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Preprints in Motion

Preprints in Motion

By Dr Jonny Coates

Science is experiencing a revolution. Preprints have accelerated the sharing of scientific findings and helped to make academia more equitable. Join our host, immunologist and open-science advocate, Dr Jonny Coates, as he explores the freshest science with the early career researchers who did the work; discussing their science, thoughts on academic life, publishing and much more. So sit back and join us as we dive into the fast-paced world of preprints and dismantle the outdated traditional publishing models. Produced and Edited by Dr Emma Wilson, Dr John D Howard & Dr Camila Valenzuela.
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Prachee Avasthi on ASAPbio, Arcadia Science and the open science mission on our one year birthday

Preprints in Motion

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eLife: publishing, community and pushing the boundaries with Michael Eisen & Devang Mehta
eLife: publishing, community and pushing the boundaries with Michael Eisen & Devang Mehta
This week we discuss the big changes occurring over at eLife with Editor in Chief Mike Eisen & original ECAG member Devang Mehta. From Jan 2023, eLife is  focusing on public reviews and assessments of preprints and eliminating accept/reject decisions after peer review. Read more about this new model here: https://elifesciences.org/inside-elife/54d63486/elife-s-new-model-changing-the-way-you-share-your-research Mike Eisen: http://mcb.berkeley.edu/faculty/GEN/eisenm.html Devang Mehta: https://mehta-lab.com/ eLife: https://elifesciences.org/ This episode was produced by Jonny Coates and edited by Camilla Valenzuela. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod, Instagram @Motion_Pod or visit our website; www.preprintsinmotion.com. Find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) & Camila (@Kamo_Valenzuela). Generously supported by ASAPbio (https://asapbio.org | @asapbio_).
01:29:08
January 18, 2023
Xmas special - Battle of the servers, how to choose a preprint server
Xmas special - Battle of the servers, how to choose a preprint server
DISCLAIMER – These servers were reviewed from the approach of a first use instance and may not accurately reflect the full capabilities of each server. Moreover, any comments are opinions only. Preprint servers. There’s an incredibly interesting history behind them (watch this space for more on that next year) but as of 2022 there are over 50 different preprint servers. No wonder it feels like they’re an inescapable topic these days. I mean, we’re contributing to that but hey. Some are highly specialised, such as EcoEvoRxiv (that’s ecology, evolution and conservation), and some are geo-restricted, such as AfriaRxiv. Consideration of preprint servers based on discipline, scope, policies, and readership is relevant to inform where to deposit your preprint, and in turn to maximize visibility for the work and opportunities for feedback from researchers in your specific field. In this episode we take 3 of the top general bioscience preprint severs and put them to battle. We judge each on their: Appearance / ease of use – navigating and submitting Reach /size Journal integrations Additional offerings – public peer reviews, data, printing, links out, attention/metrics Positives of the server Negatives/improvement aspects of the server Why choose this server over the others? Useful links: https://asapbio.org/preprint-servers https://journals.biologists.com/bio/article/11/7/bio059310/276073/A-guide-to-preprinting-for-early-career Some preprint servers in addition to those discussed in the episode: OSF – more of a search engine but very useful bioRxiv/medRxiv Research Square Authorea F1000 Cell Sneak Peak and Preprints with the Lancet Preprints.org This episode was produced by Jonny Coates, Camilla Valenzuela and John Howard and edited by John Howard. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod, Instagram @Motion_Pod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
58:12
December 07, 2022
RNA editing in squid; recoding the proteome with Kavita Rangan
RNA editing in squid; recoding the proteome with Kavita Rangan
This week we discuss RNA editing in cephalopods with postdoc Kavita Rangan. Read the full preprint -> https://www.biorxiv.org/content/10.1101/2022.09.25.509396v1.full This episode was produced by Jonny Coates and edited by Tala Noun & John Howard. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod, Instagram @Motion_Pod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
44:44
November 16, 2022
PreReview: leading the charge in transparent peer review of preprints with Daniela Saderi
PreReview: leading the charge in transparent peer review of preprints with Daniela Saderi
This week we chat with Daniela Saderi, she is the Co-Founder and Director of PREreview (@prereview_), an open project with the mission to bring more equity and transparency to the evaluation of research content, giving systematically excluded researchers better ways to find, train, and contribute to peer review. In her role, she is responsible for partnership and community building, fundraising, and supervising the development of open infrastructure and programs. Other links: https://info.africarxiv.org/ https://zenodo.org/record/6773615#.Yzn4alLMI-Q https://twitter.com/prereview_ https://elifesciences.org/labs/57d6b284/prereview-a-new-resource-for-the-collaborative-review-of-preprints https://onlinelibrary.wiley.com/doi/abs/10.1002/leap.1472 This episode was produced & edited by Jonny Coates. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod, Instagram @Motion_Pod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
44:09
November 02, 2022
Colliding cells; how cell shape affects collision outcomes with Pedrom Zadeh
Colliding cells; how cell shape affects collision outcomes with Pedrom Zadeh
This week we discuss modeling cell-cell collisions with Pedrom Zadeh, a 4th year PhD student at Johns Hopkins University. We learn how to distill basic biology into models and just how important and useful modeling can be as a tool. Read the full preprint -> https://www.biorxiv.org/content/10.1101/2022.05.13.491710v1.full Twitter thread on the preprint -> https://twitter.com/diffusiveblob/status/1526247248241246208?s=20&t=DGdP1wWJYW6wVsBFCeQp1w Other links: 3 blue 1 brown: https://www.youtube.com/c/3blue1brown Atomic Habbits: https://www.amazon.co.uk/Atomic-Habits-Proven-Build-Break/dp/B07J1XQSNK/ref=sr_1_1?adgrpid=130289978361&gclid=Cj0KCQjwj7CZBhDHARIsAPPWv3flGGVJehb4MWwgynAUZMCcrmn0OUt1J3RahhuXQ-y8HHwUb2ULqPMaArOKEALw_wcB&hvadid=542921826939&hvdev=c&hvlocphy=9050361&hvnetw=g&hvqmt=e&hvrand=1668537604868110719&hvtargid=kwd-1463848202564&hydadcr=24400_1816039&keywords=atomic+habits&qid=1663873098&s=books&sr=1-1 This episode was produced by Emma Wilson & Jonny Coates and edited by Camila Valenzuela. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
50:54
October 19, 2022
Divide and Conquer: Cytoplasmic Divisions Without Nuclei
Divide and Conquer: Cytoplasmic Divisions Without Nuclei
This week we discuss how cells can divide without nuclei and why this happens with Anand Bakshi, Fabio Echegaray Iturra (@fabioechegaray) & Mustafa G. Aydogan @AydoganLab. We also highlight Drosophila as an amazing model system that just keeps on giving and speak about the importance of preprints in collaboration and  grant applications. We also discuss the limitations of preprints and the fluidity of science.  Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.06.15.496343v1.full Other links: https://www.theguardian.com/science/2017/oct/07/fruit-fly-fascination-nobel-prizes-genetics https://aydoganlab.com/ This episode was produced by Emma Wilson and edited by Jonny Coates. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
54:12
October 05, 2022
Mitochondrial DNA Sequencing and Diversity
Mitochondrial DNA Sequencing and Diversity
This week we discuss mitochondrial DNA and its importance in aging with Amy Vandiver (@AmyVandiver2). We also highlight a new method to quickly sequence full length mitochondrial DNA allowing for mitochondrial genome comparisons and the understanding of the diversity between mitochondrial DNA.  As usual we also discuss the process of pre-printing, preLights and how they can generate collaborations. As well as understanding more about the MD PhD group leader route. Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.02.23.480720v2.full This episode was produced by Emma Wilson and edited by Jonny Coates. Use the code “jonny” to get free access to an online course all about preprints: https://courses.karger.com/courses/take/how-to-decide-on-preprints-and-open-access-licence/texts/28775362-introduction If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_). Any additional sound effects used are from https://www.zapsplat.com.
43:60
September 21, 2022
Octopus and the many tentacles of research outputs
Octopus and the many tentacles of research outputs
This week we discuss a different take on sharing scientific findings with Alex Freeman (@alex_freeman), creator of Octopus @science_octopus. Octopus is resetting the incentive structure for research sharing, putting the emphasis on assessing the quality of what people are doing within the lab. Find out more here https://www.jisc.ac.uk/rd/projects/octopus-creating-a-new-primary-research-record-for-science Use the code “jonny” to get free access to an online course all about preprints: https://courses.karger.com/courses/take/how-to-decide-on-preprints-and-open-access-licence/texts/28775362-introduction This episode was produced by Jonny Coates and edited by Camila Valenzuela. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
45:33
September 06, 2022
Metabolic heterogeneity in macrophages
Metabolic heterogeneity in macrophages
This week we discuss macrophage heterogeneity with Graham Heieis (@GrahamHeieis), a Post-doc at the Leiden University Medical Center (@LUMC_Leiden) in the Netherlands. We speak to him about mass cytometry and spectral flow cytometry and their use to investigate heterogeneity of tissue specific macrophages with regards to metabolism. We then have our usual chat about preprints, moving labs from Canada to Scotland as well as a bit of a a whiskey discussion.  Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.05.26.493548v1.full This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_). Any additional sound effects used are from https://www.zapsplat.com.
43:21
August 03, 2022
Paper Retractions and Preprint Withdrawals with Michele Avissar-Whiting
Paper Retractions and Preprint Withdrawals with Michele Avissar-Whiting
We’ve gone full circle!! Join us this week as we talk to Michele Avissar-Whiting (@maw_tweets), one of our first ever guests on this podcast and Editor in Chief of Research Square, as we discuss what happens to a preprint when the downstream publication gets retracted, how the papers can be linked to the preprint and if the preprint should be withdrawn. Michele talks to us about her recent paper which examines exactly this. Read the full article: https://doi.org/10.1371/journal.pone.0267971 Other links: https://scholarlykitchen.sspnet.org/2022/06/07/building-stronger-chains-together-keeping-preprints-connected-to-the-scholarly-record/ Use the code “jonny” to get free access to an online course all about preprints: https://courses.karger.com/courses/take/how-to-decide-on-preprints-and-open-access-licence/texts/28775362-introduction This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_). Any additional sound effects used are from https://www.zapsplat.com.
44:23
July 20, 2022
Ciliopathies, ‘Chlamy’ and Cilia length
Ciliopathies, ‘Chlamy’ and Cilia length
This week we discuss cilia length, ciliopathies and Chlamydomonas reinhardtii (also known as ‘Chlamy’) with Brae Briggs (@BiggeBrae), a graduate student from at Dartmouth (@dartmouth),Geisel School of Medicine (@GeiselMed). We find out about a range of ciliopathies, the main composition of cilia as well as using ‘Chlamy’ as a model to study cilia length. We also discuss the difficulties of moving in the middle of a PhD and pandemic, open science principles including preprints as well as how we try to have healthy work life balance. Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.04.18.488674v1.full This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
39:45
July 06, 2022
Prachee Avasthi on ASAPbio, Arcadia Science and the open science mission on our one year birthday
Prachee Avasthi on ASAPbio, Arcadia Science and the open science mission on our one year birthday
We’re 1 year old today! And to help celebrate our Birthday we have an extra long conversation with the incomparable Prachee Avasthi (@PracheeAC), Associate Professor at Dartmouth, President of ASAPbio and CSO & co-founder of Arcadia Science). We discuss everything from Prachee’s career journey, role in promoting preprints and open science with ASAPbio and how she came to co-found Arcadia Science. Arcadia Science: https://www.arcadiascience.com/ Arcadia Science first open house: https://www.youtube.com/watch?v=_tS7CcutTmM Avasthi lab website: http://www.avasthilab.org/ ASAPbio website: https://asapbio.org/ eLife journal: https://elifesciences.org/ NewPI slack: https://newpislack.wordpress.com/ Setting up a lab guide: https://www.preprints.org/manuscript/202012.0147/v1 Read more about what we have achieved in our first year: https://preprintsinmotion.com/?p=913 This episode was produced by Emma Wilson & Jonny Coates and edited by John Howard & Jonny Coates. If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
01:44:25
June 15, 2022
Can we regenerate the heart?
Can we regenerate the heart?
This week we discuss heart dedifferentiation and regeneration with Avraham Shakked @abingtonSA a final year PhD student, at the Weizmann Institute of Science, @WeizmannScience. We speak about their ingenious mouse model which uses transient and temporarily controlled ERBB2 expression which allows dedifferentiation and redifferentiation of cardiomyocytes. Using this model they examined the difference in RNA, protein and heart function in the redifferentiated the cells with and without heart injury. We also speak about preprints, publishing and alternative careers for scientists. Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.02.22.481415v1.full This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
55:36
June 01, 2022
Episode 24: Baby hearts, inflammation and precarious postdocs
Episode 24: Baby hearts, inflammation and precarious postdocs
This week we discuss placental inflammation and heart development with postdoc Eleanor Jayne Ward and PI Suchita Nadkarni (@SciSuchita) from Queen Mary, University of London. In this preprint, the authors show that during embryonic heart development, neutrophils (innate immune cells) can sometimes cause placental inflammation. This inflammation leads to a loss of barrier function. In turn, this allows maternal monocytes (innate immune cells that develop into macrophages) to migrate into the embryonic heart. These monocytes alter the tissue resident embryonic macrophages and damage cardiac tissue. This cardiac damage continues postnatally. We discuss this and how limiting placental inflammation was enough to promote normal cardiac development. We also talk about the precarity of postdocs and why making research/postdoc a recognised profession would be an important step forward. Read the full preprint on bioRxiv https://www.biorxiv.org/content/10.1101/2022.03.10.482611v1.full Visit the Nadkarni lab website https://www.qmul.ac.uk/whri/people/academic-staff/items/nadkarnisuchita.html Read more about the reasons scientists preprint https://www.biorxiv.org/content/10.1101/833400v1 This episode was hosted by Jonny Coates, produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit the subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
49:39
May 17, 2022
Episode 23: Tanycyting: Characterising a neural stem cell niche in the hypothalamus
Episode 23: Tanycyting: Characterising a neural stem cell niche in the hypothalamus
This week we discuss a population of stem cells called tanycytes which line hypothalamus in the brain with Alex Moore (@alexthemessiah) an Operational Research Analyst in the Civil Service & Kavitha Chinnaiya a Post Doc from the University of Sheffield (@sheffielduni).  Tanycytes are population of cells which line the 3rd ventricle in the hypothalamus, self renew and give rise to neurons and glia within the brain. We speak to them about the key findings of their paper which includes expanding on their roles as stem cells, as well as further characterising them with a variety of markers including NrCAM. To do this they evoked a range of techniques including the use of spheroids and single cell RNA sequencing and we chatted to them about those. We also find out about working in the Civil Service and all the skills that PhD offers that helped with this move from academia. Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.12.15.472761v1.full This episode was hosted by Jonny Coats, produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
55:29
May 04, 2022
Episode 22: Caloric Restriction: The Difference Sex and Age Can Make
Episode 22: Caloric Restriction: The Difference Sex and Age Can Make
CW:// This week's episode touches on some themes revolving around caloric restriction which some listeners may find difficult. This week we speak to Ben Thomas @BenThomasSci, a final year PhD student at the University of Edinburgh @EdinburghUni about the benefits of caloric restriction, the impact in male and female mice as well as the effect of age. We highlight the ingrained sexisim within the biological sciences: often only male mice are used and we discuss how this can impact the results of various studies. In addition, we discuss the Edinburgh Open Research Initiative @edinburgh_open which promotes awareness and training of open research principles and lobby’s for these to become formalized within the University of Edinburgh. We also discuss how incentives in science have led to a potentially flawed system and how his experience as a teacher has helped him in academic science. Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.02.20.481222v1.full Other links: https://www.witworks.co.uk/ https://edopenresearch.com/ This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review (on Apple Podcasts or Spotify). If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
57:18
April 20, 2022
Episode 21: Science in motion: How journalists’ approach using preprints
Episode 21: Science in motion: How journalists’ approach using preprints
This week we discuss how journalists approach using preprints with Alice Fleerackers (@FleerackersA), a PhD student at the Simon Fraser University (@SFU). She tells us how she went behind the scenes and to examine the decision making process of journalists on whether to use preprints or not, how they contextualized the science, and what practices they use to evaluate preprints. We discuss the benefits of preprints and highlight the importance of science communication and our role as scientists to prevent the spread of misinformation. Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.02.03.479041v1.full This episode was produced by Emma Wilson and edited by Jonny Coates and John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then buy us a coffee https://www.buymeacoffee.com/preprints! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
53:28
April 06, 2022
Episode 20: Mini Brains - Organoids as 3D Brain Models
Episode 20: Mini Brains - Organoids as 3D Brain Models
This week we discuss organoids and assembloids as models of neurodegenerative diseases with Sònia Sabaté Soler (@scisonias), a PhD student from the University of Luxembourg (@uni_lu). Find out about how 2D stem cells cultures are differentiated into complex 3D midbrain organoids which contain multiple cell types. We also discuss how microglia can be incorporated into the organoids to generate assembloids, mimicking the human brain more robustly. As always we speak about pre-printing and academic culture. We touch on some of the limitations on academia partially with reference to women in STEM and the potential of permanent post docs. . Read the full preprint: https://www.biorxiv.org/content/10.1101/2022.01.21.477192v1.full This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on buy me a coffee https://www.buymeacoffee.com/preprints. Any contribution is greatly appreciated. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
46:44
March 15, 2022
Episode 19: John Inglis & Richard Sever on the Creation of BioRxiv
Episode 19: John Inglis & Richard Sever on the Creation of BioRxiv
A really exciting special episode this week, as we talk to co-founders of BioRxiv (@biorxivpreprint) and MedRxiv (@medrxivpreprint) Richard Sever (@cshperspectives) & John Inglis (@JohnRInglis). We discuss how they met and started with BioRxiv along with the challenges they faced. We then chat about the considerations when accepting or rejecting preprints, or why certain papers are rejected from BioRxiv (they don’t just accept everything).  We also touch on the impact COVID 19 and the pandemic had on preprints as well as discuss the fraudulent papers and how they don’t tend to be pre-printed. If you’ve ever been concerned about preprints this is a great episode to learn more about how preprint servers work and what the future may hold for BioRxiv from the key people in the field. Other links BioRxiv - https://www.biorxiv.org/ MedRxiv - https://www.medrxiv.org/ Company Biologist - https://www.biologists.com/ preLights - https://prelights.biologists.com/ Cold Spring Harbour Lab Press - https://www.cshlpress.com/ Vixra - https://vixra.org/ This episode was produced by Jonny Coates and Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
01:12:49
March 02, 2022
Episode 18: DNA Recorders
Episode 18: DNA Recorders
This week we discuss DNA recorders with Theresa Loveless (@TheresaLovele12), a Post Doc, at UC Irvine. DNA recorders can turn transient events into stable genomic ones and have been used to investigate cell fates and lineages. Join us as we find out more about how this is achieved and the incredible technology behind it!! We also chat about Theresa’s experience of preprinting and academia, and how it can be improved!! Read the full preprint https://www.biorxiv.org/content/10.1101/2021.11.05.467507v1.full Whole-organism lineage tracing by combinatorial and cumulative genome editing: https://pubmed.ncbi.nlm.nih.gov/27229144/ molecular recordings by directed crispr spacer acquisition https://pubmed.ncbi.nlm.nih.gov/27284167/ Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts https://pubmed.ncbi.nlm.nih.gov/33479121/ Prime Editor: https://www.nature.com/articles/s41434-021-00263-9 This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
46:20
February 16, 2022
Episode 17: On-demand Control of Endogenous Genes
Episode 17: On-demand Control of Endogenous Genes
This week we discuss an amazing new technique developed by Dr Jakub Gemperle (@GemperleJakub), a Marie Curie Postdoctoral Research Fellow at the University of Manchester (@OfficialUoM). This technique uses 3 different inducible systems to allow on-demand control of endogenous genes, including being able to remove genes and then re-express them. A nice all in one package of techniques, great for rescue experiments!! We then also talk about Magnetogenetics where cells (and vesicles) can be moved around via magnets! As always we ask how this person found preprinting and we delve into the wonderful idea of permanent postdocs. Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.12.03.471086v1.full Other links https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001285 First Pig to Human heart transplant https://www.nature.com/articles/d41586-022-00111-9 This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com.
42:50
February 02, 2022
Episode 16: The 7 Preprints of Christmas
Episode 16: The 7 Preprints of Christmas
This week is our Christmas Episode! In this episode the Preprints in Motion team get together and discuss exciting, new preprints with a festive theme. We talk about smart soil, mitochondria DNA in relation to COVID 19, shock absorber stress granules as well as a discussion on nepotistic journals and much more including festive cheer and merriment.   Merry Christmas and a Happy New Year from us at Preprints in Motion. Read the full preprints: https://www.biorxiv.org/content/10.1101/2021.11.19.468202v1 https://www.biorxiv.org/content/10.1101/2021.04.26.441141v1.full https://www.biorxiv.org/content/10.1101/2021.09.26.461876v1.full https://www.biorxiv.org/content/10.1101/2020.07.30.227553v1.full https://www.biorxiv.org/content/10.1101/348508v1.full https://www.biorxiv.org/content/10.1101/2021.02.03.429520v1?rss=1 https://www.biorxiv.org/content/10.1101/2020.02.07.938555v1.full This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
50:51
December 22, 2021
Episode 15 - The Exocyst: Somewhere between science and superstition
Episode 15 - The Exocyst: Somewhere between science and superstition
This week we discuss the exocyst with Dr Hannes Maib @hannes_maib a Post-Doctoral Researcher at the University of Dundee @dundeeuni!! He explains the complexities of the exocyst as well as the exciting biochemistry and binding assays used to understand its formation. In addition Hannes speaks candidly about starting working in a new lab as a Post-Doc, his views of hierarchical journal systems and how preprinting can help ECR take back ownership of their work in a great discussion with our host Dr Jonny Coats. Read the full preprint -> https://www.biorxiv.org/content/10.1101/2021.10.14.464363v1.full Other links -> LINK This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
01:01:12
December 01, 2021
Episode 14: Be the change you want to see: Prefigurative politics in academia
Episode 14: Be the change you want to see: Prefigurative politics in academia
This week we discuss prefigurative politics in academia with Stefano Davide Vianello, a PhD student at @EPFL_en in Switzerland. This is the idea that in order to change how a system works we should act in a way that reflects the change we want to see. In Stefano’s case: preprinting to be the end goal and he has therefore submitted a preprint without any intention of submitting it to a journal. We speak to him about his reasons for this, why he is against academics paying for open access as well as 4 key points on what has to change to make academia more open for everyone, not just the global north. Read Stefano’s preprint: https://www.biorxiv.org/content/10.1101/2020.06.07.138883v3 Read Stefano’s opinion piece: https://commonplace.knowledgefutures.org/pub/vzn21ssv/release/2 This episode was produced by Jonny Coates and Emma Wilson, with editing by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
43:07
November 16, 2021
Episode 13 - Mice in Space: Characterizing Mouse Skeletal Muscles After 35-37 Days of Spaceflight
Episode 13 - Mice in Space: Characterizing Mouse Skeletal Muscles After 35-37 Days of Spaceflight
This week we discuss mice in space and the impact of prolonged space flight and how this can relate to austraunoughts with Jessica L Braun @jess_l_braun a PhD Student at the Brock University @BrockUniversity. Jessica speaks about her work looking at soleus and tibialis anterior muscles of mice which have spent 35-37 days on the international space station comparing Ca2+ uptake and SERCA function. We discuss everything from a mice mission control to cardigan rhythms and the different effects on males and female mice. We also talk about preprints and the increased attention it can bring as well as how to improve public engagement. Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.09.27.462048v1.full This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
36:56
November 03, 2021
Episode 12 - Single Molecule Fingerprinting Reveals Different Amplification Properties of α-synuclein Oligomers
Episode 12 - Single Molecule Fingerprinting Reveals Different Amplification Properties of α-synuclein Oligomers
This week we discuss Parkinson’s Disease and single molecule spectroscopy with Dr Derrick Lau, a PostDoc at the University of New South Wales (@UNSW). Single molecular spectroscopy can be used to track the formation and purification of α-synuclein aggregates, a hallmark of PD, and potentially lead to a tool for early diagnosis of Parkinson’s Disease. We discuss how single molecular spectroscopy is transferable to medium throughput and use bio fluids for early diagnosis of Parkinson Disease but also potentially other neurodegenerative diseases. Finally, we discuss preprints, what it it like to apply for PostDocs in a pandemic as well transitioning from immunology and neuroscience.  Read the full preprint - https://www.biorxiv.org/content/10.1101/2021.08.09.455607v1.full Other links Microbiome in PD- https://www.nature.com/articles/s41531-021-00156-z Immunotherapy in PD - https://pubmed.ncbi.nlm.nih.gov/31978602/ α-synuclein in PD patients biofluides - https://pubmed.ncbi.nlm.nih.gov/32444560/ AttoBright - https://www.nature.com/articles/s41467-019-13617-0 https://www.nature.com/immersive/d41586-021-02563-x/index.html This episode was produced by Emma Wilson and edited by John D Howard . If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
46:38
October 20, 2021
Episode 11 - Laterally Transferred Macrophage Mitochondria Act As A Signalling Source Promoting Cancer Cell Proliferation
Episode 11 - Laterally Transferred Macrophage Mitochondria Act As A Signalling Source Promoting Cancer Cell Proliferation
This week we discussed the transfer of mitochondria from macrophages to cancer cells with Dr Chelsea Kidwill & Joseph Casalin, a Post-Doctoral Research Associate and PhD student at University of Utah (@UUtah) in the school of medicine. We delve into why this transfer occurs, the mechanism of transfer and how this impacts the recipient cells. We also speak to Joseph about his alternative schooling, in addition to our usual chat about the importance of preprints and our ideas for how to improve academia. Read the full preprint https://www.biorxiv.org/content/10.1101/2021.08.10.455713v1 This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
46:51
October 06, 2021
Episode 10 - Paywall The business of Scholarship
Episode 10 - Paywall The business of Scholarship
This week we discuss The Paywall Movie with Professor Jason Schmitt, chair of communication and Media at Clarkson University. We talk about academic publishing, the problems of the current system and more.  In 2018, UK universities spent over £210 million on publication costs (access etc). This could have paid for; 700 ECR fellowships or 6500 postdocs or >8500 technicians or 3,500 PhDs (4yr fees + stipend). Meanwhile, Elsevier had profit margins of 37%. This week we discuss the broken publishing system and Jason’s documentary - The Paywall Movie; the business of scholarship. Watch The Paywall Movie for free -> https://paywallthemovie.com/  Learn more about Plan S - https://www.coalition-s.org/  DORA - https://sfdora.org/ Picture a scientist - Netflix.com Retraction Watch - https://retractionwatch.com/ This episode was produced by Emma Wilson & Jonny Coates and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
45:05
September 22, 2021
Episode 09 - Incorrect Nucleotide Sequences Are Unacceptably Frequent Within Scientific Literature
Episode 09 - Incorrect Nucleotide Sequences Are Unacceptably Frequent Within Scientific Literature
This week we discuss how published nucleotide sequences are not always correct or to be trusted with Yasunori Park and Professor Jennifer A Byrne (@JAByrneSci), a research Assistant and PI at the University of Sydney (@Sydney_uni). We delve into the details of their nifty new text mining tool (Blast and Seek) which highlights papers with incorrect nucleotide sequences. We also discuss the most common mistakes found, the impact of these mistakes, and what we can do as researchers to prevent errors from occurring. We also talk about prepints and Australian Research Council’s recent decision to ban preprints in their grant applications as well as some insight into our very own PhD’s. Read the full preprint https://www.biorxiv.org/content/10.1101/2021.07.29.453321v1?fbclid=IwAR2LibD1DD8q6b5df3vMzgFXpmmA6q1E_UarbyaB0dq55fOaY8mmFvzbe14 Other links Open letter to ARC https://asapbio.org/arc This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
47:42
September 01, 2021
Episode 08 - Identification of ACE2 modifiers by CRISPR screening
Episode 08 - Identification of ACE2 modifiers by CRISPR screening
This week we discuss high throughput CRISPR/Cas9 screening and how these have been adapted to investigate novel treatments for COVID-19 with Emily Sherman a former Post Doc and Brian Emmer (@brianemmer), a new PI at University of Michigan (@UMIntMed) In this episode we cover details on how to conduct a high throughput CRISPR/Cas9 screen, the exciting advances in NextGen sequencing as well as what it's like to set up your own lab while working as a clinician during a pandemic. We also speak to Emily about her transition from academia to industry and our usual discussion about the benefits of preprints. Read the full preprint - https://www.biorxiv.org/content/10.1101/2021.06.10.447768v1.full Brian’s lab homepage (https://emmer.lab.medicine.umich.edu/) https://www.nature.com/articles/nm1267 This episode was produced by Emma Wilson and edited by Jonny Coates and John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
51:57
August 18, 2021
Episode 07 - A Transcriptional Switch Governs Fibroblast Activation in Heart Disease
Episode 07 - A Transcriptional Switch Governs Fibroblast Activation in Heart Disease
This week we discuss BET inhibitors and fibroblast activation with Michael Alexanian @m_alexanian a Postdoctoral researcher at Gladstone Institutes @Gladstoneinst. Michael explains how BET inhibitors have emerged as a potent tool to reversibly interfere with enhancers to promoter signalling. This has been shown to ameliorate heart failure in mouse models and is a highly translatable method of preventing heart failure in humans. We discuss two powerful tools, scRNASeq and scATAC-seq, and how they were used to investigate transcription and epigenetic changes of activated fibroblasts. We then discuss the impact of downstream targets and the impact on drug discovery and the limitation of BET inhibitors. Like every week we also highlight the benefits of preprinting, and increasing the accessibility of data within them to scientists around the world. Read the full preprint - https://www.biorxiv.org/content/10.1101/2020.07.21.214874v1.full Other links https://www.nature.com/articles/s41586-021-03674-1 This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
36:27
August 04, 2021
Episode 06 - A Pretty Fly DNA Extraction Method
Episode 06 - A Pretty Fly DNA Extraction Method
This week we discuss how to non-destructively extract and sequence DNA from historical mosquito and tsetse fly samples from the Natural History Museum’s collection. We discover a new method for doing just that with Dr Petra Korlevic (@petrathepostdoc), a Post-doctoral researcher at the EMBL-EBI (@emblebi)/Sanger Institute (@sangerinstitute), and Dr Erica McAlister (@flygirlNHM), Senior Curator of Diptera at the Natural History Museum (@NHM_London). Erica and Petra explain how this method can be used to open up museum collections to molecular researchers in order to answer questions around subjects such as the rise of insecticide resistance amongst these disease vector insects, and the diet, behaviour and ecology of key pollinator species during the rise of global warming or changes in farming practice. We talk about the benefits of preprinting, and how digitising museum collections and developing molecular methods such as this, is increasing the accessibility of data on the specimens within them to scientists around the world. Read the full preprint https://www.biorxiv.org/content/10.1101/2021.06.28.450148v1.full Other links https://www.nhm.ac.uk/our-science/collections/entomology-collections.html https://www.nhm.ac.uk/our-science/departments-and-staff/life-sciences/insects.html https://www.nhm.ac.uk/our-science/our-work/digital-collections/digital-collections-programme.html https://www.liverpoolmuseums.org.uk/insect-collections This episode was produced by John D Howard & Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
57:07
July 20, 2021
Episode 05 - Pros and Cons of Preprints
Episode 05 - Pros and Cons of Preprints
It's all-change at Preprints in Motion this week! Host Jonny Coates takes on the role of guest, while Producer Emma Wilson and Editor John D Howard step in front of the mic for a change and co-host, to bring you a background discussion on the history, and pros and cons of Preprints. Analysis of changes between preprints and their published versions - https://bit.ly/2ZEY5X3 Role of preprints in the COVID-19 pandemic - https://bit.ly/3duUdyc Previous podcast episode on Research Square - https://open.spotify.com/episode/7710Egc44SmA16npXczGrV?si=bDfM9HU8Q3qHn-s1Prb3fQ&dl_branch=1 (Some) preprint servers: bioRxiv  medRxiv OSF preprints ResearchSquare Authorea  Preprints.org metaRxiv  F1000 Research  Preprint review services: Review Commons - https://www.reviewcommons.org/ This episode was produced by Emma Wilson and Jonny Coates and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. If you love what we are trying to do then support us on Patreon https://www.patreon.com/preprintsinmotion where tiers start at as little as £1 a month! For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
01:14:01
July 13, 2021
Episode 04 - How Close Are We to Limb Regeneration?
Episode 04 - How Close Are We to Limb Regeneration?
This week we focus on limb regeneration in amphibians and ask how far away are we from mammalian regeneration? Maybe not as far as we think. We join Dr Can Aztekin @CanAztekin, a recent PhD graduate from Gurdon Institute @GurdonInstitute and current PI in EPFL, Switzerland @EPFL_en. We discuss regeneration in general and a novel tool to investigate different factors involved with regeneration. We also ask him the important questions such as how is it to work with a Nobel laureate? How was it to transition from PhD student to PI and why did he preprint? Read the full preprint https://www.biorxiv.org/content/10.1101/2020.06.01.127654v1 and now published in https://bit.ly/3hkzPmF Other Links EPFL Life science Eearly independent Research Scholar https://www.epfl.ch/schools/sv/school-of-life-sciences-independent-research-scholar Accompanying preLight - https://bit.ly/3AvRqQ1 Disclaimer - During the recording of this episode we had some technical issues so we apologise for the reduced audio quality in some places. This episode was produced by Emma Wilson and edited by John Howard . If you enjoyed this show then hit that subscribe button and leave a review. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates, Emma @ELWilson92, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
41:27
July 06, 2021
Episode 03 - Research Square EiC, Michele Avissar-Whiting
Episode 03 - Research Square EiC, Michele Avissar-Whiting
This week it’s something a little different! We chat with Dr Michele Avissar-Whiting (@maw_tweets) Editor in Chief of Research Square. Research Square is a Preprint platform which aims to make research communication publishing quicker, easier and fairer. We speak about their editing and reviewing process, open access journals as well as general Preprint chat! Other links Michele’s scholarly kitchen article - https://scholarlykitchen.sspnet.org/2021/06/02/guest-post-the-10000-watt-bulb-how-preprints-shine-a-light-on-misconduct/ Research Square webpage - https://www.researchsquare.com Viral Visualizations: How Coronavirus Skeptics Use Orthodox Data Practices to Promote Unorthodox Science Online http://vis.mit.edu/pubs/viral-visualizations.pdf Opinion: The Rise of Preprints Is No Cause for Alarm https://www.the-scientist.com/news-opinion/opinion-the-rise-of-preprints-is-no-cause-for-alarm-68667 This episode was produced by Jonny Coates & Emma Wilson and edited by John Howard. If you enjoyed this show then hit that subscribe button and leave a review. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com where you will also find full transcripts of every episode. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates91, Emma @EmmaWil72848527, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
52:27
June 22, 2021
Episode 02 - Meta-Research Citation needed? Wikipedia and the COVID-19 pandemic
Episode 02 - Meta-Research Citation needed? Wikipedia and the COVID-19 pandemic
Join us as we learn why referencing Wikipedia might not be such a bad idea. We speak to Omer Benjakob @omerbenj, Jonathan Sobel @JonathanSobel1 & Rona Aviram @rona_av who have been investigating the scientific backbone of Wikipedia pages and how referencing on Wikipedia has changed over the COVID-19 pandemic. We discuss how Wikipedia manages to reliably keep up to date with a constantly evolving topic, could this be applied to a social media format to prevent disinformation and could Wikipedia be a great way to engage the general population in science? Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.03.01.433379v2 Other link: Wikipedia is not a newspaper Wikipedia bans The Daily Mail  This episode was produced by Emma Wilson and edited by John D Howard. If you enjoyed this show then hit that subscribe button and leave a review. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates91, Emma @EmmaWil72848527, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
58:33
June 16, 2021
Episode 01 - How to build a microscope out of LEGO
Episode 01 - How to build a microscope out of LEGO
This week join our host Jonny coates as he speaks with Dr Bart Vos, a research associate at the Munster University, as he reveals just how much he likes microscopes. Together they discuss how to build a high resolution LEGO microscope and how these can be used as useful teaching tools for kids and adults alike. They then delve in the world of academic science, the pros, the cons and why we should preprint! Read the full preprint: https://www.biorxiv.org/content/10.1101/2021.04.11.439311v1 Other links: https://en.wikipedia.org/wiki/Micrographia https://en.wikipedia.org/wiki/Antonie_van_Leeuwenhoek https://igem.org/Main_Page This episode was produced by Emma Wilson and edited by John Howard. If you enjoyed this show then hit that subscribe button and leave a review. For the latest podcast news and updates follow us on Twitter @MotionPod or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates91, Emma @EmmaWil72848527, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
39:29
June 15, 2021
The trailer
The trailer
Preprints in Motion is a shiny podcast diving into the fast paced world of preprinted science. Preprints have accelerated the speed at which scientific findings are shared and have helped to move academia towards a more equitable place. Join immunologist and open-science advocate Dr Jonny Coates as he talks to the early career researchers behind some of freshest preprints and learn more about their experience in academia. Each episode discusses their recent science, career journey and their thoughts on science, academic life and much more. Preprints in Motion brings you freshly squeezed science from the biggest experts all within your commute. So, plug-in, sit back and join us as we dive into the fast-paced world of preprints. Episodes will release twice a month – on the 1st and 3rd Wednesday Look out for our special episodes where we discuss the problems (and solutions) in academia with those leading the change Subscribe, rate, review and tell all of your friends!  For the latest podcast news and updates follow us on Twitter @MotionPod, Insta (Motion_Pod) or visit our website; www.preprintsinmotion.com. Produced by JEmJ Productions (find us on Twitter: Jonny @JACoates Emma @EmmaWil72848527, John @JohnDHoward8) and generously supported by ASAPbio (https://asapbio.org | @asapbio_).
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May 04, 2021