with the scientist themselves. Strengthen your understanding of the brain at the molecular level and gain an understanding of what it's like being a cutting-edge researcher.

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Welcome to Brain Explained!

Brain Explained

How Neurons Know Where To Go With Dr Titas Sengupta
Episode Description This episode is with Dr Titas is looking at retrograde zippering which is another way that neurons are able to correctly grow towards their correct final destination. What exactly does this system involve and how does this work? Listen in to learn all about it and we also explore why the C.elegans is a good model for neuroscience research- depending on the question you are asking. I am also looking for individuals who would be interested in contributing to the blog. It would involve posts about the recent neuroscience that has been published preferably that week. You would try to explain the science in an easy to understand manner and would also want to delve into the significance of the findings. If this is something that interests you I would delighted to hear from you – please join the Brain Explained LinkedIn Contributors Page. Linkto paper Dr Titas Sengupta Twitter page Link to website
March 23, 2022
Tangled Blood Vessels With Dr Ethan Winkler
Listen in to learn more about arteriovenous malformations (AVM) a condition that leads to tangled blood vessels in the brain and spinal cord. This increases an individual’s likelihood of stroke. This week we will be exploring research that profiled the cells the blood vessels to find what changes occurred in these cells compared to normal samples. listen in to find out about this amazing research that could have wide-ranging implications. Dr Ethan Winkler’s Twitter Dr Ethan Winkler’s University Profile The paper 
February 22, 2022
Dancing Molecules and Regenerative Gels with Professor Samuel Stupps
Episode 11 is all about dancing molecules and how they could be used to help improve spinal cord regeneration. Listen in to learn how proteins that move faster are more effective with Professor Samuel Stupps. Link to paper - Professor Stupp’s Lab Website - Prof. Stupp's Twitter- Useful Links:
February 02, 2022
Concussion and Smartphones with Dr Prasanna Acharya
Research looking into the effects of phones and concussions. An odd mix but interesting. Listen in to learn more. We’ll be talking to Dr Prasanna. Link to dissertation work -
January 02, 2022
Special Episode Number 1 - Ketamine with Dr Argel
Episode Description Come and listen to the first special episode. A conversation with Dr Argel who I meet through the Society of Neuroscience. We talk about his journey into neuroscience and his work covering memory and studies into neuroinflammation and ketamine. Lab website Twitter account
December 26, 2021
Team Flow with Professor Mohammad Shehata
Want to know how we work well in teams? Then listen in to the latest episode exploring team flow with Professor Mohammed Shehata. Flow is our ability to enter that state where everything aligns and we are able to focus entirely on the task at hand. - The eNeuro paper (the journal article here) News coverage including The Times Magazine London (here), Psychology Today (here and here), IFL Science (here), TVN (here), Science Alert (here), SciShow News (here), and more (here). - Mohammad Shehata’s LinkedIn - Mohammad Shehata’s Twitter :@Mohamma_Shehata
November 25, 2021
Dopamine, Active Sensing and Blood Flow with Professor David Kleinfield
I’m back on track. Here is the next episode. In this episode we explore dopamine signalling in the brain. Why? Because dopamine is the main signalling compound in your brain for reward. So eat a bar of chocolate, get a new job, pass your exams and you get a dose of dopamine. But the research by Professor David Kleinfield is even more important because it shows that mice can control their release of dopamine, which might explain why we can do things that to others seem strange such as climbing mountains. That isn’t all, listen in to learn about his other research around the role of the vasculature in the brain and how senses work. David Kleinfield lab website The main paper Two other interesting papers (which can be found on his website): Ultra-slow oscillations in fMRI and resting-state connectivity: Neuronal and vascular contributions and technical confounds. Brain microvasculature has a common topology with local differences in geometry that match metabolic load.
October 26, 2021
Neurospirituality with Professor Michael Fergurson
 Episode 6 will be looking at  the brain regions involved in spirituality and Religiosity which is another word for religion. Therefore, I am extremely grateful to give you this unique episode. This episode will be of interest as over 90% of percent of people have some sort of spiritual practice and the other 10% will want to know how the brain is linked to spirituality and religion and what it means. Not only is this research interesting but it can help people make electrical stimulation therapy which is becoming even more common to reach the forefront. Neurospirituality course syllabus: Twitter for Professor Michael Ferguson: Biological Psychiatry article access: Neuromichael YouTube channel:
September 16, 2021
Traumatic Brain Injury with Dr Andrew Pieper
Episode 5 dives traumatic brain injury a disease commonly received after too many blows to the head. How can we protect against this and how exactly is it studied in the lab. If that piques your interest then be sure to check out for we cover this and much more with Dr Andrew Pieper, a researcher in this field from the Harrington Discovery Institute. Link to Dr Andrew Pieper’s Lab Website Link to Dr Andrew Pieper’s LinkedIn Link to paper Brain Explained - Twitter Brain Explained - LinkedIn
June 19, 2021
All About Pain with Dr Franziska Denk
Episode 4 of Brain Explained explores a new theory for understanding pain. Pain, its something we feel often and that many people chronically suffer from with an estimated 40% of people suffering from chronic pain and understanding pain would allow us to help them. That is where Dr Franziska Denk’s Research comes into play. For she is describing a new theory showing that a type of cell called a fibroblasts may be the key player in chronic pain. Listen to the episode to find out how. Link to Franziska Denk’s lab website Link to Twitter page for lab Link to LinkedIn Links to papers: Fibroblasts– the neglected cell type in peripheral sensitization and chronic pain? - A systematic view on the current state of the literature. A transcriptional toolbox for exploring peripheral neuro-immune interactions Sensitization of Knee-Innervating Sensory Neurons by Tumour Necrosis Factor-α Activated Fibroblast-Like Synoviocytes: An in Vitro, Co-Culture Model of Inflammatory Pain. Resources:
May 11, 2021
Cleaning in the Brain, Neuroimaging and Perivascular Spaces with Professor Farshid Sepherband
Episode 3 of Brain Explained explores neuroimaging and blood supply, cleaning in the brain with Professor Farshid Sepherband from The University of Southern California. Why are spaces imaged in the brain and how are they linked to daily life and disease? Listen to find out. In Episode 3 we discuss his recent research into the neuroimaging of the clearance system and blood supply. We discuss his research, opportunities and as always there are a lot of interesting insights. Twitter LinkedIn Further links: Link to Farshid Sepherband’s lab website Link to papers: Perivascular space and BMI/ time of day/ gender, Perivascular space and Parkinson’s Disease, Perivascular space and Alzheimer’s Disease. Neuroimaging resources: LONI pipeline(for image analysis) : Open source python group for neuroimaging: Introduction to biomedical imaging: To learn about basics MRI physics: For MRI related questions: MRI communities - with a lot of resources: ISMRM: OHBM: Farshid’s favourite neuroscience online course:
March 29, 2021
Exploring How the Brain Forms Memories and Stores Language with Professor Chris Petkov
Episode 2 of Brain Explained explores the brain circuits involved in language and memory with Professor Christopher Petkov of Newcastle University. Chris’s work looks at the brain regions involved in language and memory in humans and macaques. We discuss his work, how it is being practically used, the opportunities you have to get involved in this area of research using real data and more. Link to Chris Pektov's Laboratory Website. Link to paper Current Research in Neurobiology  Editorial Introduction to Current Research in Neurobiology.
February 18, 2021
Brain Cholesterol, Oxidative Stress and Alzheimer's Disease with Dr Hemant Mistry
Episode 1 of Brain Explained explores Alzheimer's Disease research with (the now) Dr Hemant Mistry of the University of Sheffield. Hermant's work looks at the role of brain cholesterol in the development of Alzheimer's Disease.  We discuss his work on post-mortem brain tissue, cell cultures, impact of oxidative stress on neurons and more. We also discuss careers which is particularly useful for those wanting to break into the field of neuroscience. Hemant's contact info:
January 01, 2021
Welcome to Brain Explained!
A short introductory episode detailing what Brain Explained is all about.  Twitter - Linkedin - Email - Music Beauty Flow by Kevin MacLeod Link: License:
December 20, 2020