Skip to main content
Computationally Yours

Computationally Yours

By Sabah Kadri and Arshi Arora
(n-1) things to explore and discuss about Computational Biology. Join us as we converse about everything computational in the biomedical sciences and beyond. #accessibleScience
Listen on
Where to listen
Apple Podcasts Logo

Apple Podcasts

Breaker Logo

Breaker

Google Podcasts Logo

Google Podcasts

Overcast Logo

Overcast

Pocket Casts Logo

Pocket Casts

RadioPublic Logo

RadioPublic

Spotify Logo

Spotify

Currently playing episode

Episode 4: Clinical Trials for Infectious diseases

Computationally Yours

1x
Episode 18: Flavors of Computational Biology
In this episode, your hosts, Dr. Sabah Kadri and Arshi Arora bring to you united yet diverse sub fields of Computational Biology in the voice of four different scientists, spanning areas of Structural Biology, Systems Biology, Chemistry, Proteomics and Genomics. They cover their background, speciality and what drew them to Computational ability in the first place. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Website: http://computationallyyours.netlify.app/ Follow us on Instagram https://www.instagram.com/computationallyours/ Intro/Outro music: Riatsu (Shadaab Kadri) Thumbnail: Thanks to Zoltan Tasi for sharing their work on Unsplash.
22:45
September 22, 2020
Episode 17: The road ahead in genetics and genomics
In this episode, Dr. Sabah Kadri and Arshi Arora discuss the viewpoints of 6 esteemed scientists from the latest Nature review Genetics paper celebrating 20 years. From population genetics to non-coding genome, from equity to diversity and more, this is a must listen. Paper discussed: https://pubmed.ncbi.nlm.nih.gov/32839576/ Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Website: http://computationallyyours.netlify.app/ Follow us on Instagram here. Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here.
25:46
September 15, 2020
Episode 16: Mendel, the Father of Genetics
In our next “Profiles of Scientific Genius” series, we bring to you the life story of the Father of Modern Genetics, Gregor Johann Mendel (1822-1884). Dr. Sabah Kadri and Arshi Arora talk about his journey from a monk to a scientist, his iconic work on pea plants, Mendel's Laws of inheritance, and lastly a brief note about the  Mendel-Fisher controversy. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Website: http://computationallyyours.netlify.app/ Follow us on Instagram here. Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here.
17:02
September 1, 2020
Episode 15: The Mega Crossover Episode
In this episode, we sat down with hosts of 5 other podcasts on pathology and science: Deeper Levels, People of Pathology, PathPod, ScopeMD, and Dead Men Do Tell Tales for a Mega crossover episode.  We talk about podcasting, what got us started on this journey, what we have learned, and even share a joke. It was fun to share and learn from our fellow podcasters. Other podcasts featured in this episode: Deeper Levels PathPod ScopeMD Dead Men Do Tell Tales People of Pathology Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Website: http://computationallyyours.netlify.app/ Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here.
1:10:00
August 25, 2020
Episode 14: Challenges of COVID testing from the experts who make it happen
In today’s episode, we reached out to four diagnostic experts across the United States to share their experiences in bringing on SARS-CoV-2 testing in their laboratories. We asked them to share the biggest challenge they faced and also share one thing with the listeners of Computationally Yours that isn’t common knowledge about this testing. Dr. Sabah Kadri takes our listeners through some basics of SARS-CoV-2 (COVID-19) testing and lays out these unique challenges from our guests. Thank you to our guests: Dr. Karen Kaul (Chair of Pathology and Lab Medicine Northshore Univ Health System), Dr. Eric Konnick (Assistant Professor, Associate Director - Genetics and Solid Tumor Laboratory, Director - Genetics Pre-analytical Services at the Department of Laboratory Medicine and Pathology University of Washington), Dr. Julie Woolworth Hirschhorn (Assistant Professor, Associate Director Molecular Pathology at Medical University of South Carolina) and an unnamed molecular pathologist at a large hospital in Texas. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Website: http://computationallyyours.netlify.app/ Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on Instagram here. Thumbnail image: Colin D from Unsplash.com
24:10
August 18, 2020
Episode 13: How do you launch a genetic test?
In this episode, hosts, Dr. Sabah Kadri and Arshi Arora dive deep into the launch of a genetic test - what does it mean? What are the types of genetic testing? What goes into designing a genetic test? What is involved in validating this test clinically? What are the accuracy metrics? An easy listen covering a very complex topic. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Website: http://computationallyyours.netlify.app/ Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here.
23:30
August 11, 2020
Episode 12: Clinical Practitioners of Precision Medicine
In this episode, hosts, Dr. Sabah Kadri and Arshi Arora ask leading experts in Molecular Pathology across clinical laboratories across the United States, their personal experience with Precision Medicine, its effect on their clinical practice as well as their views of the future of personalized medicine. Ours guests for this episode are: Dr. Rashmi Kanagal-Shamanna, Hematopathologist, Molecular Genetic Pathologist, Associate Professor at MD Anderson Cancer Center Dr. Mark Ewalt, Hematopathologist at Memorial Sloan Kettering Dr. Alanna Church, Associate Director, LaMPP at Boston Children's Hospital Assistant Professor of Pathology, Harvard Medical School Dr. Joshua Coleman , Assistant Professor of Pathology at the University of Utah and Medical Director at ARUP Laboratories Dr. Kailee Yap, Director of Molecular Diagnostics, Assistant Professor of Pathology from Lurie Children’s hospital Dr. Somak Roy, Assistant Professor and Molecular Pathologist, The University of Pittsburgh Medical Center Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here. Thumbnail image: Pixabay Public Domain Picture
23:18
July 28, 2020
Episode 11: Precision Medicine 101
Did you know there was a time when no one knew about blood groups so no one knew to check the blood group of a donor before transfusion? There was also a time when a patient's treatment could not be tailored to their DNA changes. But none of that happens today. Do you know why? And do you know how? Listen to Dr. Sabah Kadri break down precision medicine and its revolutionary effects on patient care in this extremely engaging episode. We take an anecdote-filled roller coaster from the 1800s to 2020. Enjoy the ride! Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Follow us on Instagram here. Original Intro/Outro music: Riatsu (Shadaab Kadri) References: What is personalized medicine: sharpening a vague term based on a systematic literature review: https://pubmed.ncbi.nlm.nih.gov/24359531/ Jones DS. How personalized medicine became genetic, and racial: Werner Kalow and the formations of pharmacogenetics. J Hist Med Allied Sci. 2013;68(1):1-48. doi:10.1093/jhmas/jrr046 https://www.acc.org/latest-in-cardiology/articles/2018/10/14/12/42/harold-on-history-the-evolution-of-personalized-medicine https://www.cancer.gov/about-cancer/treatment/types/targeted-therapies/targeted-therapies-fact-sheet https://www.cancer.gov/about-cancer/treatment/clinical-trials/search Hugo A. Barrera-Saldaña, Origin of personalized medicine in pioneering, passionate, genomic research,Genomics, Volume 112, Issue 1, 2020
17:09
July 21, 2020
Episode 10: Know Your Hosts
Our hosts, Dr. Sabah Kadri and Arshi Arora are women in science celebrating a friendship that spans over a decade. In this episode, we get up-close and personal to get to know our hosts, their journeys in science and the hardships along the way. They discuss what excites them about science (Spoiler alert: it's everything), an embarrassing revelation and advice for young scientists starting out in the field. Join us in getting to know the people who bring you Computationally Yours. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here.
18:24
July 14, 2020
Episode 9: The inspiring story of Barbara McClintock
In our first "Profiles in Scientific Genius" series, we discuss the inspiring story of Dr. Barbara McClintock (1902-1992),  the first woman to have received a solo Nobel Prize in Physiology or Medicine. Achieving success against all odds, her story will make you believe. Dr. Sabah Kadri and Arshi Arora peek into her childhood, her support system, the odds she faced when she wanted to research in genetics at a time that women were not accepted into that department, and her eventual triumph in the field.  Link to National Academy of Science: http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/mcclintock-barbara.pdf Research Review: https://www.pnas.org/content/109/50/20198 Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here. Photo from Cold Spring Harbor.
14:53
July 7, 2020
Episode 8: What makes us different and the same: Genetic Variation
Our DNA makes us unique. It also makes us similar to each other - sometimes more and sometimes less. How? Dr. Sabah Kadri and Arshi Arora explore similarities and differences in our DNA. And in the process, they discuss milestone genomics projects in human beings such as dbSNP, the HapMap project and Genome Wide Association Studies. They look at studies all the way from one that looks at genetic factors involved in Covid-19 to one that investigates the genetics of curly hair. This one is a fun ride. Link to papers discussed: GWAS Covid study: https://www.nejm.org/doi/full/10.1056/NEJMoa2020283 Biology and genetics of curly hair: https://onlinelibrary.wiley.com/doi/full/10.1111/exd.13347 GWAS and HapMap https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717504/ Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here. Thumbnail from Pixabay. Thanks to @eliaas.sch
21:01
June 30, 2020
Episode 7: (Not so) Junk DNA
Next stop on the Genomics train is Junk DNA - the non-coding part of the genome. Dr. Sabah Kadri does a deep dive into the parts of the genome that we are still trying to understand. She highlights the major milestones in the field, its achievements and challenges, peppered with the usual origin stories and fun anecdotes from scientific history. Links to papers in the episode:  Susumo Ohno: http://www.junkdna.com/ohno.html Studies on functions of non-coding DNA: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447085/, https://www.nature.com/articles/s41588-019-0420-0 Functional definition and its controversy: https://www.journals.uchicago.edu/doi/full/10.1086/676588 A fun read: https://science.sciencemag.org/content/263/5147/608 Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on Instagram here. Follow us on YouTube here.
19:33
June 23, 2020
Episode 6: Microbial Genomics
Ever wonder what it is like to study the genomics of microbes likes bacteria and viruses? Dr. Sabah Kadri talks with Dr. Egon Ozer about the field of microbial genomics, the relatively fast evolution of microbes and the study from Dr. Ozer's group studying the genomic sequences of SARS-CoV-2, the virus in the COVID-19 pandemic. Tune in as we learn about this field, its challenges and methodologies. Link to paper discussed: https://www.medrxiv.org/content/10.1101/2020.05.19.20107144v1 Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here.
24:41
June 16, 2020
Episode 5: Human Genome Project
Dr. Sabah Kadri and Arshi Arora discuss the landmark project that changed genomics and bioinformatics forever: The Human Genome project. They discuss the what, why and how as well as the interesting stories that mark the journey of the human genome. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram https://www.instagram.com/computationallyours/ Website: http://computationallyyours.netlify.app/
21:16
June 9, 2020
May 26th: Announcement
Instead of a full episode, we have a quick announcement about what is to come in the month of June! This is so exciting. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram https://www.instagram.com/computationallyours/ Website: http://computationallyyours.netlify.app/
01:54
May 26, 2020
Episode 4: Clinical Trials for Infectious diseases
Infectious disease expert, Dr. Andrew Trotter discusses clinical trials in infectious diseases with Dr. Sabah Kadri and Arshi Arora in this episode of Computationally Yours. This is Part 2 in a 2-part series on clinical trials. We dive into what makes clinical trials in infectious diseases or conducting trials for vaccines different, and the importance of participation of patients in these trials. This episode makes complex concepts simple and approachable #accesibleScience Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram https://www.instagram.com/computationallyours/ Website: http://computationallyyours.netlify.app/
24:58
May 19, 2020
Episode 3: Clinical Trials 101
Dr. Sabah Kadri and Arshi Arora discuss the basics of clinical trials and give the listeners a fun 101 course on how trials are designed and some fundamental concepts of the process. You do not need to be an expert in Science to learn about Clinical Trials with us #accessibleScience Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: @compbiopodcast ; Dr. Sabah Kadri: @sabahkadri ; Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here. Follow us on Instagram here.
23:25
May 12, 2020
Episode2: Contact Tracing
In our second episode, Dr. Nicholas Soulakis breaks down Contact Tracing for our listeners and discusses the role of data and computational modeling in the contact tracing program. Dr. Soulakis is a career epidemiologist currently supporting the contact tracing program for the Illinois Department of Public Health. #accessibleScience #contactTracing Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com Follow us on Twitter: Computationally Yours Official Account: @compbiopodcast Dr. Sabah Kadri: @sabahkadri Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here.
26:29
May 12, 2020
Episode1: Hello World
The very first episode of our podcast. Get to know us a little, why we started this podcast and find out what happens when we assign ourselves the task to learn about the origins of Computational Biology. Contact us with questions, feedback and requests to collaborate on future episodes at computationallyyours@gmail.com. Follow us on Twitter: Computationally Yours Official Account: @compbiopodcast Dr. Sabah Kadri: @sabahkadri Arshi Arora: @arorarshi Intro/Outro music: Riatsu (Shadaab Kadri) Follow us on YouTube here.
15:00
April 28, 2020