
State of Medtech
By State of Medtech


294. From ICU Monitors to AI Twins: How Retia Is Advancing Hemodynamic Monitoring With AI
Episode breakdown:
00:00 – Welcome to the State of Medtech Podcast
00:28 – Introducing Marc Zemel, CEO of Retia Medical
01:05 – Marc Zemel’s Background and Journey to Medtech
02:09 – The Problem Retia Set Out to Solve
02:59 – From Concept to Commercialization: Retia's Path to FDA & Medtronic Partnership
03:44 – Retia’s Primary Use Case: High-Risk Surgeries & ICU
05:00 – Why Accurate Hemodynamic Monitoring Saves Lives
06:43 – AI, Plug-and-Play Design, and Clinician Usability
08:01 – Reducing Clinician Friction with Seamless Integration
09:45 – Alarm Fatigue in the ICU and Retia’s Visual-First Approach
10:55 – Why Retia Is Transitioning to Software as a Medical Device (SaMD)
13:00 – Breaking the Razor Blade Model in Medtech
14:43 – Inside Argos Infinity: Hospital-Wide Remote Monitoring in Action
16:23 – The Future of Clinical Intelligence Platforms
18:03 – Moving Beyond Screens: Retia’s Digital Health Vision
20:37 – Retia’s SaMD Business Model: From Pilot to Platform
22:00 – Acute Kidney Injury and the Economics of Prevention
24:05 – Recurring Revenue and the Power of Per-Bed Pricing
26:00 – Why You Can’t Monitor What You Don’t Measure
27:28 – Retia’s Work with Johns Hopkins: AI and Predictive Outcomes
28:53 – The Growing Role of Cybersecurity in SaMD
30:45 – The SaaS Advantage: Push Updates, Lower COGS, Higher Margins
32:00 – The Rise of the Medtech Algorithm Economy
33:44 – Will Big Tech (Apple?) Enter Medtech Through Acquisitions?
35:00 – iOS vs Android: Who Will Build the Medtech Ecosystem?
36:42 – Strategic Acquirers: Who Might Buy Retia?
38:47 – Closing Thoughts: Building a Physiologic Twin for Critical Care
40:22 – Outro: Where to Learn More About Retia Medical
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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293. Craig Gaffin on Scaling Innovation and ASC Strategy at Smith+Nephew
Episode breakdown:00:00 – Intro: Why ASCs Are Reshaping Medtech02:48 – Smith+Nephew’s Outpatient Playbook with Craig Gaffin06:00 – Why the Future Is Subscription-Based Devices10:31 – What Makes the Cori Robot Different15:22 – Capital Efficiency in Modern Medtech19:10 – Competing with Intuitive Surgical’s Platform Model24:44 – Craig on “Wi-Fi Money” and Recurring Revenue28:02 – How Smith+Nephew Uses Data to Win in ASCs32:17 – Building a Medtech Brand That VCs Respect35:48 – Innovating Without Burning Cash39:20 – Scaling Sales Without a Traditional Sales Force43:55 – Lessons from Medtech Turnarounds47:30 – Why Smith+Nephew Believes in Cori’s Potential51:40 – Private Equity, Growth, and Strategic Control55:29 – The Future of Robotics, Data, and Surgical Simplicity1:00:18 – Craig’s Advice for Medtech Founders1:03:45 – Final Thoughts: The Blueprint for a New Medtech EraShowpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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292. June in Medtech: $700M in Deals, Medtronic’s Strategic Exit & LSI Highlights
Episode breakdown:
00:00 – What June’s headlines missed
01:44 – Why Medtronic exited another business unit
05:02 – The quiet strategy behind “focus”
08:20 – $700M in deal volume: Who’s buying, who’s scaling
09:56 – LSI 2024: What we learned on the ground
13:33 – GTM strategy shifts in diagnostics and devices
15:41 – Private equity’s next move in medtech
18:23 – Boston Scientific’s bet and others to watch
20:10 – Key signals investors are paying attention to
22:50 – Where AI is winning—beyond the hype
26:17 – Medtech’s Q3 setup: what matters next
**Learn more about LSI’s market intel platform and amazing investor summits at LS-Intel.com**Are you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to [GrowMyMedtech.com](http://GrowMyMedtech.com) to book time for a free analysis. Subscribe to our Youtube Channelhttps://www.youtube.com/channel/UCGpL_rGt1LQJwinMq_K7gfgSubscribe to our LinkedIn Newsletterhttps://www.linkedin.com/newsletters/the-state-of-medtech-6863578381842288641/Follow The State of MedTech onLinkedIn https://www.linkedin.com/company/thestateofmedtechInstagram https://www.instagram.com/stateofmedtech/TikTok https://www.tiktok.com/@stateofmedtechX https://twitter.com/StateofMedTechFacebook https://www.facebook.com/stateofmedtech/Follow Omar M. Khateeb onLinkedIn https://www.linkedin.com/in/okhateeb/Instagram https://www.instagram.com/omar.m.khateeb/TikTok https://www.tiktok.com/@omarkhateebofficialX https://twitter.com/OmarMKhateebFacebook https://www.facebook.com/OmarMKhateeb/#medicadevices #medicalsales #medtech #medicalsalesrep #pharmasales #medicaldevice

291. How Mako Became Medtech’s Most Ethical Robot, and Crushed the Shorts
Episode breakdown:
00:00 – Why Ronny Abovitz has better mics than podcasters
01:45 – From MAKO Surgical to Magic Leap: Rony's medtech journey
03:00 – Growing up in Cleveland and why he built MAKO near home
06:00 – The talent stack: engineer, cartoonist, D1 javelin thrower, DJ
14:16 – The cartoon that nearly got him expelled
18:16 – Building MAKO Surgical from a backroom lab
23:16 – How he met Chris Dewey & closed his first big round
30:16 – 9/11 almost killed the company—and how he saved it
34:16 – Mako’s ethical moonshot: the “Mom Rule”
42:05 – What Striker saw in MAKO that J&J missed
52:05 – His partnership with Maurice Ferré and the “talking stick”
58:05 – Going public in 2008 the week after his father died
1:06:05 – How work-life “imbalance” makes legendary founders
1:12:05 – What really happened with Magic Leap’s famous whale
1:16:05 – Rony’s message to founders: “Do what is right”
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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290. Tech’s Answer to Medtech’s Feedback Problem: A Conversation with Fanvoice Founder Sasi Parthasarathy
Episode breakdown:
00:00 – The Hidden Problem in Medtech Feedback
02:16 – From Bing + Netflix to Medtech: Sasi’s Journey
04:17 – The Missing Link in Voice of Customer
08:01 – How Fanvoice Works for Busy Surgeons + Reps
10:17 – Sales as a Strategic Feedback Channel
14:29 – Small Sample, Big Signals: AI Pattern Recognition
16:40 – Sentiment Analysis = Real-Time Product Intelligence
20:22 – Avoiding Slow Burn Failures Through Fast Feedback
26:06 – Consumer-Grade UX Expectations Are Here
28:48 – The Worst Feedback System in Hospitals Today
31:56 – Event-Based Feedback for Early-Stage Startups
34:14 – Automating CRM Insights from the Field
38:19 – From Bookkeeping to Strategy: What PMs Should Really Do
41:06 – Final Thoughts + CTA
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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289. Jelani Abdus-Salaam on AI Agents, HIPAA Compliance & the Rise of Autonomous Healthcare
Episode breakdown:
00:00 – Why AI agents are misunderstood—and underused in healthcare
02:47 – What separates automation, AI, and agents
06:19 – Which industries are deploying AI agents best
08:15 – Overestimating AI: what it *can’t* do yet
10:06 – The wildest use case Jelani’s built: full browser automation
12:56 – AI avatars + loneliness + aging populations = a new medtech opportunity
16:44 – HIPAA-compliant SMS agents for healthcare companies
19:32 – How AI agents triage, qualify, and hand off leads to sales
23:23 – Why prompting is the new programming language
28:13 – Can agents activate field reps based on LinkedIn engagement?
31:02 – AI agentic systems for R&D and clinical education
34:02 – How to identify *where* to deploy your first agent
37:42 – The AI hospital in China: 42 agents, 10K patients diagnosed
38:54 – Why every medtech company will need a simulation department
41:51 – AI agents as education tools for sales and clinical training
46:08 – Where to start: building your AI strategy the right way
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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288. How Pristine Surgical Is Disrupting Endoscopy with Single Use + Subscription Models
Episode breakdown:
00:00 – What’s Wrong with Traditional Endoscopy
03:19 – Bryan’s Path: Law, VC, MIT Startups → Medtech CEO
07:50 – Why Endoscopy Is Ripe for Disruption
11:10 – Breaking Down the Endoscopy Market TAM
13:48 – Starting with Sports Med: Why That Matters
16:30 – Why Pristine Is Betting Big on ASCs
18:33 – The $100K Problem Hospitals Don’t Talk About
19:27 – Real Barriers to Adoption (And How They’re Overcoming Them)
24:34 – Scopes by Subscription: The Medtech Business Model Shift
32:24 – A First Look at the Summit Scope
34:17 – Can Consumer Tech Meet Surgical Standards?
37:19 – Supply Chain Strategy + Tariff Risk
39:25 – What a Cloud-Connected OR Hub Actually Does
44:02 – Flexible Endoscopy and a $56B Market Opportunity
48:26 – Hardware Roadmap: Laparoscopy and Lighting Breakthroughs
50:45 – Business Model Innovation vs. Tech Leadership
53:19 – Where to Find Pristine Surgical in 2025
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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287. How Laura Francis Took SI-BONE Public, Scaled a Category, and Hit Profitability
Episode breakdown:
00:00 – From Chicago Roots to Stanford MBA: Laura’s Unlikely Path
03:19 – Why SI-BONE Was Her First Medtech Role
06:55 – Sabbatical, Reflection, and Finding Purpose in Patient Impact
09:13 – What It Took to Become CEO After Being CFO
11:35 – Leading SI-BONE Through Its IPO
14:43 – The Reimbursement Playbook Behind Their Success
16:41 – Defending a Category Against Fast Followers
19:22 – Why SI-BONE Invested in Risky RCTs (and Won)
22:35 – Building the Data Company: Over 160 Peer-Reviewed Studies
26:17 – Crossing Into Profitability in 2024
32:14 – What’s Next: Breakthrough Devices and New Market Expansions
37:30 – Why SI-BONE Expanded Into Pain Management
43:32 – Managing Surgeons’ Reactions and Staying Mission-Aligned
47:04 – The Leadership Myth That Laura Doesn’t Believe In
51:39 – Real Advice for Female Leaders in Medtech
55:22 – You Can Have It All—But Not All At Once
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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286. Spine: Why Proprio Thinks Surgical Navigation Needs Change — Gabriel Jones on the Future of AI in Spine
Episode breakdown:
00:00 – Why Spine Still Struggles with Innovation
03:41 – Gabriel’s Journey: From Farmhouse Birth to Gates Think Tank
06:48 – What Working With Bill Gates Taught Him About Scale
09:31 – The Problem with Surgical Visibility (And Proprio’s Fix)
13:27 – How Proprio’s Tech Differs from AR, Navigation, and Robotics
16:18 – Real-Time Guidance Without Fiducials
23:18 – Proprio’s Beachhead Market: Spine and Beyond
26:06 – “AI-Complete” in Surgery: What That Actually Means
30:57 – Where Proprio Shines Most in Spine
30:03 – Redefining Surgical Training with Surgeon’s Eye View
40:07 – Why Open Platform Partnerships Will Win
44:42 – Microsoft, Unity & the Future of AI Surgery Platforms
47:49 – What’s Next for Proprio in 2025
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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285. TechMed vs. Medtech: How AI and Data Are Redefining the Industry
Episode breakdown:
00:00 – Intro
03:11 – What is TechMed?
06:00 – Building from data first
15:43 – Why AI adoption in healthcare lags
22:01 – What makes a dataset proprietary
28:11 – Why traditional sales and marketing fail
46:33 – Why VC is struggling—and how TechMed fits
55:18 – The rise of wearables and implants
1:02:39 – What company will be the next Intuitive Surgical?
1:11:55 – How TechMed can attract elite talent
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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284. AI in Fertility: Illumicell’s Bold Bet on Sperm, Longevity & Preventative Health
Episode breakdown:
00:00 – Declining Birth Rates and the Rise of Fertility Tech
01:08 – Founding Illumicell: Oil, Rocket Science & AI Meet Reproduction
03:20 – From Azerbaijan to McKinsey: Jeyla’s Path to Medtech
06:42 – Fertility Deserts in the U.S. and the Accessibility Gap
10:09 – The Real Cost and Toll of IVF on Women
12:48 – Sperm Health as a Predictor of Longevity and Disease
15:47 – Funny & Wild Founding Stories: Market Research in Clinics
21:42 – Illumicell’s Proprietary Imaging and 3D Autofocus
26:22 – The Fertility Tech Business Model: Cash Pay and B2B Focus
32:41 – Strategic Partnerships and Platform Vision
34:50 – Beyond Fertility: Building the Fluid Diagnostics Portfolio
39:25 – From Data to Deals: Insights, DTC, and Biotech Opportunities
42:31 – Clinical Advisors, Harvard Lab Installs & What’s Next for Illumicell
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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283. Avoiding FDA Cybersecurity Rejections: A Medtech Playbook with Blue Goat Cyber
Episode breakdown:
00:00 – Why Cybersecurity is a New FDA Blocker
02:50 – Meet Blue Goat Cyber: Medtech-Only Cybersecurity
04:18 – FDA’s 2023 Final Guidance on Cybersecurity
07:00 – 68% of Devices Are Network Connected (Here’s the Risk)
09:45 – Why Retrofitting Security Fails
13:30 – FDA Risk Management: ISO 14971 vs TIR5717:10 – Secure Software Dev: IEC 62304 & Who Actually Follows It
20:08 – Is ISO 27001 Enough? What the FDA Actually Wants
25:53 – Most Common Deficiency: Insecure Design
30:30 – Blue Goat’s 5-Phase Submission Strategy
36:30 – Hidden Costs of Submitting Late (Cyber ROI)
40:00 – When to Engage Cyber Experts (and What Happens if You Don’t)
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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282. This Month in Medtech: Medtronic spins out diabetes, ResMed’s quiet acquisition acquires, Boston Sci ends heart valve business plus $425M in deals
Episode breakdown:
00:00 – Intro: Is Medtech Having a Moment?
01:30 – Macro Trends: May Outperformed April
03:10 – Medtronic Spins Off Diabetes Division: Why It Matters
06:00 – AI Scams in Tech vs Guardrails in Healthcare
09:15 – Public Market Confidence: Strong Q1 Earnings Recap
12:30 – Intuitive Surgical CEO Transition & What It Signals
14:55 – ResMed’s Long Play: Sleep OS & Apple Vision Pro Strap
18:45 – VirtuOx Acquisition & Diagnosis-as-a-Service
20:53 – Wearables, HRV, and Sleep Tracking Ecosystem
25:45 – Consolidation vs. Independence: Should Inari Have Been Acquired?
28:10 – Boston Sci Exits Heart Valves: Why It’s a Signal
30:25 – Profound Medical & Histosonics: The Real Disruptors in Urology
34:10 – Deals & Dollars: 13 Funding Announcements Breakdown
39:25 – ClearPoint Neuro’s $110M Raise & Brain Surgery Playbook
43:50 – Cranius Therapeutics: Drug Delivery Beyond the Blood-Brain Barrier
46:00 – Salvia Bioelectronics: Owning the Migraine Category
49:00 – Neuromod Deep Dive: Market Share & Emerging Players
52:10 – SetPoint Medical & the Rise of Electroceuticals
56:00 – Outpatient Optimization & Verticalized Care Pathways
58:10 – Final Thoughts & LSI Asia Summit Preview
Learn more about LSI’s market intel platform and amazing investor summits at LS-Intel.com
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281. Urology How Profound Medical is Disrupting Prostate Surgery with AI & MRI-Guided Robotics
Episode breakdown:
00:00 – How Arun Menawat Is Challenging the MedTech Status Quo
01:32 – From Novadaq to Profound: Building a 3rd Medical Device Company
03:19 – What Tulsa Pro Actually Does (Explained Simply)
06:52 – How Engineering Principles Shape Arun’s Leadership Philosophy
10:14 – Why He Took the CEO Role 6 Weeks After Exiting Novadaq
13:23 – Prostate Anatomy & Why Standard Treatment Damages Quality of Life
15:51 – How Tulsa Pro Uses MRI + Sound to Kill Tissue Without Incisions
19:38 – Real AI in Surgery: MRI-Autonomous Targeting + Robotic Execution
22:34 – Treating the Whole Gland Without Losing Function
24:57 – How Tulsa Compares to Procept’s Hydro Robot (Aqua Ablation)
27:22 – PSA Risk Thresholds & Why MRI Lets You See Hidden Cancer
30:42 – Why ASCs Are Perfect for Tulsa Pro (Reimbursement Now Live)
33:41 – Arun’s Personal Experience as a Tulsa Pro Patient
37:56 – The CAPTN Study: Level 1 Data vs. Intuitive’s Flagship Surgery
41:45 – What This Means for the Future of Prostate Cancer Treatment
43:16 – The Real Adoption Barrier: Hospitals Don’t Spend Without Reimbursement
45:41 – The 2026 Playbook: Sales Team, Pipeline, and Hockey Stick Growth
46:27 – Other Indications: Pancreatic, Liver, Uterine, Fibroid Trials Underway
48:45 – Staying Focused on Urology While Building for the Future
51:08 – Why Intuitive Surgical & Procept Are Real But Beatable Competition
54:40 – Book Recommendation: Measure What Matters by John Doerr
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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280. The Future of Stroke Diagnosis: Robert Hamilton on NeuraSignal’s Mission to End Missed Strokes
Episode breakdown:
00:00 – Intro: AI Meets Stroke Care
01:00 – Robert’s Journey from UCLA to Neurocritical Units
02:10 – Why Stroke is 30 Years Behind Cardiology
03:36 – Why Only 5–8% of Hospitals Use TCD
04:15 – How Stroke is Diagnosed Today (and Why It Fails)
05:28 – 80% of Strokes in Community Hospitals Have No Known Cause
07:16 – The Role of PFOs and Why TTE Misses Most of Them
10:15 – How Bubbles Reveal Stroke Risk Through the Brain
12:31 – How NeuraSignal’s Platform Automates Diagnosis
14:30 – Why 30% of Stroke Patients Miss the Treatment Window
15:47 – Robotics + AI + Ultrasound = Real-Time Stroke Insights
18:58 – Why Accessing the Skull Is So Complex (and How They Solved It)
20:37 – Weekly Cases Where NeuraSignal Prevented a Second Stroke
23:42 – What Happens After a PFO Is Found
24:53 – PFOs & Migraines: The Unlikely Connection
26:12 – The Bigger Vision: LVO, Cardiac OR, and Pre-Hospital Stroke Detection
29:01 – FDA Strategy: AI, Digital Biomarkers, and Future Indications
30:55 – Existing CPT Reimbursement Pathway & CMS Status
32:32 – Clinical Trials: Bubble, CommonSpirit, HCA & AHA Guidelines
34:39 – Stroke Care in 2030: What It Could Look Like with NeuraSignal
36:14 – Where to Meet NeuraSignal at Fall Conferences
37:40 – Clinical Adoption: From Academic to Community Hospitals
39:05 – How They Fit Seamlessly Into Stroke Workflows
40:50 – Making AI MedTech Accessible, Not Just Academic
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279. Ray Cohen on Building & Selling Billion-Dollar MedTech Startups Without Bankers
Episode breakdown:
00:00 – Intro: Ray Cohen’s MedTech Resume
02:21 – 44 Years, 0 BigCo Jobs: Ray’s Founding Philosophy
05:04 – How He Closed a $600M Deal Without an Investment Banker
08:05 – Why Relationships Matter More Than Bankers in M&A
11:19 – When Is the Right Time to Sell a MedTech Company?
13:44 – Why He Took Axonics Public *Before* FDA Approval
15:53 – $111M in Year 1 During COVID — How They Pulled It Off
17:42 – Why Most Commercialization Efforts Fail
19:19 – $230M IPO: How He Built the Case for Kestra’s Public Debut
22:36 – Turning Venture Dollars into a $1.2B Public Company
24:02 – The Founder’s Trap: Pivot or Persevere?
27:57 – How to Work with Strategics Without Giving Away the Deal
29:37 – Loyalty, Teams & Why Integrity Still Wins in MedTech
34:12 – Stop Worrying About Dilution. Raise More Than You Need.
35:43 – The $30M Fight Against Medtronic — And Why They Won
38:23 – The American Dream is Still Alive in MedTech
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278. Market Engineering and Why Startups Fail After Funding with Traction Gap Author Bruce Cleveland
Episode breakdown:
00:00 – Why This Episode Will Save Your Startup
01:25 – From Oracle to C3.ai: Bruce’s Operating + VC Journey
06:08 – What the VC World Doesn’t Tell Founders
10:47 – Why Most Startups Burn Cash After Raising
14:09 – The “Stadium” Metaphor: You Need a Category Before a Sales Team
18:06 – Creating the Enterprise AI Category at C3.ai
23:00 – SEO Hacks: Glossaries, Whitepapers, & Google Snippets
27:50 – Product-Market Fit Is Dead. Think Market-Product Fit
32:54 – Why Most Category Design Efforts Fail
39:30 – Why FDA Approval ≠ Market Readiness in MedTech
41:29 – Bruce’s Visual Traction Gap Map Explained
46:00 – MVP Is a Clock You Start—Too Early & You Lose
50:29 – MedTech Metrics: How ARR Maps to Repeatability
54:28 – How to Align Teams Across Phases Using Diagnostics
58:24 – Aligning Adoption Curve with Company Lifecycle
1:02:58 – The 76% Rule: Why Market Leaders Capture All the Value
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277. Inside Intuitive: Gary Guthart on AI, Diagnosis Delays, and Medtech’s Future
Episode breakdown:
00:00 – Why MedTech Still Fails Patients
03:19 – The Diagnosis Delay Crisis: Lung, Heart & Endometriosis
09:31 – Intuitive’s Vision: Redefining Outcomes Through Technology
12:01 – How Intuitive Measures Success: The Quintuple Aim
14:56 – Inside Intuitive’s Innovation & Startup Ecosystem
21:34 – From Mathematician to MedTech CEO: Gary’s Founder Journey
25:50 – Startup Grit: Navigating the AI River in Healthcare
29:16 – Leadership & Culture: What Drives Intuitive’s 97% Retention
32:33 – Mentorship in MedTech: How to Attract the Right Advisors
35:00 – Balancing Stakeholders: Patients, Hospitals, Investors
37:53 – AI in Healthcare: Signal vs. Hype, Pipes vs. Math
41:40 – Omar Khateeb asks how Intuitive Maintains a Culture of Disruption
48:22 – The Pivotal Pivot: From Cardiac to Urology & Global Scale
50:17 – Navigating Turbulent Times: Advice for Founders & VCs
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276. Stroke: Using Histotripsy for Stroke with Dr. Ameer Hassan of Quantanosis
Episode breakdown:
00:00 – Intro: Meet Dr. Ameer Hassan & Quantanosis
01:45 – From Interventional Neurologist to Founder
04:00 – Global Stroke Access Crisis: The Mission Behind Quantosis
10:48 – The State of Mechanical Thrombectomy Innovation
12:58 – Fundraising $3M in One Day: How He Got Started
16:28 – What Is Histotripsy and Why It’s a Game-Changer for Stroke
19:13 – Risks of Current Stroke Devices: Endothelial Damage Explained
21:58 – The Future: Portable, AI-Powered Stroke Care in the Field
24:13 – Stroke Market Trends: U.S. vs Global CAGR
30:16 – Australia’s Hub-and-Spoke Model: Why It Works
32:35 – High-Risk Populations: Stroke and Atherosclerosis in Underserved Areas
35:35 – The Quantosis Device: Design, Use, and Treatment in 45 Seconds
38:30 – Using AI to Locate and Target Clots
39:45 – Breaking Through Bone: The IP That Makes It Work
41:45 – Regulatory Pathway: U.S. First-in-Human Strategy
44:25 – Series A Plans and What’s Next
46:45 – Where to Meet Quantanosis in 2025 (Conferences & Events)
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275. Bulletproof Your Knees: Dr. Alan Reznik on Longevity, Injury Prevention, and Smart Joint Training
Episode breakdown:
00:00 – Intro: Why Knee Health Matters More Than You Think
01:59 – Meet Dr. Alan Reznik: Surgeon, Author, Engineer
04:29 – Anatomy 101: How the Knee Actually Works
09:46 – Why ACL Tears Are So Common (and How to Avoid Them)
13:16 – Cleats, Turf & the Injury Epidemic in Sports
16:36 – The Force Chain: Why Weak Hips Destroy Knees
21:16 – How a Kid Fixed His Shoulder by Training His Hips
23:46 – Squatting & Deadlifting: What’s Too Much Weight?
30:16 – Mobility vs Strength: Which Comes First?
32:46 – Joint Wear, Lubrication & Cartilage 101
38:16 – Reaction: Brian Johnson’s Anti-Aging Knee Workout
41:46 – Eccentric Training Explained (And Why It Works)
44:46 – The Nordic Curl Debate: Great or Dangerous?
48:46 – Why Your Supplements Might Not Be Helping
53:46 – When to Stop Therapy and See a Surgeon
58:46 – What Actually Rebuilds Cartilage?
01:04:46 – How to Know if Your Implant Surgeon Is Any Good
01:09:46 – Final Tips: Dr. Reznik’s “KNEES” Framework
Meet me in NYC this May at MD&M East May 20-22! Get a free expo pass and see my keynote on Wednesday May 21st! Click here and use code OMAR25 https://utm.io/uidBR
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274. This Month in Medtech: Edwards’ Big Move, $200M Robotics Bet & AI Shifts
Episode breakdown:
00:00 – Intro: Why April Was a Pivotal Month for Medtech
01:52 – Supira Medical Raises $120M for pVAD Innovation
05:34 – CMR Surgical’s $200M Robotics Bet
09:12 – Edwards Lifesciences Gets CE Mark for Sapien M3
13:01 – Biolinq’s $100M Needle-Free Glucose Monitor
15:27 – AI + Imaging: Anumana and Conavi Raise Big
18:40 – The Numbers: 3 Fastest-Growing Procedure Segments
21:45 – The APAC Expansion Opportunity for Medtech
24:15 – NAMSA, FDA, and the New Clinical-First Strategy
27:00 – Closing Thoughts: What to Watch Going into May
Meet me in NYC this May at MD&M East May 20-22! Get a free expo pass and see my keynote on Wednesday May 21st! Click here and use code OMAR25 https://utm.io/uidBR
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273. Family Office: How Ivanny Franklin Uses Her NAMSA Experience to Invest
Episode breakdown:
00:00 – Intro: From NAMSA to MedSite Capital
01:52 – Who Is Ivanny Franklin? Her $B Exit Story
03:33 – Why She Started a Medtech Family Office
05:04 – MedSite’s Investment Strategy: SPVs, Syndicates, Direct
07:17 – Where She’s Investing: IVD, Cardiovascular, Health Tech
10:50 – How NAMSA’s Scale Gives Her Market Pattern Recognition
13:40 – Top Red Flags in Pitch Decks (Founders, Listen Up)
16:30 – 510(k) vs PMA: Why Your FDA Path Can Kill a Deal
18:55 – Clinical Trial Design: $1M vs $10M and What Drives It
20:50 – The Most Overlooked Statement in Regulatory Strategy
23:00 – Balancing Legacy with Risk: Family Office Real Talk
26:00 – Syndication as a De-Risking Strategy (Real Examples)
29:00 – How She Decides Between Direct vs Fund Investments
32:00 – Check Sizes, Stages, and How She Allocates
33:45 – Where Family Offices Actually Source Deals
35:45 – How Referrals, Ecosystems, and Events Drive Access
37:30 – Why Medtech Needs a “Family Office Network”
40:00 – The Conferences She Attends Year After Year
43:00 – AI in Medtech: Her Risk View & What She’ll Actually Back
45:00 – What Most Pitch Decks Are Missing (It’s Not What You Think)
48:00 – Why Clinician Feedback Is More Valuable Than Market Reports50:00 – Pre-FDA? You Still Need a Pipeline Strategy52:10 – Outside the Office: Travel, Horses, and E-Bikes53:30 – Final Thoughts: How Founders Win with the Right Support
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272. Pain: Optogenetics, Closed-Loop Pain Tech & AI: Dr. Tim Deer on the Future of Interventional Spine
Episode breakdown:
00:00 – Intro & What’s New in Pain02:00 – Turf Wars Are Over: Surgeons & Pain Docs Collaborating05:00 – Closed Loop for Peripheral Nervous System08:00 – Optogenetics & Viral Vector Therapy for Pain13:00 – New Tech Targets: Parkinson’s, Gait, Sleep Apnea16:00 – Imaging, Biomarkers & Functional MRI in Pain19:00 – Strategic Acquisitions: The Pros & Pitfalls24:00 – Device vs Pharma: The Real Long-Term Win30:00 – AI & Patient Selection: The Future of Tailored Pain Medicine35:00 – Why Physicians Struggle to Organize38:00 – IPOs & M&A Predictions for 202542:00 – How Startups Fail by Raising Too Much47:00 – NANDS, Non-Surgical Back Pain Study Highlights51:00 – Aspen Conference 2025: What to Expect54:00 – Closing: The Word of the Future is “Judgment”
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271. Josh Makower on the FDA & AMA Impact on Medtech Innovation & How to Fix It
Episode breakdown:
00:00 Introduction to Dr. Josh Makower and His Impact on MedTech
02:45 How Innovation Happens in Healthcare and Medical Devices
08:08 Why Reimbursement Reform Is Critical for MedTech Startups
08:49 Breaking Down the Complexities of Reimbursement Systems
12:10 How Medical Coding Affects Patient Access to Innovation
14:53 Challenges in Insurance Coverage and Healthcare Payments
17:58 How Regulatory Changes Influence Medical Innovation
20:48 Why Transparency Matters in Healthcare Reimbursement
24:10 Barriers Slowing Adoption of New Medical Technologies
26:48 Understanding the Economics Behind Healthcare Innovation
30:43 How to Create a Predictable Medical Coding Process
30:53 Overcoming Coverage and Insurance Challenges
32:50 The Role of Government in Healthcare Reimbursement Reform
36:13 Why Transparency Is Key to Driving Medical Innovation
37:58 Why Funding Medicare Is Essential for Better Patient Care
40:50 How to Accelerate Coverage for Breakthrough Technologies
42:30 How Coding, Coverage, and Payment Interact in MedTech
48:32 Rapid Fire: Josh Makower’s Insights and Personal Reflections
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270. Running a Public Company vs Startup with Todd Usen
00:00 Differences Between Startups and Large Strategic Companies
12:05 Building and Leading High-Performing Teams
17:06 Retaining Top Talent in a Competitive Market
21:19 Transitioning from Large Strategic Companies to Startups
26:32 The Importance of Quality Assurance and Regulatory Compliance in Startups
30:55 Hiring Key People and Building a Strong Team
39:15 The Art and Science of Assembling a Board
48:42 Challenges of Fundraising in the MedTech Industry
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269. Jim Alecxih on Tailoring Your Value Prop to the Surgeon
00:00 – Introduction and New Role
04:00 – Innovative Technology in Medical Imaging
08:44 – The Art and Science of Tailoring Value Propositions
18:45 – Understanding Stakeholders and Their Needs
26:38 – Sales Philosophy: Aligning Aspirations with Solutions
38:28 – Navigating Limited Territories in Sales
40:14 – Navigating Career Dynamics in Sales
43:15 – The Importance of Proactive Career Management
46:42 – Criteria for Making Life Decisions
49:42 – Embracing Discomfort for Growth
52:54 – Understanding Market Waves and Problem Solving
55:28 – Building a Compelling Personal Brand
59:53 – Learning from Failure and Personal Development
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268. The Future of Endoluminal Surgery with Dr. Todd Wilson
00:00 Introduction to Robotics and EndoQuest
02:55 The Problem of Traditional Endoscopy
06:13 Efficiency and Learning Curves in Endoscopic Procedures
08:53 Market Potential and Comparisons to Other Technologies
11:53 Overview of the Robotic System and Its Features
21:07 Clinical Trials and FDA Approval
25:12 Future Goals and Market Outlook
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267. Exits: Greg Lucier - Billion Dollar Exits and Why He’s Still On the Hunt to Acquire MedTech Assets to Challenge Strategics
00:00 Introduction to Greg Lucier and His Journey
03:00 Transition from GE to Medical Device Industry
05:49 Lessons Learned at GE
09:07 Embracing Risk and Learning from Failure
11:54 Cultural Adaptation at Invitrogen
14:58 The Evolution of Genomics in Medicine
18:06 Transforming Invitrogen to Life Technologies
21:12 Merging Companies and Creating New Cultures
24:09 Navigating the Financial Crisis and Growth Strategies
27:07 The Sale of Life Technologies
29:59 Taking the Helm at Nuvasive
32:48 Implementing Change and Growth at Nuvasive
43:35 Cultural Transformation and Leadership
46:03 Manufacturing and Globalization Strategies
48:58 Lessons from NuVasive's Growth
52:07 The Future of Spine Surgery
54:54 Navigating Business Ethics in Healthcare
57:05 The Role of People in Business Success
01:00:02 Transitioning to Private Equity and New Ventures
01:03:04 Challenges in the Healthcare Industry
01:07:00 The Future of Corsa Medical
01:09:57 Rapid Fire Questions and Personal Insights
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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266. President’s Club: Stryker Mako Specialist & 3x Prez Club Winner Brandon Hoover
00:00 Introduction to Presidents Club and Rep Prep
02:27 Brandon Hoover's Journey in Medical Sales
04:30 Winning Presidents Club: Strategies and Experiences
06:17 Building Relationships with Surgeons
12:54 Transitioning to Oncology Sales
19:26 Call Preparation and the Importance of Research
20:03 Researching Medical Professionals
22:31 Launching Fulgent Oncology
24:42 Transitioning to SaaS for Medical Sales
26:51 User Experience of RepRep 2.1
32:21 Key Resources for Sales Success
34:29 Lessons from Mentorship and Mistakes
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265. The Mako Surgical Story with Founder Maurice R. Ferré, MD
00:00 Introduction to Dr. Maurice Ferre
02:13 Maurice's Journey to Medicine and Entrepreneurship
10:03 The Evolution of Mako Surgical
15:01 From ZCat to Mako: The Transformation
26:52 The Vision Behind Mako's Technology
32:21 Navigating Challenges and Securing Funding
41:05 The Journey to Mako's IPO
42:01 The Impact of Mako's Acquisition by Stryker
45:39 Building a Sales Pipeline and Surgeon Adoption
49:55 Key Inflection Points in Mako's Growth
54:27 Lessons Learned as a First-Time CEO
01:01:18 The Vision for Insight Tech
Don’t Let Cybersecurity Risks Delay Your Medical Device Premarket Approval. Check out BlueGoatCyber.com
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264. Neuro: Using Brain-Computer Interface to solve motor impairment with Kurt Haggstrom, Chief Commercial Officer at Synchron
00:00 Introduction to Neurotech and Synchron
01:48 Kurt Hagstrom's Journey in MedTech
05:11 Transitioning to Synchron and BCI Innovation
10:01 Understanding the Need for BCI Technology
13:16 Challenges in the BCI Field
18:14 Synchron's Unique Approach to BCI
22:15 Adoption and Implementation of BCI Technology
24:12 Maximizing Visibility in MedTech
26:59 Innovations in Brain-Computer Interfaces
30:31 Understanding the Interventional Neurology Landscape
32:29 Restoring Mobility Through Technology
36:48 The Future of Neurotechnology
41:10 Clinical Trials and Patient Engagement
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263. Changing Surgical Training Culture with Medtronic’s Orleigh Bogle
00:00 Introduction to MedTech and Surgical Training
02:08 Current Landscape of Surgical Training
05:48 The Role of AI in Surgical Training
11:49 Cognitive Training and Visualization Techniques
20:02 Democratizing Surgical Training with Technology
25:47 Feedback and Continuous Improvement in Surgical Practice
31:53 Conclusion and Future of Surgical Training
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262. Hospital Operations: Using AI to Automate Hospital Operations with David Atashroo MD & Matt Heim of Qventus
00:00 Introduction to AI in Healthcare
01:07 Understanding Qventus and Its Unique Solutions
03:29 The Surgeon’s Perspective on AI Integration
06:21 Adoption Challenges in Healthcare Technology
07:27 Finding the Right Audience for Adoption
09:14 The Role of Clinical Champions in Technology Adoption
12:41 Empowering Clinicians Through Technology
14:18 Case Study: Boston Medical Center's Success
17:19 Timeline for Realizing Results
18:18 Common Operational Challenges in Hospitals
20:33 Data Ownership and Model Training in AI
23:52 The Importance of Customer Success in SaaS
26:08 Understanding KLAS Research Scores
28:12 Maximizing Technology Utilization in Hospitals
34:03 Overcoming Barriers to AI Adoption in Healthcare
37:45 The Importance of Sharing Success Stories Among Hospital Executives
41:34 Building a Sustainable Business Model in Healthcare AI
48:00 Hiring the Right Talent for Healthcare Innovation
Spotify
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261.Anesthesia: AI & Robotics for Airway Management with Dimitri Sokolov, CEO of Spiro
00:00 Introduction to MedTech and Robotics
03:07 The Trojan Horse Strategy in Airway Management
06:01 Current Challenges in Intubation Techniques
08:56 Innovations in Intubation Technology
11:59 Regulatory Pathways and Clinical Trials
15:08 Market Potential and Business Strategy
18:04 Future Developments and AI Integration
20:57 Conclusion and Future Outlook
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260.Diagnostics: Detecting Esophageal Precancer with Lishan Aklog, CEO of Lucid Diagnostics
00:00 Introduction to MedTech and Cancer Prevention
03:01 Dr. Lishan Acklog's Journey in Medicine
05:59 The Impact of Cardiac Surgery and Influential Figures
12:07 Transitioning from Surgery to Entrepreneurship
17:59 Founding Lucid Diagnostics and the Focus on Esophageal Cancer
24:04 Understanding Esophageal Cancer and Its Challenges
31:53 Understanding Esophageal Cancer and Its Causes
35:18 The Role of EsoGuard in Early Detection
39:36 Innovative Cell Collection Techniques
46:41 Commercial Strategies for Patient Access
51:44 Reimbursement Challenges and Solutions
57:17 Clinical Performance and Market Potential
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259.Soft Skills in Medicine with Mohammed Teleb MD
00:00 The Importance of Soft Skills in Medicine
06:05 Understanding and Developing Soft Skills
11:47 Listening and Non-Verbal Communication
17:53 Mind-Body Connection and Patient Interaction
23:55 Self-Improvement and Personal Growth
30:03 Building a Supportive Clinical Team
32:20 Building a Supportive Team Culture
39:03 The Importance of Continuous Learning in Medicine
47:30 Integrating AI in Medical Training
58:05 Soft Skills for Clinicians
01:02:14 Future Directions in Medical Conferences and Networking
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258. Ophthalmology: Eyelid Rejuvenation with Patricia Buehler, MD, Founder of Osheru
00:00 Introduction to Ophthalmology and Osheru
02:57 The Evolution of Eyelid Surgery
06:03 Innovations in Blepharoplasty with ZipLyt
09:12 Clinical Insights and Patient Outcomes
11:59 Market Potential and Business Model
15:01 Regulatory Pathway and Future Plans
18:09 Strategic Partnerships and IP Strength
20:56 Conclusion and Future Outlook
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257. Neurotech: Tackling Alzheimer’s through Drug Free Tech with Christian Howell, CEO of Cognito
00:00 Introduction to Alzheimer's and Cognito
05:10 Christian Howell's Journey in MedTech
09:50 Leadership Lessons from Medtronic
15:09 Cognito's Mission and Focus on Alzheimer's
20:00 Innovative Approaches to Alzheimer's Treatment
24:46 Partnerships and Community Engagement
30:00 The Science Behind Cognito's Technology
34:17 The Brain Workout: Understanding Gamma Waves
39:02 The Overture Study: Insights and Results
45:19 Cognito's Business Model: Patient Journey and Revenue
56:11 Future Directions: Beyond Alzheimer's and Platform Technology
Cognito study: https://www.hopestudyforad.com/
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256. Medical Sales Rep to Owning a Medtech Development Company with Jason Scherer, CEO of VitaTek
00:00 From Med Rep to Entrepreneurial Success
10:00 The Birth of VitaTek
20:09 Innovations in Hydrophilic Coating
29:49 Future Trends in MedTech
36:01 Conferences and Networking Opportunities
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255. Neurology: Using Catheter-Based Technology to Interface with the Brain with Jose Morales MD, Founder of Vonova
00:00 Introduction to Interventional Neurology and Vonova
11:44 The Evolution of Functional Neurosurgery
24:41 Vonova's Innovative Approach to Subdural Hematomas
38:16 Future Directions and Regulatory Pathways for Vonova
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254. Revolutionizing Lymphedema Care: The Koya Medical Story with CEO & Founder Andy Doraiswamy
00:00 Introduction to Koya Medical and Lymphedema
05:03 Andy Doraiswamy's Journey and Background
09:59 Understanding Lymphedema and Its Prevalence
14:59 Current Standards of Care for Lymphedema
20:01 Innovations in Lymphedema Treatment: DaySpring Device
25:09 Clinical Studies and Their Impact
29:56 Future Vision for Koya Medical
link to TEAYs study https://www.jvsvenous.org/article/S2213-333X(24)00361-5/fulltext#fig3
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253. Robotics: Distalmotion CEO Greg Roche

252. Family Office: Life Sciences Investor Dr. Juliette Singh

251. Career: How to Accelerate Your Career Growth in Medtech with Henry Peck

250. Cardiac Investing: Investor & Board Chairman Ken Nelson

249. Neuro: A New Low-Profile Intracranial Device Platform with Jesse Christopher, CEO, Longeviti Neuro Solutions
00:00 Exploring the Frontiers of Neurosurgery
03:00 Jesse Christopher's Journey to Longevity Neurosolutions
05:46 Innovating in Neurosurgery: The Birth of Longevity
08:56 The ClearFit Platform: A New Era in Diagnostics
12:04 Transforming Patient Care with Real-Time Imaging
15:09 The Future of Neurosurgery: Collaboration and Innovation
23:50 Understanding Adverse Events in Healthcare
24:50 The Economic Impact of Bedside Ultrasound
25:47 Innovations in Imaging Technology
26:58 Investment Opportunities in Medical Technology
28:12 The Future of Ultrasound in Diagnostics
30:00 Real-Time Imaging and Patient Mobility
32:06 Telehealth and Remote Monitoring Innovations
33:39 Economic Viability and Innovation in Healthcare
34:38 Research and Outcomes in Neurosurgery
39:11 AI and Data Capture in Healthcare
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248.Transformation - How to drive value creation in people, products and go-to-market with Michael Farrington, Chief Growth and Transformation Officer at Corza Medical
00:00 Introduction and Background of Michael Farrington
05:01 Transformative Go-to-Market Strategies at Nuvasive
12:17 The Importance of Focus in Marketing
18:40 The Role of Technology in Marketing
29:43 Building Company Culture and Alignment
34:51 The Importance of Trust in Leadership
41:00 Building a Culture of Trust
46:56 Lessons from Industry Leaders
52:54 Attracting Talent in a Competitive Market
58:50 The Future of Corsa Medical
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247. Physician Entrepreneurship Program Through Dartmouth’s 3D Scholar Program with Dr. Aaron Kaplan & Dr. Emily Zeitler
00:00 Introduction to the 3D Scholars Program
02:29 The 3D Symposium: A Unique Gathering
07:42 Exploring the 3D Scholars Program
15:21 Challenges for Clinicians in Device Development
20:09 The Importance of Regulatory Knowledge
27:30 Curriculum Highlights and Expectations
33:29 Application Process and Diversity in Selection
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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246. President’s Club: SaaS Sales with Justin Jelley
00:00 Introduction to Enterprise Sales Dynamics
01:31 Justin Jelle's Sales Journey
03:34 The Appeal of Showpad
05:42 Traits of Successful Enterprise Salespeople
09:44 Navigating Digital Relationship Building
12:53 Strategies for Maintaining Customer Relationships
14:45 Prospecting Techniques for Initial Relationships
16:49 Leveraging LinkedIn for Sales Intelligence
19:14 Using AI for Sales Preparation
20:51 The New Frontier of Sales Differentiation
25:33 Creating Value in the Buying Experience
31:30 Learning from Sales Experiences
33:32 Transitioning from Large Corporations to Startups
35:04 Continuous Learning in Sales
Showpad has been helping medtech marketers use data and content to empower sellers to grow pipeline. Learn more at Showpad.com/StateofMedtech
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244.Using Robots for Microbial Reduction
00:00 Introduction and Background 08:18 From Rackspace to Xenex 11:24 Entering the MedTech Industry 14:15 Transitioning to CEO 16:21 The Importance of Passion and Mission 20:15 Overcoming Challenges and Changing the Status Quo 29:19 Xenex's FDA Authorization 34:05 Differentiating Factors and Challenges to Adoption 38:22 Xenex's Business Model 43:54 Xenex's Response to the COVID-19 Pandemic
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